| 1 |
33864571 | Upregulated SOCC and IP3R calcium channels and subsequent elevated cytoplasmic calcium signaling promote nonalcoholic fatty liver disease by inhibiting autophagy. | 2021 Aug |
2 |
| 2 |
34274968 | MiR-592 activates the mTOR kinase, ERK1/ERK2 kinase signaling and imparts neuronal differentiation signature characteristic of Group 4 medulloblastoma. | 2021 Nov 30 |
1 |
| 3 |
31921404 | TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling. | 2020 |
1 |
| 4 |
32062191 | Rapamycin inhibits B-cell activating factor (BAFF)-stimulated cell proliferation and survival by suppressing Ca2+-CaMKII-dependent PTEN/Akt-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells. | 2020 May |
4 |
| 5 |
32104716 | Chloroquine and Rapamycin Augment Interleukin-37 Expression via the LC3, ERK, and AP-1 Axis in the Presence of Lipopolysaccharides. | 2020 |
1 |
| 6 |
32495040 | CREB activity is required for mTORC1 signaling-induced primordial follicle activation in mice. | 2020 Sep |
2 |
| 7 |
32848709 | Rapamycin, by Inhibiting mTORC1 Signaling, Prevents the Loss of Striatal Bidirectional Synaptic Plasticity in a Rat Model of L-DOPA-Induced Dyskinesia. | 2020 |
1 |
| 8 |
30958627 | IgA1 isolated from Henoch-Schönlein purpura children promotes proliferation of human mesangial cells in vitro. | 2019 Jul |
1 |
| 9 |
28734155 | Activation of mTOR is involved in anti-β2GPI/β2GPI-induced expression of tissue factor and IL-8 in monocytes. | 2017 Sep |
1 |
| 10 |
28963126 | EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. | 2017 Sep |
1 |
| 11 |
27616194 | Rapamycin regulates the proliferation of Huh7, a hepatocellular carcinoma cell line, by up-regulating p53 expression. | 2016 Oct 7 |
2 |
| 12 |
25069858 | Activation of autophagy by rapamycin does not protect oligodendrocytes against protein aggregate formation and cell death induced by proteasomal inhibition. | 2015 Jan |
1 |
| 13 |
26046303 | Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium. | 2015 Aug 28 |
1 |
| 14 |
26118661 | Rapamycin inhibits BAFF-stimulated cell proliferation and survival by suppressing mTOR-mediated PP2A-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells. | 2015 Dec |
2 |
| 15 |
24451985 | Stimulatory Effect of Vascular Endothelial Growth Factor on Proliferation and Migration of Porcine Trophectoderm Cells and Their Regulation by the Phosphatidylinositol-3-Kinase-AKT and Mitogen-Activated Protein Kinase Cell Signaling Pathways. | 2014 Mar |
1 |
| 16 |
24516119 | Rapamycin antagonizes TNF induction of VCAM-1 on endothelial cells by inhibiting mTORC2. | 2014 Mar 10 |
3 |
| 17 |
24676456 | The combination of rapamycin and MAPK inhibitors enhances the growth inhibitory effect on Nara-H cells. | 2014 Jun |
2 |
| 18 |
23928863 | Sirolimus stimulates vascular stem/progenitor cell migration and differentiation into smooth muscle cells via epidermal growth factor receptor/extracellular signal-regulated kinase/β-catenin signaling pathway. | 2013 Oct |
2 |
| 19 |
24012499 | Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells. | 2013 Dec |
2 |
| 20 |
22057915 | Rapamycin induces Bad phosphorylation in association with its resistance to human lung cancer cells. | 2012 Jan |
3 |
| 21 |
22552366 | Simultaneous targeting of EGFR and mTOR inhibits the growth of colorectal carcinoma cells. | 2012 Jul |
1 |
| 22 |
21880834 | TGF-β1 mediates sirolimus and cyclosporine A-induced alteration of barrier function in renal epithelial cells via a noncanonical ERK1/2 signaling pathway. | 2011 Dec |
1 |
| 23 |
19856312 | Rapamycin enhances chemotherapy-induced cytotoxicity by inhibiting the expressions of TS and ERK in gastric cancer cells. | 2010 Jun 1 |
1 |
| 24 |
20485667 | Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway. | 2010 May 11 |
4 |
| 25 |
18759859 | Adenovirus-mediated FKBP12.6 overexpression induces hypertrophy and apoptosis in cultured neonatal cardiomyocytes. | 2009 Feb |
1 |
| 26 |
19151764 | Rapamycin induces transactivation of the EGFR and increases cell survival. | 2009 Mar 5 |
3 |
| 27 |
19188252 | Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis. | 2009 Apr 1 |
1 |
| 28 |
19996130 | Inhibition of mTOR Activates the MAPK Pathway in Glioblastoma Multiforme. | 2009 Sep-Oct |
2 |
| 29 |
18374093 | Rapamycin impairs beta-cell proliferation in vivo. | 2008 Mar |
1 |
| 30 |
18425342 | Constitutive activation of p70 S6 kinase is associated with intrinsic resistance to cisplatin. | 2008 May |
1 |
| 31 |
19020771 | Maturation-induced down-regulation of MFG-E8 impairs apoptotic cell clearance and enhances endotoxin response. | 2008 Dec |
1 |
| 32 |
17549426 | Molecular impacts of rapamycin-based drug combinations: combining rapamycin with gemcitabine or imatinib mesylate (Gleevec) in a human leiomyosarcoma model. | 2007 Jul |
1 |
| 33 |
15696050 | Sphingosine-1-phosphate-induced smooth muscle cell migration involves the mammalian target of rapamycin. | 2005 Jan |
1 |
| 34 |
15715661 | Mechanism of zinc-induced phosphorylation of p70 S6 kinase and glycogen synthase kinase 3beta in SH-SY5Y neuroblastoma cells. | 2005 Mar |
1 |
| 35 |
16342424 | Angiotensin IV enhances phosphorylation of 4EBP1 by multiple signaling events in lung endothelial cells. | 2005 Jul |
1 |
| 36 |
12543789 | Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways. | 2003 Jan 15 |
2 |
| 37 |
12225947 | Activation of multiple signaling modules is critical in angiotensin IV-induced lung endothelial cell proliferation. | 2002 Oct |
1 |
| 38 |
11241670 | The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells. | 2001 Mar 26 |
2 |
| 39 |
11319875 | Flow-induced DNA synthesis requires signaling to a translational control pathway. | 2001 May 1 |
1 |