nafamostat

transmembrane serine protease 2 ; Homo sapiens







20 Article(s)
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Pub. Year
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1 33868970 Virtual screening by targeting proteolytic sites of furin and TMPRSS2 to propose potential compounds obstructing the entry of SARS-CoV-2 virus into human host cells. 2022 Jan 1
2 35063125 The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2. 2022 Feb 8 1
3 35072549 The discovery and development of transmembrane serine protease 2 (TMPRSS2) inhibitors as candidate drugs for the treatment of COVID-19. 2022 Mar 1
4 35215982 In Silico Analysis and Synthesis of Nafamostat Derivatives and Evaluation of Their Anti-SARS-CoV-2 Activity. 2022 Feb 14 5
5 35294338 Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry. 2022 Mar 23 1
6 33505639 Spontaneous binding of potential COVID-19 drugs (Camostat and Nafamostat) to human serine protease TMPRSS2. 2021 1
7 33821268 Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry. 2021 Jul 30 1
8 33996911 Computational Identification of a Putative Allosteric Binding Pocket in TMPRSS2. 2021 2
9 34075338 Structural insights and inhibition mechanism of TMPRSS2 by experimentally known inhibitors Camostat mesylate, Nafamostat and Bromhexine hydrochloride to control SARS-coronavirus-2: A molecular modeling approach. 2021 3
10 34100014 Synergistic block of SARS-CoV-2 infection by combined drug inhibition of the host entry factors PIKfyve kinase and TMPRSS2 protease. 2021 Aug 12 2
11 34209110 Identification of 13 Guanidinobenzoyl- or Aminidinobenzoyl-Containing Drugs to Potentially Inhibit TMPRSS2 for COVID-19 Treatment. 2021 Jun 30 1
12 34340553 The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19. 2021 Aug 31 1
13 34406858 Synergistic Block of SARS-CoV-2 Infection by Combined Drug Inhibition of the Host Entry Factors PIKfyve Kinase and TMPRSS2 Protease. 2021 Oct 13 2
14 34406864 TMPRSS2 Activates Hemagglutinin-Esterase Glycoprotein of Influenza C Virus. 2021 Oct 13 1
15 34575594 Co-Spray Dried Nafamostat Mesylate with Lecithin and Mannitol as Respirable Microparticles for Targeted Pulmonary Delivery: Pharmacokinetics and Lung Distribution in Rats. 2021 Sep 19 1
16 34590967 Identification of potent inhibitors against transmembrane serine protease 2 for developing therapeutics against SARS-CoV-2. 2021 Sep 30 1
17 34787160 Targeting mechanism for SARS-CoV-2 in silico: interaction and key groups of TMPRSS2 toward four potential drugs. 2021 Nov 25 3
18 32532094 The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner. 2020 Jun 10 3
19 32824674 Sex Hormones and Hormone Therapy during COVID-19 Pandemic: Implications for Patients with Cancer. 2020 Aug 18 1
20 33382023 Fisetin 8-C-glucoside as entry inhibitor in SARS CoV-2 infection: molecular modelling study. 2020 Dec 31 1