| 1 |
33130276 | P2Y2 receptor activation promotes esophageal cancer cells proliferation via ERK1/2 pathway. | 2021 Jan 15 |
1 |
| 2 |
33273059 | AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib. | 2021 Feb |
1 |
| 3 |
33536188 | ERK Inhibitor LY3214996-Based Treatment Strategies for RAS-Driven Lung Cancer. | 2021 Apr |
1 |
| 4 |
34020277 | Synthesis, biological evaluation and molecular docking studies of novel 1,2,3-triazole-quinazolines as antiproliferative agents displaying ERK inhibitory activity. | 2021 Aug |
1 |
| 5 |
32540611 | P2Y2 receptors mediate nucleotide-induced EGFR phosphorylation and stimulate proliferation and tumorigenesis of head and neck squamous cell carcinoma cell lines. | 2020 Jun 12 |
1 |
| 6 |
32941855 | ATP and ADP enhance DNA damage repair in γ-irradiated BEAS-2B human bronchial epithelial cells through activation of P2X7 and P2Y12 receptors. | 2020 Nov 15 |
3 |
| 7 |
30903640 | A novel interleukin-13 receptor alpha 2-targeted hybrid peptide for effective glioblastoma therapy. | 2019 Jul |
1 |
| 8 |
30909368 | Complementary Role of P2 and Adenosine Receptors in ATP Induced-Anti-Apoptotic Effects Against Hypoxic Injury of HUVECs. | 2019 Mar 22 |
2 |
| 9 |
30942462 | Isobavachalcone exerts anti‑proliferative and pro‑apoptotic effects on human liver cancer cells by targeting the ERKs/RSK2 signaling pathway. | 2019 Jun |
1 |
| 10 |
31159832 | The m6A-suppressed P2RX6 activation promotes renal cancer cells migration and invasion through ATP-induced Ca2+ influx modulating ERK1/2 phosphorylation and MMP9 signaling pathway. | 2019 Jun 3 |
1 |
| 11 |
31266368 | Effects of ATP-competitive and function-selective ERK inhibitors on airway smooth muscle cell proliferation. | 2019 Oct |
3 |
| 12 |
29415987 | Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth. | 2018 Feb 7 |
2 |
| 13 |
29589904 | Engineering a Dual Small Molecule Gated ZAP70 Switch in T Cells. | 2018 Apr 20 |
1 |
| 14 |
29683976 | Activating P2X7 Receptors Increases Proliferation of Human Pancreatic Cancer Cells via ERK1/2 and JNK. | 2018 May/Jun |
4 |
| 15 |
29906487 | Deferoxamine suppresses esophageal squamous cell carcinoma cell growth via ERK1/2 mediated mitochondrial dysfunction. | 2018 Sep 28 |
1 |
| 16 |
30231482 | ATP-Induced Increase in Intracellular Calcium Levels and Subsequent Activation of mTOR as Regulators of Skeletal Muscle Hypertrophy. | 2018 Sep 18 |
1 |
| 17 |
26961545 | CD40 Negatively Regulates ATP-TLR4-Activated Inflammasome in Microglia. | 2017 Mar |
1 |
| 18 |
27696674 | Clarifying binding difference of ATP and ADP to extracellular signal-regulated kinase 2 by using molecular dynamics simulations. | 2017 Apr |
7 |
| 19 |
28445005 | Proteomic-based investigations on the mode of action of the marine anticancer compound rhizochalinin. | 2017 Jun |
3 |
| 20 |
28939558 | Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib). | 2017 Nov |
1 |
| 21 |
26774343 | Kazinol-E is a specific inhibitor of ERK that suppresses the enrichment of a breast cancer stem-like cell population. | 2016 Feb 5 |
1 |
| 22 |
27242443 | ATP Released by Injured Neurons Activates Schwann Cells. | 2016 |
1 |
| 23 |
27364553 | Rebound Effects Caused by Withdrawal of MET Kinase Inhibitor Are Quenched by a MET Therapeutic Antibody. | 2016 Sep 1 |
1 |
| 24 |
25183652 | Adenosine triphosphate prevents serum deprivation-induced apoptosis in human mesenchymal stem cells via activation of the MAPK signaling pathways. | 2015 Jan |
5 |
| 25 |
25695333 | Small-molecule inhibitors of ERK-mediated immediate early gene expression and proliferation of melanoma cells expressing mutated BRaf. | 2015 May 1 |
