2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

mitogen-activated protein kinase 3 ; Homo sapiens







941 Article(s)
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51 32860670 Sulforaphane-cysteine downregulates CDK4 /CDK6 and inhibits tubulin polymerization contributing to cell cycle arrest and apoptosis in human glioblastoma cells. 2020 Aug 29 1
52 33000206 Steroid receptor RNA activator inhibits the migration, invasion and stemness characteristics of renal cell carcinoma cells. 2020 Nov 1
53 33376407 Apolipoprotein E2 Promotes the Migration and Invasion of Pancreatic Cancer Cells via Activation of the ERK1/2 Signaling Pathway. 2020 1
54 30218208 Aloin promotes osteogenesis of bone-marrow-derived mesenchymal stem cells via the ERK1/2-dependent Runx2 signaling pathway. 2019 Jan 1
55 30246289 Tannic acid protects against experimental acute lung injury through downregulation of TLR4 and MAPK. 2019 May 2
56 30468278 Bufalin induces protective autophagy by Cbl-b regulating mTOR and ERK signaling pathways in gastric cancer cells. 2019 Jan 1
57 30499162 Kaempferol suppresses cell migration through the activation of the ERK signaling pathways in ARPE-19 cells. 2019 Mar 1
58 30509084 The AT1/Raf/ERK1/2 signaling pathway is involved in Angiotensin II-enhanced proliferation of hepatic carcinoma cells. 2019 Jan 15 1
59 30773423 Synthesis, antiproliferative and apoptosis induction potential activities of novel bis(indolyl)hydrazide-hydrazone derivatives. 2019 Mar 15 1
60 30787989 Downregulation of angiopoietin-like protein 2 inhibits cementoblast differentiation partially by activating the ERK1/2 signaling pathway. 2019 1
61 30839135 TNF-α mediated MEK-ERK signaling in invasion with putative network involving NF-κB and STAT-6: a new perspective in glioma. 2019 Nov 1
62 30879923 Cyclosporine A sensitizes lung cancer cells to crizotinib through inhibition of the Ca2+/calcineurin/Erk pathway. 2019 Apr 2
63 30987295 Mel1c Mediated Monochromatic Light-Stimulated IGF-I Synthesis through the Intracellular Gαq/PKC/ERK Signaling Pathway. 2019 Apr 4 1
64 31005035 The anti-angiogenic effect of tryptanthrin is mediated by the inhibition of apelin promoter activity and shortened mRNA half-life in human vascular endothelial cells. 2019 May 2
65 31190890 Downregulation of NSD3 (WHSC1L1) inhibits cell proliferation and migration via ERK1/2 deactivation and decreasing CAPG expression in colorectal cancer cells. 2019 1
66 31269957 Cathepsin L-induced galectin-1 may act as a proangiogenic factor in the metastasis of high-grade serous carcinoma. 2019 Jul 3 1
67 31389582 Silenced miR-21 inhibits renal interstitial fibrosis via targeting ERK1/2 signaling pathway in mice. 2019 Aug 1
68 31408162 Interleukin-1β inhibits estrogen receptor-α, progesterone receptors A and B and biomarkers of human endometrial stromal cell differentiation: implications for endometriosis. 2019 Oct 28 2
69 31485607 miR-217 inhibits the migration and invasion of HeLa cells through modulating MAPK1. 2019 Nov 1
70 31488097 Response of neuroblastoma cells to RF currents as a function of the signal frequency. 2019 Sep 5 1
71 31574951 Biological Effects of Shikonin in Human Gingival Fibroblasts via ERK 1/2 Signaling Pathway. 2019 Sep 30 1
72 31605603 IQ Motif Containing GTPase-Activating Protein 3 (IQGAP3) Inhibits Kaempferol-Induced Apoptosis in Breast Cancer Cells by Extracellular Signal-Regulated Kinases 1/2 (ERK1/2) Signaling Activation. 2019 Oct 12 1
73 31622878 Blockage of ROS-ERK-DLP1 signaling and mitochondrial fission alleviates Cr(VI)-induced mitochondrial dysfunction in L02 hepatocytes. 2019 Dec 30 2
