lysophosphatidic acid

mitogen-activated protein kinase 3 ; Homo sapiens







44 Article(s)
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1 35526043 A novel role of lysophosphatidic acid (LPA) in human myeloma resistance to proteasome inhibitors. 2022 May 7 1
2 33794877 CREB-dependent LPA-induced signaling initiates a pro-fibrotic feedback loop between small airway basal cells and fibroblasts. 2021 Apr 1 2
3 33944929 Lysophosphatidic acid improves oocyte quality during IVM by activating the ERK1/2 pathway in cumulus cells and oocytes. 2021 May 29 4
4 31906413 Lysophosphatidic Acid Upregulates Recepteur D'origine Nantais Expression and Cell Invasion via Egr-1, AP-1, and NF-κB Signaling in Bladder Carcinoma Cells. 2020 Jan 1 2
5 32007501 Antidepressants induce profibrotic responses via the lysophosphatidic acid receptor LPA1. 2020 Apr 15 1
6 32392404 Calcium-Mediated Interactions Regulate the Subcellular Localization of Extracellular Signal-Regulated Kinases (ERKs). 2020 May 12 1
7 30403494 Lysophosphatidic acid represses autophagy in prostate carcinoma cells. 2019 Aug 1
8 28232483 Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17. 2017 Apr 14 1
9 28766061 Lysophosphatidic acid enhances human umbilical cord mesenchymal stem cell viability without differentiation via LPA receptor mediating manner. 2017 Oct 1
10 28943105 A549 cells as a model to study endogenous LPA1 receptor signaling and regulation. 2017 Nov 15 1
11 25564987 Lysophosphatidic acid improves porcine oocyte maturation and embryo development in vitro. 2015 Jan 4
12 25633408 Lysophosphatidic acid rescues bone mesenchymal stem cells from hydrogen peroxide-induced apoptosis. 2015 Mar 1
13 25888927 Antidepressants activate the lysophosphatidic acid receptor LPA(1) to induce insulin-like growth factor-I receptor transactivation, stimulation of ERK1/2 signaling and cell proliferation in CHO-K1 fibroblasts. 2015 Jun 15 1
14 26134517 Lysophosphatidic acid increases the proliferation and migration of adipose‑derived stem cells via the generation of reactive oxygen species. 2015 Oct 1
15 24792438 Lysophosphatidic acid-induced IL-8 secretion involves MSK1 and MSK2 mediated activation of CREB1 in human fibroblast-like synoviocytes. 2014 Jul 1 2
16 23747852 Regulation of angiogenesis by phospholipid lysophosphatidic acid. 2013 Jun 1 1
17 21925926 Secretion of IL-6 and IL-8 from lysophosphatidic acid-stimulated oral squamous cell carcinoma promotes osteoclastogenesis and bone resorption. 2012 Jan 1
18 22577133 Lysophosphatidic acid induces early growth response-1 (Egr-1) protein expression via protein kinase Cδ-regulated extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) activation in vascular smooth muscle cells. 2012 Jun 29 1
19 22820196 Inhibition of lipid phosphate phosphatase activity by VPC32183 suppresses the ability of diacylglycerol pyrophosphate to activate ERK(1/2) MAP kinases. 2012 Nov 1
20 22847216 Involvement of the cAMP response element binding protein, CREB, and cyclin D1 in LPA-induced proliferation of P19 embryonic carcinoma cells. 2012 Sep 2
21 19940066 Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells. 2010 Mar 1
22 20533299 LPA rescues ER stress-associated apoptosis in hypoxia and serum deprivation-stimulated mesenchymal stem cells. 2010 Nov 1 4
23 20576526 Non-transactivational, dual pathways for LPA-induced Erk1/2 activation in primary cultures of brown pre-adipocytes. 2010 Oct 1 10
24 20804754 Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription. 2010 Sep 24 2
25 18658095 ERK1/2 mediate wounding- and G-protein-coupled receptor ligands-induced EGFR activation via regulating ADAM17 and HB-EGF shedding. 2009 Jan 2
26 19656035 Lysophosphatidic Acid signals through specific lysophosphatidic Acid receptor subtypes to control key regenerative responses of human gingival and periodontal ligament fibroblasts. 2009 Aug 1
27 18762810 In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation. 2008 Nov 20 1
28 18958425 Regulation of lysophosphatidic acid-induced COX-2 expression by ERK1/2 activation in cultured feline esophageal epithelial cells. 2008 Oct 2
29 17531530 Lysophosphatidic acid induces prostate cancer PC3 cell migration via activation of LPA(1), p42 and p38alpha. 2007 Jul 3
30 17937769 Lysophosphatidic acid inhibits ghrelin secretion in the human gastric adenocarcinoma AGS cell line: role of mitogenic activated protein kinase signaling pathway. 2007 Nov 1
31 15657067 Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells. 2005 Apr 1
32 15728708 LPA2 receptor mediates mitogenic signals in human colon cancer cells. 2005 Jul 1
33 15107593 Regulation of mitogen-activated protein kinase cascades by low density lipoprotein and lysophosphatidic acid. 2004 1
34 15364923 Optimal lysophosphatidic acid-induced DNA synthesis and cell migration but not survival require intact autophosphorylation sites of the epidermal growth factor receptor. 2004 Nov 12 5
35 15581951 Upregulation of FasL by LPA on ovarian cancer cell surface leads to apoptosis of activated lymphocytes. 2004 Dec 1
36 12588763 Lysophosphatidic acid induction of tissue factor expression in aortic smooth muscle cells. 2003 Feb 1 3
37 12730329 Lysophosphatidic acid signals through mitogen-activated protein kinase-extracellular signal regulated kinase in ovarian theca cells expressing the LPA1/edg2-receptor: involvement of a nonclassical pathway? 2003 Aug 6
38 12812976 Protein kinase-A activity in PRKAR1A-mutant cells, and regulation of mitogen-activated protein kinases ERK1/2. 2003 Jul 1 4
39 11850124 Proline-rich tyrosine kinase 2 regulates proliferation and differentiation of prostate cells. 2002 Jan 15 3
40 12139919 Oligodendroglial expression of Edg-2 receptor: developmental analysis and pharmacological responses to lysophosphatidic acid. 2002 Jul 1
41 11522591 Assessment of agonism at G-protein coupled receptors by phosphatidic acid and lysophosphatidic acid in human embryonic kidney 293 cells. 2001 Sep 2
42 10706774 Role of lysophosphatidic acid and rho in glioma cell motility. 2000 Mar 1
43 11061948 Essential role for G proteins in prostate cancer cell growth and signaling. 2000 Dec 4
44 11062066 Lysophosphatidic acid prevents apoptosis in fibroblasts via G(i)-protein-mediated activation of mitogen-activated protein kinase. 2000 Nov 15 3