Dimethyl Fumarate

NFE2 like bZIP transcription factor 2 ; Homo sapiens







82 Article(s)
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1 33784961 Drugs Used in the Treatment of Multiple Sclerosis During COVID-19 Pandemic: A Critical Viewpoint. 2022 1
2 34292106 A comparison study between dimethyl itaconate and dimethyl fumarate in electrophilicity, Nrf2 activation, and anti-inflammation in vitro. 2022 Jun 5
3 35123595 [Effect of Dimethyl Fumarate (DMF) on T-cell Acute Lymphoblastic Leukemia]. 2022 Feb 2
4 35141161 Dimethyl Fumarate Combined With Vemurafenib Enhances Anti-Melanoma Efficacy via Inhibiting the Hippo/YAP, NRF2-ARE, and AKT/mTOR/ERK Pathways in A375 Melanoma Cells. 2022 2
5 35247778 7-deacetyl-gedunin suppresses proliferation of Human rheumatoid arthritis synovial fibroblast through activation of Nrf2/ARE signaling. 2022 Jun 2
6 35306364 Characterization of the modification of Kelch-like ECH-associated protein 1 by different fumarates. 2022 May 21 2
7 35624879 Thyroid Disorders in Patients Treated with Dimethyl Fumarate for Multiple Sclerosis: A Retrospective Observational Study. 2022 May 21 2
8 32672401 Structural insights into the multiple binding modes of Dimethyl Fumarate (DMF) and its analogs to the Kelch domain of Keap1. 2021 Mar 4
9 33468560 Different Fumaric Acid Esters Elicit Distinct Pharmacologic Responses. 2021 Mar 2
10 33931960 Dimethyl fumarate prevents ferroptosis to attenuate acute kidney injury by acting on NRF2. 2021 Apr 1
11 34426902 Dimethyl fumarate prevents cytotoxicity and apoptosis mediated by oxidative stress in human adipose-derived mesenchymal stem cells. 2021 Sep 5
12 34754326 Dimethyl Fumarate Ameliorates Nucleus Pulposus Cell Dysfunction through Activating the Nrf2/HO-1 Pathway in Intervertebral Disc Degeneration. 2021 5
13 32247228 Dimethyl fumarate promotes B cell-mediated anti-inflammatory cytokine profile in B and T cells, and inhibits immune cell migration in patients with MS. 2020 Jun 15 3
14 32316115 Potential Benefits of Nrf2/Keap1 Targeting in Pancreatic Islet Cell Transplantation. 2020 Apr 16 2
15 32553625 Dimethyl fumarate prevents osteoclastogenesis by decreasing NFATc1 expression, inhibiting of erk and p38 MAPK phosphorylation, and suppressing of HMGB1 release. 2020 Sep 17 3
16 32581803 Eye-Light on Age-Related Macular Degeneration: Targeting Nrf2-Pathway as a Novel Therapeutic Strategy for Retinal Pigment Epithelium. 2020 1
17 32708926 Antioxidant and Anti-inflammatory Effect of Nrf2 Inducer Dimethyl Fumarate in Neurodegenerative Diseases. 2020 Jul 17 3
18 32756501 Exploring the Use of Dimethyl Fumarate as Microglia Modulator for Neurodegenerative Diseases Treatment. 2020 Aug 3 1
19 32784785 Current Landscape of NRF2 Biomarkers in Clinical Trials. 2020 Aug 7 1
20 32811823 Computational repositioning of dimethyl fumarate for treating alcoholic liver disease. 2020 Aug 18 4
21 32863237 Electrophilic Nrf2 activators and itaconate inhibit inflammation at low dose and promote IL-1β production and inflammatory apoptosis at high dose. 2020 Sep 2
22 33003644 NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on ROS Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation. 2020 Sep 29 1
23 33009401 SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate. 2020 Oct 2 3
24 33087130 Dimethyl fumarate reduces TNF and Plasmodium falciparum induced brain endothelium activation in vitro. 2020 Oct 21 2
25 33087717 Author Correction: SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate. 2020 Oct 21 1
26 33199994 Dimethyl fumarate protects nucleus pulposus cells from inflammation and oxidative stress and delays the intervertebral disc degeneration. 2020 Dec 1
27 33396641 Peripheral Blood NRF2 Expression as a Biomarker in Human Health and Disease. 2020 Dec 30 1
28 33396673 Dimethyl Fumarate Promotes the Survival of Retinal Ganglion Cells after Optic Nerve Injury, Possibly through the Nrf2/HO-1 Pathway. 2020 Dec 30 7
29 30051766 Dimethyl fumarate-associated transient bone marrow oedema syndrome. 2019 May 1
30 30256716 Modulating NRF2 in Disease: Timing Is Everything. 2019 Jan 6 1
31 30587509 Identification of Novel Protein Targets of Dimethyl Fumarate Modification in Neurons and Astrocytes Reveals Actions Independent of Nrf2 Stabilization. 2019 Mar 1
32 30820593 Insight into the mechanism of action of dimethyl fumarate in multiple sclerosis. 2019 Apr 2
33 31279969 Dimethyl fumarate alters intracellular Ca2+ handling in immune cells by redox-mediated pleiotropic effects. 2019 Sep 1
34 31300673 Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes. 2019 Jul 12 1
35 31650471 Treatment with Dimethyl Fumarate Enhances Cholinergic Transmission in Multiple Sclerosis. 2019 Nov 2
36 31658977 Nrf2 signaling links ER oxidative protein folding and calcium homeostasis in health and disease. 2019 Oct 1
37 31688588 Reducing Pancreatic Fibrosis Using Antioxidant Therapy Targeting Nrf2 Antioxidant Pathway: A Possible Treatment for Chronic Pancreatitis. 2019 Nov/Dec 1
38 28986302 Activation of Nrf2 might reduce oxidative stress in human granulosa cells. 2018 Jul 15 5
39 28990726 Multiple mechanisms of dimethyl fumarate in amyloid β-induced neurotoxicity in human neuronal cells. 2018 Feb 3
40 29121589 Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy. 2018 Apr 1
41 29447051 Targeting crosstalk between Nuclear factor (erythroid-derived 2)-like 2 and Nuclear factor kappa beta pathway by Nrf2 activator dimethyl fumarate in epileptogenesis. 2018 Oct 2
42 29507676 Dimethyl fumarate is highly cytotoxic in KRAS mutated cancer cells but spares non-tumorigenic cells. 2018 Feb 6 4
43 29529529 The putative interplay between DJ-1/NRF2 and Dimethyl Fumarate: A potentially important pharmacological target. 2018 Apr 3
44 29603404 A review of the mechanisms of action of dimethylfumarate in the treatment of psoriasis. 2018 Jun 1
45 29928650 The NRF2 pathway as potential biomarker for dimethyl fumarate treatment in multiple sclerosis. 2018 Jun 6
46 30283812 Mononuclear cell transcriptome changes associated with dimethyl fumarate in MS. 2018 Jul 1
47 28006954 The Neuroprotective Effect of Dimethyl Fumarate in an MPTP-Mouse Model of Parkinson's Disease: Involvement of Reactive Oxygen Species/Nuclear Factor-κB/Nuclear Transcription Factor Related to NF-E2. 2017 Sep 10 4
48 28069874 Dimethyl Fumarate Controls the NRF2/DJ-1 Axis in Cancer Cells: Therapeutic Applications. 2017 Mar 11
49 28108787 Dimethyl fumarate accelerates peripheral nerve regeneration via activation of the anti-inflammatory and cytoprotective Nrf2/HO-1 signaling pathway. 2017 Mar 1
50 28116039 Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase. 2017 2