Cadmium

mitogen-activated protein kinase 3 ; Homo sapiens







51 Article(s)
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1 35524288 Melatonin modulates Nrf2 activity to protect porcine pre-pubertal Sertoli cells from the abnormal H2 O2 generation and reductive stress effects of cadmium. 2022 May 6 6
2 34580807 Cadmium affects autophagy in the human intestinal cells Caco-2 through ROS-mediated ERK activation. 2021 Sep 28 7
3 31860779 Zinc interference with Cd-induced hormetic effect in differentiated Caco-2 cells: Evidence for inhibition downstream ERK activation. 2020 Mar 5
4 32512071 Activation of the Erk/MAPK signaling pathway is a driver for cadmium induced prostate cancer. 2020 Aug 15 1
5 33075233 Cadmium induces CCL2 production in glioblastoma cells via activation of MAPK, PI3K, and PKC pathways. 2020 Dec 1
6 30682495 Evidences for involvement of estrogen receptor induced ERK1/2 activation in ovarian cancer cell proliferation by Cadmium Chloride. 2019 Apr 2
7 31190890 Downregulation of NSD3 (WHSC1L1) inhibits cell proliferation and migration via ERK1/2 deactivation and decreasing CAPG expression in colorectal cancer cells. 2019 1
8 31252067 Cadmium exposure induces interleukin-6 production via ROS-dependent activation of the ERK1/2 but independent of JNK signaling pathway in human placental JEG-3 trophoblast cells. 2019 Oct 4
9 31562949 Carvacrol inhibits cadmium toxicity through combating against caspase dependent/independent apoptosis in PC12 cells. 2019 Dec 4
10 28288823 Cadmium-induced IL-6 and IL-8 expression and release from astrocytes are mediated by MAPK and NF-κB pathways. 2017 May 1
11 30023612 Impact of Environmental Pollutant Cadmium on the Establishment of a Cancer Stem Cell Population in Breast and Hepatic Cancer. 2017 Feb 28 1
12 26716417 Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. 2016 Feb 2 5
13 26782637 Cadmium induces mucin 8 expression via Toll-like receptor 4-mediated extracellular signal related kinase 1/2 and p38 mitogen-activated protein kinase in human airway epithelial cells. 2016 Jun 12
14 27108949 From pure compounds to complex exposure: Effects of dietary cadmium and lignans on estrogen, epidermal growth factor receptor, and mitogen activated protein kinase signaling in vivo. 2016 Jun 24 2
15 25343777 Cadmium and proliferation in human uterine leiomyoma cells: evidence of a role for EGFR/MAPK pathways but not classical estrogen receptor pathways. 2015 Apr 1
16 25744307 Cadmium at nanomolar concentrations activates Raf-MEK-ERK1/2 MAPKs signaling via EGFR in human cancer cell lines. 2015 Apr 25 3
17 25998312 Cadmium Induced Apoptosis in MG63 Cells by Increasing ROS, Activation of p38 MAPK and Inhibition of ERK 1/2 Pathways. 2015 3
18 26006730 Requirement of ERα and basal activities of EGFR and Src kinase in Cd-induced activation of MAPK/ERK pathway in human breast cancer MCF-7 cells. 2015 Aug 15 4
19 26046303 Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium. 2015 Aug 28 10
20 26146868 Resveratrol prevents cadmium activation of Erk1/2 and JNK pathways from neuronal cell death via protein phosphatases 2A and 5. 2015 Nov 3
21 26248512 Calcium Signaling Involvement in Cadmium-Induced Astrocyte Cytotoxicity and Cell Death Through Activation of MAPK and PI3K/Akt Signaling Pathways. 2015 Sep 6
22 26514923 Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells. 2015 Dec 2 4
23 24973647 Redox activation of DUSP4 by N-acetylcysteine protects endothelial cells from Cd²⁺-induced apoptosis. 2014 Sep 1
