Wortmannin

mitogen-activated protein kinase 3 ; Homo sapiens







65 Article(s)
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1 33582643 Insight into the mechanism of tetrachlorobisphenol A (TCBPA)-induced proliferation of breast cancer cells by GPER-mediated signaling pathways. 2021 Apr 15 1
2 32733640 PI3K/Akt and ERK1/2 Signalling Are Involved in Quercetin-Mediated Neuroprotection against Copper-Induced Injury. 2020 1
3 30838710 Insulin promotes invasion and migration of KRASG12D mutant HPNE cells by upregulating MMP-2 gelatinolytic activity via ERK- and PI3K-dependent signalling. 2019 May 2
4 31005035 The anti-angiogenic effect of tryptanthrin is mediated by the inhibition of apelin promoter activity and shortened mRNA half-life in human vascular endothelial cells. 2019 May 2
5 28381122 Argon Exposure Induces Postconditioning in Myocardial Ischemia-Reperfusion. 2017 Nov 1
6 28395342 Stimulatory effects of fibroblast growth factor 2 on proliferation and migration of uterine luminal epithelial cells during early pregnancy. 2017 Jan 1 2
7 28694915 Heme Oxygenase-1, a Key Enzyme for the Cytoprotective Actions of Halophenols by Upregulating Nrf2 Expression via Activating Erk1/2 and PI3K/Akt in EA.hy926 Cells. 2017 1
8 27208795 Biased signaling initiated by agouti-related peptide through human melanocortin-3 and -4 receptors. 2016 Sep 1
9 27591897 The Vascular Endothelial Growth Factor-A phosphorylates Murine Double Minute-2 on its Serine 166 via the Extracellular Signal-Regulated Kinase 1/2 and p90 Ribosomal S6 Kinase in primary human endothelial cells. 2016 Sep 30 1
10 25817573 Neuropeptide Y receptor mediates activation of ERK1/2 via transactivation of the IGF receptor. 2015 Jul 1
11 24617901 IKVAV regulates ERK1/2 and Akt signalling pathways in BMMSC population growth and proliferation. 2014 Apr 1
12 25034934 FTY720 attenuates hypoxia-reoxygenation-induced apoptosis in cardiomyocytes. 2014 Oct 1
13 22809535 Ghrelin induces cardiac lineage differentiation of human embryonic stem cells through ERK1/2 pathway. 2013 Sep 10 2
14 22908970 The proliferative effects of ghrelin on human gastric cancer AGS cells. 2012 Sep 1
15 21056559 Macrophage-induced preadipocyte survival depends on signaling through Akt, ERK1/2, and reactive oxygen species. 2011 Feb 15 1
16 20416296 Involvement of androgen receptor in nitric oxide production induced by icariin in human umbilical vein endothelial cells. 2010 Jun 3 1
17 20506505 Overexpression of fucosyltransferase IV promotes A431 cell proliferation through activating MAPK and PI3K/Akt signaling pathways. 2010 Nov 1
18 18941890 Reactive oxygen species induce phosphorylation of serine 118 and 167 on estrogen receptor alpha. 2009 Nov 1
19 19344769 Tetanus toxin H(C) fragment reduces neuronal MPP+ toxicity. 2009 Jul 1
20 19428994 Melanocortin 5 receptor activates ERK1/2 through a PI3K-regulated signaling mechanism. 2009 May 6 1
21 19671683 Roles of MKK1/2-ERK1/2 and phosphoinositide 3-kinase-AKT signaling pathways in erlotinib-induced Rad51 suppression and cytotoxicity in human non-small cell lung cancer cells. 2009 Aug 1
22 17186496 Obestatin-mediated proliferation of human retinal pigment epithelial cells: regulatory mechanisms. 2007 Apr 1
23 17188372 Melanocortin-3 receptor activates MAP kinase via PI3 kinase. 2007 Mar 1 1
24 17275785 Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells. 2007 Mar 23 1
25 17350964 PI3K/Akt and ERK1/2 signalling pathways are involved in endometrial cell migration induced by 17beta-estradiol and growth factors. 2007 May 1
26 17539658 Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-beta1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase cascade signaling. 2007 Jun 27 1
27 17827719 Water extract of Korean red ginseng stimulates angiogenesis by activating the PI3K/Akt-dependent ERK1/2 and eNOS pathways in human umbilical vein endothelial cells. 2007 Sep 1
28 17975262 Rac2 GTPase activation by angiotensin II is modulated by Ca2+/calcineurin and mitogen-activated protein kinases in human neutrophils. 2007 Nov 1
29 16166591 The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory states. 2006 Jan 15 1
30 16239258 The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells. 2006 Mar 1
31 16406609 PI3K is required for insulin-stimulated but not EGF-stimulated ERK1/2 activation. 2006 May 1
32 16630729 Stromal cell derived factor-1 acutely promotes neural progenitor cell proliferation in vitro by a mechanism involving the ERK1/2 and PI-3K signal pathways. 2006 May 1
33 15468165 Vasoactive intestinal peptide induces neuroendocrine differentiation in the LNCaP prostate cancer cell line through PKA, ERK, and PI3K. 2005 Apr 1 1
34 16128807 Acute activation of Erk1/Erk2 and protein kinase B/akt proceed by independent pathways in multiple cell types. 2005 Sep 1
35 16207820 Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways. 2005 Dec 1
36 14751283 Neuroprotection by transforming growth factor-beta1 involves activation of nuclear factor-kappaB through phosphatidylinositol-3-OH kinase/Akt and mitogen-activated protein kinase-extracellular-signal regulated kinase1,2 signaling pathways. 2004 2
37 14985355 Stem cell factor/c-kit signaling promotes the survival, migration, and capillary tube formation of human umbilical vein endothelial cells. 2004 Apr 30 1
38 15069082 ERK1/2 mediates insulin stimulation of Na(+),K(+)-ATPase by phosphorylation of the alpha-subunit in human skeletal muscle cells. 2004 Jun 11 1
39 15235105 Both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signalling are required in epidermal growth factor-induced human trophoblast migration. 2004 Sep 1
40 15313431 C5a differentially stimulates the ERK1/2 and p38 MAPK phosphorylation through independent signaling pathways to induced chemotactic migration in RAW264.7 macrophages. 2004 Oct 1
41 12505872 Physiological concentration of atrial natriuretic peptide induces endothelial regeneration in vitro. 2003 Apr 1
42 12689930 Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor. 2003 Aug 15 3
43 14516795 Hydrogen peroxide mediates arsenite activation of p70(s6k) and extracellular signal-regulated kinase. 2003 Oct 15 2
44 14516797 The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38. 2003 Oct 15 1
45 11739687 E5 protein of human papillomavirus type 16 protects human foreskin keratinocytes from UV B-irradiation-induced apoptosis. 2002 Jan 4
46 11902114 Phosphatidylinositol 3-kinase is a central mediator of NMDA receptor signalling to MAP kinase (Erk1/2), Akt/PKB and CREB in striatal neurones. 2002 Jan 1
47 11994364 Mitogen-activated protein kinase cascade in human normal and tumoral parathyroid cells. 2002 May 1
48 12191495 Muscarine enhances soluble amyloid precursor protein secretion in human neuroblastoma SH-SY5Y by a pathway dependent on protein kinase C(alpha), src-tyrosine kinase and extracellular signal-regulated kinase but not phospholipase C. 2002 Jun 15 2
49 12411472 Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands. 2002 Nov 3
50 12414747 Lipoarabinomannan-induced cell signaling involves ceramide and mitogen-activated protein kinase. 2002 Nov 1