74 31775870 Fibroblast growth factor-2 stimulates proliferation of human adipose-derived stem cells via Src activation. 2019 Nov 27 1
75 31786845 Effect of PD98059 on chemotherapy in patients with colorectal cancer through ERK1/2 pathway. 2019 Sep-Oct 5
76 31831776 ERK1/2 drives IL-1β-induced expression of TGF-β1 and BMP-2 in torn tendons. 2019 Dec 12 1
77 31950060 Tripartite Motif Containing 11 Interacts with DUSP6 to Promote the Growth of Human Osteosarcoma Cells through Regulating ERK1/2 Pathway. 2019 2
78 31971555 Antiapoptotic activity of Chlamydia trachomatis Pgp3 protein involves activation of the ERK1/2 pathway mediated by upregulation of DJ-1 protein. 2019 Dec 1 1
79 31975773 Role of MEK-ERK signaling mediated adhesion of glioma cells to extra-cellular matrix: Possible implication on migration and proliferation. 2019 Apr 2
80 28287251 Cisplatin induced apoptosis of ovarian cancer A2780s cells by activation of ERK/p53/PUMA signals. 2018 Jan 1
81 28328292 IL-6 is involved in malignancy and doxorubicin sensitivity of renal carcinoma cells. 2018 Jan 2 1
82 28688217 Yes-associated protein 1 promotes the differentiation and mineralization of cementoblast. 2018 Mar 1
83 28771713 EPA blocks TNF-α-induced inhibition of sugar uptake in Caco-2 cells via GPR120 and AMPK. 2018 Mar 1
84 28871467 Epigallocatechin gallate protects against homocysteine-induced vascular smooth muscle cell proliferation. 2018 Feb 1
85 28885729 Leptin induces matrix metalloproteinase 7 expression to promote ovarian cancer cell invasion by activating ERK and JNK pathways. 2018 Feb 1
86 29215709 The potential role of aquaporin 1 on aristolochic acid I induced epithelial mesenchymal transition on HK-2 cells. 2018 Jun 4
87 29241073 Resveratrol inhibits proliferation, migration and invasion via Akt and ERK1/2 signaling pathways in renal cell carcinoma cells. 2018 Feb 2
88 29349514 NB-UVB irradiation downregulates keratin-17 expression in keratinocytes by inhibiting the ERK1/2 and STAT3 signaling pathways. 2018 Mar 1
89 29394342 PTH1R signalling regulates the mechanotransduction process of cementoblasts under cyclic tensile stress. 2018 Sep 28 2
90 29405768 Diepoxybutane-induced apoptosis is mediated through the ERK1/2 pathway. 2018 Oct 1
91 29410403 Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo. 2018 Feb 6 1
92 29461611 Leptin inhibits apoptosis of nucleus pulposus cells via promoting autophagy. 2018 Feb 1
93 29528486 High-power, red-light-emitting diode irradiation enhances proliferation, osteogenic differentiation, and mineralization of human periodontal ligament stem cells via ERK signaling pathway. 2018 Mar 1
94 29578002 Inhibition of microRNA-34a protects against propofol anesthesia-induced neurotoxicity and cognitive dysfunction via the MAPK/ERK signaling pathway. 2018 May 14 1
95 29580882 Astrocytes and neurons in locus coeruleus mediate restraint water immersion stress-induced gastric mucosal damage through the ERK1/2 signaling pathway. 2018 May 14 1
96 29615689 Involvement of RSK1 activation in malformin-enhanced cellular fibrinolytic activity. 2018 Apr 3 1
97 29678550 Low-level shear stress promotes migration of liver cancer stem cells via the FAK-ERK1/2 signalling pathway. 2018 Jul 28 2
98 29731895 Upregulation of seladin-1 and nestin expression in bone marrow mesenchymal stem cell transplantation via the ERK1/2 and PI3K/Akt signaling pathways in an Alzheimer's disease model. 2018 May 1
99 29731988 Cisplatin-induced ERK1/2 activity promotes G1 to S phase progression which leads to chemoresistance of ovarian cancer cells. 2018 Apr 13 4
100 29766336 Ischaemic Preconditioning Protects Cardiomyocytes from Anthracycline-Induced Toxicity via the PI3K Pathway. 2018 Jun 1