Isothiocyanates

NFE2 like bZIP transcription factor 2 ; Homo sapiens







20 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 27911093 DNA Microarray Profiling Highlights Nrf2-Mediated Chemoprevention Targeted by Wasabi-Derived Isothiocyanates in HepG2 Cells. 2017 Jan 1
2 27989132 Dietary Phytochemicals and Cancer Chemoprevention: A Perspective on Oxidative Stress, Inflammation, and Epigenetics. 2016 Dec 19 1
3 25593219 Sulforaphane alleviates muscular dystrophy in mdx mice by activation of Nrf2. 2015 Jan 15 1
4 25672622 Nrf2, a master regulator of detoxification and also antioxidant, anti-inflammatory and other cytoprotective mechanisms, is raised by health promoting factors. 2015 Feb 25 1
5 25800511 The activation of the Nrf2/ARE pathway in HepG2 hepatoma cells by phytochemicals and subsequent modulation of phase II and antioxidant enzyme expression. 2015 Jun 1
6 26094214 Synergy between sulforaphane and selenium in protection against oxidative damage in colonic CCD841 cells. 2015 Jul 2
7 24533814 Updated research and applications of small molecule inhibitors of Keap1-Nrf2 protein-protein interaction: a review. 2014 1
8 23403058 Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. 2013 Apr 1
9 23781297 Mechanisms of Nrf2/Keap1-dependent phase II cytoprotective and detoxifying gene expression and potential cellular targets of chemopreventive isothiocyanates. 2013 2
10 23836589 Isothiocyanates protect against oxidized LDL-induced endothelial dysfunction by upregulating Nrf2-dependent antioxidation and suppressing NFκB activation. 2013 Nov 1
11 24454992 Health promoting effects of brassica-derived phytochemicals: from chemopreventive and anti-inflammatory activities to epigenetic regulation. 2013 1
12 22178957 Natural isothiocyanates: genotoxic potential versus chemoprevention. 2012 Apr-Jun 1
13 22377900 Target molecules of food phytochemicals: food science bound for the next dimension. 2012 May 1
14 22527941 Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2. 2012 Aug 1
15 21656528 Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates. 2011 Jul 2
16 20368435 Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia. 2010 Apr 20 2
17 18458837 The cancer chemopreventive actions of phytochemicals derived from glucosinolates. 2008 May 1
18 18048326 Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha. 2007 Dec 4 2
19 16506816 Effect of isothiocyanates on nuclear accumulation of NF-kappaB, Nrf2, and thioredoxin in caco-2 cells. 2006 Mar 8 1
20 16928811 Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2. 2006 Aug 1