1 |
| 26 |
26182292 | P2Y2 Receptor and EGFR Cooperate to Promote Prostate Cancer Cell Invasion via ERK1/2 Pathway. | 2015 |
4 |
| 27 |
26372812 | Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells. | 2015 Oct 13 |
1 |
| 28 |
24031026 | Targeting of magnolin on ERKs inhibits Ras/ERKs/RSK2-signaling-mediated neoplastic cell transformation. | 2014 Feb |
1 |
| 29 |
24623131 | Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function. | 2014 Apr 15 |
1 |
| 30 |
25043721 | Contribution of sodium channels to lamellipodial protrusion and Rac1 and ERK1/2 activation in ATP-stimulated microglia. | 2014 Dec |
5 |
| 31 |
25118288 | Shock wave treatment enhances cell proliferation and improves wound healing by ATP release-coupled extracellular signal-regulated kinase (ERK) activation. | 2014 Sep 26 |
1 |
| 32 |
23410953 | Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds. | 2013 Jun |
1 |
| 33 |
23847348 | ERK pathway inhibitors: how low should we go? | 2013 Jul |
1 |
| 34 |
23878142 | C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation. | 2013 Nov 14 |
1 |
| 35 |
24235127 | The C3a receptor, caspase-1, and release of IL-1β. | 2013 Nov 14 |
4 |
| 36 |
22224416 | Adenosine-5'-triphosphate up-regulates proliferation of human cardiac fibroblasts. | 2012 Jun |
1 |
| 37 |
22316156 | Computational insights for the discovery of non-ATP competitive inhibitors of MAP kinases. | 2012 |
1 |
| 38 |
20722064 | The stress signal extracellular ATP modulates antiflagellin immune responses in intestinal epithelial cells. | 2011 Jan |
2 |
| 39 |
21413023 | HB-EGF synthesis and release induced by cholesterol depletion of human epidermal keratinocytes is controlled by extracellular ATP and involves both p38 and ERK1/2 signaling pathways. | 2011 Jun |
1 |
| 40 |
21503959 | P2Y11 impairs cell proliferation by induction of cell cycle arrest and sensitizes endothelial cells to cisplatin-induced cell death. | 2011 Sep |
2 |
| 41 |
21505453 | A role for nucleotides in support of breast cancer angiogenesis: heterologous receptor signalling. | 2011 May 10 |
1 |
| 42 |
21669399 | ATP-mediated Erk1/2 activation stimulates bacterial capture by filopodia, which precedes Shigella invasion of epithelial cells. | 2011 Jun 16 |
2 |
| 43 |
19699794 | Activation of ERK1/2 by protein kinase C-alpha in response to hydrogen peroxide-induced cell death in human gingival fibroblasts. | 2010 Feb |
1 |
| 44 |
20199215 | Involvement of purinergic signaling in cellular response to gamma radiation. | 2010 Mar |
1 |
| 45 |
20562007 | Signal transduction pathways associated with ATP-induced proliferation of colon adenocarcinoma cells. | 2010 Sep |
6 |
| 46 |
20798496 | Higher concentrations of extracellular ATP suppress proliferation of Caco-2 human colonic cancer cells via an unknown receptor involving PKC inhibition. | 2010 |
1 |
| 47 |
18658095 | ERK1/2 mediate wounding- and G-protein-coupled receptor ligands-induced EGFR activation via regulating ADAM17 and HB-EGF shedding. | 2009 Jan |
2 |
| 48 |
19386603 | ATP-mediated activation of the NADPH oxidase DUOX1 mediates airway epithelial responses to bacterial stimuli. | 2009 Jun 26 |
2 |
| 49 |
19836435 | Extracellular ATP activates MAP kinase cascades through a P2Y purinergic receptor in the human intestinal Caco-2 cell line. | 2009 Dec |
1 |
| 50 |
18434089 | Extracellular ATP activates the PLC/PKC/ERK signaling pathway through the P2Y2 purinergic receptor leading to the induction of early growth response 1 expression and the inhibition of viability in human endometrial stromal cells. | 2008 Jul |
5 |