24 25069788 Cadmium induces urokinase-type plasminogen activator receptor expression and the cell invasiveness of human gastric cancer cells via the ERK-1/2, NF-κB, and AP-1 signaling pathways. 2014 Oct 2
25 23405080 Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation. 2013 1
26 23966319 The ERK1/2 signaling pathway regulates 11beta-hydroxysteroid dehydrogenase type 2 expression in human trophoblast cells through a transcriptional mechanism. 2013 Oct 2
27 21697648 Cadmium-induced apoptosis and necrosis in human osteoblasts: role of caspases and mitogen-activated protein kinases pathways. 2012 Feb 1
28 22011313 Metalloestrogenic effects of quantum dots. 2012 Jan 1
29 22094458 An NF-κB-independent and Erk1/2-dependent mechanism controls CXCL8/IL-8 responses of airway epithelial cells to cadmium. 2012 Feb 4
30 22142850 Curcumin regulates airway epithelial cell cytokine responses to the pollutant cadmium. 2012 Jan 6 1
31 22659318 Cadmium-induced apoptosis in the BJAB human B cell line: involvement of PKC/ERK1/2/JNK signaling pathways in HO-1 expression. 2012 Oct 28 1
32 21544200 Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network. 2011 Apr 22 7
33 21933187 CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death. 2011 Dec 6
34 20153348 The membrane estrogen receptor GPR30 mediates cadmium-induced proliferation of breast cancer cells. 2010 May 15 3
35 20232314 Cadmium-induced hormetic effect in differentiated Caco-2 cells: ERK and p38 activation without cell proliferation stimulation. 2010 Jul 2
36 20868229 Cadmium ions promote monocytic differentiation of human leukemia HL-60 cells treated with 1α,25-dihydroxyvitamin D3. 2010 Nov 4
37 19028507 Inhibition of benzopyrene-diol-epoxide (BPDE)-induced bax and caspase-9 by cadmium: role of mitogen activated protein kinase. 2009 Feb 10 1
38 19041697 Effects of cadmium on estrogen receptor mediated signaling and estrogen induced DNA synthesis in T47D human breast cancer cells. 2009 Jan 30 3
39 19429262 NADPH oxidase and ERK1/2 are involved in cadmium induced-STAT3 activation in HepG2 cells. 2009 Jun 22 2
40 19524565 Cadmium-induced apoptotic death of human retinal pigment epithelial cells is mediated by MAPK pathway. 2009 Oct 3
41 19573589 Biphasic effect of cadmium on cell proliferation in human embryo lung fibroblast cells and its molecular mechanism. 2009 Sep 6
42 18021293 MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis. 2008 Apr 3
43 18275979 Rapid activation of ERK1/2 and AKT in human breast cancer cells by cadmium. 2008 May 1 7
44 18571719 Effects of cadmium on MAPK signalling pathways and HSP70 expression in a human trophoblast cell line. 2008 Aug 3
45 18703135 Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5. 2008 Oct 1 7
46 17125913 Cadmium induces mitogenic signaling in breast cancer cell by an ERalpha-dependent mechanism. 2007 Jan 29 3
47 17485079 Induction of functional MT1 and MT2 isoforms by calcium in anaplastic thyroid carcinoma cells. 2007 May 29 1
48 17637928 Acquisition of apoptotic resistance in cadmium-transformed human prostate epithelial cells: Bcl-2 overexpression blocks the activation of JNK signal transduction pathway. 2007 Jul 1
49 12508112 Heat shock and Cd2+ exposure regulate PML and Daxx release from ND10 by independent mechanisms that modify the induction of heat-shock proteins 70 and 25 differently. 2003 Feb 1 1
50 11709198 Potentiation of cadmium-induced cytotoxicity by sulfur amino acid deprivation through activation of extracellular signal-regulated kinase1/2 (ERK1/2) in conjunction with p38 kinase or c-jun N-terminal kinase (JNK). Complete inhibition of the potentiated toxicity by U0126 an ERK1/2 and p38 kinase inhibitor. 2001 Nov 15 1