| 51 |
28156185 | Evidence of activation of the Nrf2 pathway in multiple sclerosis patients treated with delayed-release dimethyl fumarate in the Phase 3 DEFINE and CONFIRM studies. | 2017 Dec |
6 |
| 52 |
28181536 | The NRF2 transcriptional target, OSGIN1, contributes to monomethyl fumarate-mediated cytoprotection in human astrocytes. | 2017 Feb 9 |
6 |
| 53 |
28247911 | Opposing effects of Nrf2 and Nrf2-activating compounds on the NLRP3 inflammasome independent of Nrf2-mediated gene expression. | 2017 May |
2 |
| 54 |
28370349 | The nuclear factor (erythroid-derived 2)-like 2 (NRF2) antioxidant response promotes melanocyte viability and reduces toxicity of the vitiligo-inducing phenol monobenzone. | 2017 Jul |
1 |
| 55 |
28429615 | Regulation of vascular large-conductance calcium-activated potassium channels by Nrf2 signalling. | 2017 Jul |
1 |
| 56 |
28460056 | Dimethyl fumarate mediates Nrf2-dependent mitochondrial biogenesis in mice and humans. | 2017 Aug 1 |
2 |
| 57 |
28918452 | Pro-oxidant status and Nrf2 levels in psoriasis vulgaris skin tissues and dimethyl fumarate-treated HaCaT cells. | 2017 Sep |
1 |
| 58 |
29046485 | Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease. | 2017 Oct 19 |
1 |
| 59 |
29096692 | Donor variability may mask dimethyl fumarate's effects on nuclear factor E2-related factor 2 in human peripheral blood mononuclear cells. | 2017 Nov 2 |
6 |
| 60 |
29209333 | Inhibition of Acute Graft-versus-Host Disease with Retention of Graft-versus-Tumor Effects by Dimethyl Fumarate. | 2017 |
2 |
| 61 |
29363907 | Effect of dimethyl fumarate on heme oxygenase-1 expression in experimental allergic encephalomyelitis in rats. | 2017 |
1 |
| 62 |
27009601 | Repurposing the NRF2 Activator Dimethyl Fumarate as Therapy Against Synucleinopathy in Parkinson's Disease. | 2016 Jul 10 |
4 |
| 63 |
27192495 | The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update. | 2016 Sep |
2 |
| 64 |
27725119 | Dimethyl fumarate alters microglia phenotype and protects neurons against proinflammatory toxic microenvironments. | 2016 Oct 15 |
1 |
| 65 |
27725581 | Recent advances in elucidating KEAP1-NRF2 functions in hematopoietic/immune cells and leukemic cells. | 2016 |
1 |
| 66 |
27774309 | Microparticulate/Nanoparticulate Powders of a Novel Nrf2 Activator and an Aerosol Performance Enhancer for Pulmonary Delivery Targeting the Lung Nrf2/Keap-1 Pathway. | 2016 |
1 |
| 67 |
25303683 | Permanent culture of macrophages at physiological oxygen attenuates the antioxidant and immunomodulatory properties of dimethyl fumarate. | 2015 May |
2 |
| 68 |
25449120 | Dimethyl fumarate attenuates 6-OHDA-induced neurotoxicity in SH-SY5Y cells and in animal model of Parkinson's disease by enhancing Nrf2 activity. | 2015 Feb 12 |
5 |
| 69 |
25584071 | Dimethyl fumarate in the treatment of relapsing-remitting multiple sclerosis: an overview. | 2015 Jan |
2 |
| 70 |
25793262 | Dimethyl fumarate and monoethyl fumarate exhibit differential effects on KEAP1, NRF2 activation, and glutathione depletion in vitro. | 2015 |
3 |
| 71 |
25842911 | [Extending therapeutic possibilities in relapsing-remitting multiple sclerosis: dimethyl fumarate]. | 2015 Jan 30 |
1 |
| 72 |
26004161 | DMF, but not other fumarates, inhibits NF-κB activity in vitro in an Nrf2-independent manner. | 2015 Jun 15 |
2 |
| 73 |
26044512 | Potential drugs which activate nuclear factor E2-related factor 2 signaling to prevent diabetic cardiovascular complications: A focus on fumaric acid esters. | 2015 Aug 1 |
1 |
| 74 |
26188148 | Nrf2 activators modulate oxidative stress responses and bioenergetic profiles of human retinal epithelial cells cultured in normal or high glucose conditions. | 2015 Sep |
3 |
| 75 |
24131282 | BG-12 (dimethyl fumarate): a review of mechanism of action, efficacy, and safety. | 2014 Feb |
2 |
| 76 |
25009787 | Dimethylfumarate attenuates restenosis after acute vascular injury by cell-specific and Nrf2-dependent mechanisms. | 2014 |
7 |
| 77 |
25019514 | Induction of heme oxygenase I (HMOX1) by HPP-4382: a novel modulator of Bach1 activity. | 2014 |
1 |
| 78 |
23637829 | Dimethylfumarate suppresses adipogenic differentiation in 3T3-L1 preadipocytes through inhibition of STAT3 activity. | 2013 |
3 |
| 79 |
23709213 | BG-12 in multiple sclerosis. | 2013 Feb |
1 |
| 80 |
24076006 | Effects of fumaric acid esters on blood-brain barrier tight junction proteins. | 2013 Oct 25 |
2 |
| 81 |
22769044 | Effects of dimethyl fumarate on neuroprotection and immunomodulation. | 2012 Jul 7 |
1 |
| 82 |
23109883 | Mechanisms of oxidative damage in multiple sclerosis and neurodegenerative diseases: therapeutic modulation via fumaric acid esters. | 2012 |
4 |