Alitretinoin

retinoid X receptor alpha ; Homo sapiens







194 Article(s)
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1 35312737 The kinesin KIF4 mediates HBV/HDV entry through the regulation of surface NTCP localization and can be targeted by RXR agonists in vitro. 2022 Mar 1
2 31874245 miR-191 promotes radiation resistance of prostate cancer through interaction with RXRA. 2020 Mar 31 1
3 31928714 VHL enhances 9-cis-retinoic acid treatment by down-regulating retinoid X receptor α in renal cell carcinomas. 2020 Mar 5 2
4 32290525 Of Retinoids and Organotins: The Evolution of the Retinoid X Receptor in Metazoa. 2020 Apr 11 2
5 30198914 Effects of 9-cis-retinoic acid on the proliferation and apoptosis of cutaneous T-cell lymphoma cells. 2019 Jan 1
6 31298602 Therapeutic modulation of retinoid X receptors - SAR and therapeutic potential of RXR ligands and recent patents. 2019 Aug 2
7 29621670 Characterization and comparison of transcriptional activities of the retinoid X receptors by various organotin compounds in three prosobranch gastropods; Thais clavigera, Nucella lapillus and Babylonia japonica. 2018 Jun 5
8 29934308 Structural insights into the heterodimeric complex of the nuclear receptors FXR and RXR. 2018 Aug 10 1
9 28589840 Characterization of a Sea Urchin IQ Motif Containing Protein D as a Coactivator of Nuclear Receptors. 2017 Jun 2
10 28741179 Activation of liver X receptor inhibits OCT2-mediated organic cation transport in renal proximal tubular cells. 2017 Nov 3
11 28846104 Berberine binds RXRα to suppress β-catenin signaling in colon cancer cells. 2017 Dec 14 4
12 28975052 Trichoplax adhaerens reveals a network of nuclear receptors sensitive to 9-cis-retinoic acid at the base of metazoan evolution. 2017 4
13 27725436 Ligand Activity of Group 15 Compounds Possessing Triphenyl Substituent for the RXR and PPARγ Nuclear Receptors. 2016 2
14 25541638 RXR agonist modulates TR: corepressor dissociation upon 9-cis retinoic acid treatment. 2015 Feb 2
15 25728751 Retinoid X receptor α overexpression alleviates mitochondrial dysfunction-induced insulin resistance through transcriptional regulation of insulin receptor substrate 1. 2015 Apr 1
16 25736222 Inhibition of lipopolysaccharide-induced gene expression by liver X receptor ligands in macrophages involves interference with early growth response factor 1. 2015 May 1
17 25752819 Protein Kinase C Is Involved in the Induction of ATP-Binding Cassette Transporter A1 Expression by Liver X Receptor/Retinoid X Receptor Agonist in Human Macrophages. 2015 Sep 1
18 25953328 Protein Kinase C Is Involved in the Induction of ATP-Binding Cassette Transporter A1 Expression by Liver X Receptor/Retinoid X Receptor Agonist in Human Macrophages. 2015 May 7 1
19 25985376 Transactivation of the human retinoid X receptor by organotins: use of site-directed mutagenesis to identify critical amino acid residues for organotin-induced transactivation. 2015 Jul 4
20 26156677 NSC-640358 acts as RXRα ligand to promote TNFα-mediated apoptosis of cancer cell. 2015 Sep 1
21 26519880 Thyroid hormones upregulate apolipoprotein E gene expression in astrocytes. 2015 Dec 4-11 2
22 26544573 A ligand-entry surface of the nuclear receptor superfamily consists of the helix H3 of the ligand-binding domain. 2015 Nov 1
23 24388199 A recombinant PPRE-driven luciferase bioassay for identification of potential PPAR agonists. 2014 1
24 24498423 Human FXR regulates SHP expression through direct binding to an LRH-1 binding site, independent of an IR-1 and LRH-1. 2014 2
25 24962882 RXRs: collegial partners. 2014 2
26 25230277 NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma. 2014 Dec 15 2
27 25324544 β-Apo-13-carotenone regulates retinoid X receptor transcriptional activity through tetramerization of the receptor. 2014 Nov 28 4
28 23690070 Inflammatory mediators increase SUMOylation of retinoid X receptor α in a c-Jun N-terminal kinase-dependent manner in human hepatocellular carcinoma cells. 2013 Aug 6
29 24391011 RXR agonists inhibit high glucose-induced upregulation of inflammation by suppressing activation of the NADPH oxidase-nuclear factor-κB pathway in human endothelial cells. 2013 Dec 13 2
30 21983272 Analysis, occurrence, and function of 9-cis-retinoic acid. 2012 Jan 4
31 22573555 Regulation of the human endogenous retroviral Syncytin-1 and cell-cell fusion by the nuclear hormone receptors PPARγ/RXRα in placentogenesis. 2012 Jul 2
32 22949521 9-Cis-retinoic acid induces growth inhibition in retinoid-sensitive breast cancer and sea urchin embryonic cells via retinoid X receptor α and replication factor C3. 2012 Nov 3
33 23053561 The formation, occurrence, and function of β-apocarotenoids: β-carotene metabolites that may modulate nuclear receptor signaling. 2012 Nov 1
34 21382444 Binding affinities of CRBPI and CRBPII for 9-cis-retinoids. 2011 May 2
35 21489804 Replacement of the hydrophobic part of 9-cis-retinoic acid with cyclic terpenoid moiety results in RXR-selective agonistic activity. 2011 May 1 2
36 21654191 Bid as a potential target of apoptotic effects exerted by low doses of PPARγ and RXR ligands in breast cancer cells. 2011 Jul 15 1
37 21673049 Retinoid X receptor α and retinoids are key regulators in apoptosis of trophoblasts of patients with recurrent miscarriages. 2011 Oct 1
38 21945431 Delayed translocation of NGFI-B/RXR in glutamate stimulated neurons allows late protection by 9-cis retinoic acid. 2011 Oct 14 3
39 19653098 Environmental-endocrine control of reproductive maturation in gastropods: implications for the mechanism of tributyltin-induced imposex in prosobranchs. 2010 Jan 1
40 19784811 Retinoid X receptor agonists inhibit phorbol-12-myristate-13-acetate (PMA)-induced differentiation of monocytic THP-1 cells into macrophages. 2010 Feb 1
41 20176747 Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway. 2010 May 1
42 20398753 Theoretical study of molecular mechanism of binding TRAP220 coactivator to Retinoid X Receptor alpha, activated by 9-cis retinoic acid. 2010 Jul 3
43 20861222 Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells. 2010 Nov 1
44 21185985 [Retinoids: mechanisms of action]. 2010 Nov 2
45 19378296 Derivation of a retinoid X receptor scaffold from peroxisome proliferator-activated receptor gamma ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene. 2009 Jul 2
46 19644018 Combined low doses of PPARgamma and RXR ligands trigger an intrinsic apoptotic pathway in human breast cancer cells. 2009 Sep 1
47 19678713 Alitretinoin: in severe chronic hand eczema. 2009 Aug 20 2
48 19915048 Peroxisome proliferator-activated receptor gamma ligands enhance human B cell antibody production and differentiation. 2009 Dec 1 1
49 19920921 Alitretinoin--its use in intractable hand eczema and other potential indications. 2009 Sep 21 2
50 18082883 Retinoid X receptor alpha is highly phosphorylated in retinoic acid-resistant HL-60R cells and the combination of 9-cis retinoic acid plus MEK inhibitor induces apoptosis in the cells. 2008 Jun 3