Nicotine

mitogen-activated protein kinase 3 ; Homo sapiens







34 Article(s)
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1 34890707 Nicotine stimulates IL-8 expression via ROS/NF-κB and ROS/MAPK/AP-1 axis in human gastric cancer cells. 2022 Jan 30 1
2 35563563 Sulforaphane Suppresses the Nicotine-Induced Expression of the Matrix Metalloproteinase-9 via Inhibiting ROS-Mediated AP-1 and NF-κB Signaling in Human Gastric Cancer Cells. 2022 May 5 1
3 33355840 Changes in Mucin Production in Human Airway Epithelial Cells After Exposure to Electronic Cigarette Vapor With or Without Nicotine. 2021 Aug 1
4 33662786 Nicotine-derived NNK induces the stemness enrichment of CRC cells through regulating the balance of DUSP4-ERK1/2 feedback loop. 2021 May 1
5 34006831 Nicotine aggravates vascular adiponectin resistance via ubiquitin-mediated adiponectin receptor degradation in diabetic Apolipoprotein E knockout mouse. 2021 May 18 1
6 32361056 An okadaic acid fragment analogue prevents nicotine-induced resistance to cisplatin by recovering PP2A activity in non-small cell lung cancer cells. 2020 Jul 3
7 29486207 nAChRs-ERK1/2-Egr-1 signaling participates in the developmental toxicity of nicotine by epigenetically down-regulating placental 11β-HSD2. 2018 Apr 1 3
8 29715455 Regulatory effect of nicotine on the differentiation of Th1, Th2 and Th17 lymphocyte subsets in patients with rheumatoid arthritis. 2018 Jul 15 1
9 28890319 Arctic Aβ40 blocks the nicotine-induced neuroprotective effect of CHRNA7 by inhibiting the ERK1/2 pathway in human neuroblastoma cells. 2017 Nov 3
10 29017931 Acute nicotine disrupts consolidation of contextual fear extinction and alters long-term memory-associated hippocampal kinase activity. 2017 Nov 2
11 26530054 Nicotine enhances invasion and metastasis of human colorectal cancer cells through the nicotinic acetylcholine receptor downstream p38 MAPK signaling pathway. 2016 Jan 1
12 27907022 Nicotine Induces Podocyte Apoptosis through Increasing Oxidative Stress. 2016 2
13 24481039 Nicotine exerts neuroprotective effects against β-amyloid-induced neurotoxicity in SH-SY5Y cells through the Erk1/2-p38-JNK-dependent signaling pathway. 2014 Apr 5
14 24793809 α5 Nicotinic acetylcholine receptor mediates nicotine-induced HIF-1α and VEGF expression in non-small cell lung cancer. 2014 Jul 15 1
15 21070506 ERK1/2 protein and mRNA levels in human blood are linked to smoking behavior. 2012 Nov 2
16 22520577 Nicotine stimulates proliferation and inhibits apoptosis in colon cancer cell lines through activation of survival pathways. 2012 Nov 1
17 22952803 Nicotine promotes proliferation of human nasopharyngeal carcinoma cells by regulating α7AChR, ERK, HIF-1α and VEGF/PEDF signaling. 2012 2
18 23149874 Nicotine induces the expression of C-reactive protein via MAPK-dependent signal pathway in U937 macrophages. 2012 Nov 1
19 21781517 [Interaction of protein kinase C-extracellular signal-regulated kinase 1/2 signal pathway in the process of plasminogen activator inhibitor-1 expression induced by nicotine in human umbilical vein endothelial cells]. 2011 Jun 2
20 22085699 Sensitization of epithelial growth factor receptors by nicotine exposure to promote breast cancer cell growth. 2011 1
21 20106947 Long-term nicotine exposure-induced chemoresistance is mediated by activation of Stat3 and downregulation of ERK1/2 via nAChR and beta-adrenoceptors in human bladder cancer cells. 2010 May 2
22 19358273 Induction of osteopontin expression by nicotine and cigarette smoke in the pancreas and pancreatic ductal adenocarcinoma cells. 2009 Jul 15 2
23 19903766 Nicotine enhances the antiapoptotic function of Mcl-1 through phosphorylation. 2009 Dec 1
24 18448488 Rapid activation of Stat3 and ERK1/2 by nicotine modulates cell proliferation in human bladder cancer cells. 2008 Aug 3
25 17003101 Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. 2007 Mar 4
26 17459420 Nitrosamines as nicotinic receptor ligands. 2007 May 30 2
27 16257255 Nicotine stimulates adhesion molecular expression via calcium influx and mitogen-activated protein kinases in human endothelial cells. 2006 Feb 4
28 16644474 Estrogen down-regulates nicotine-induced adhesion molecule expression via nongenomic signal pathway in endothelial cells. 2006 Jun 3
29 16716121 Mitogen-activated protein kinase pathway was significantly activated in human bronchial epithelial cells by nicotine. 2006 May 4
30 17168719 Development of novel therapeutic strategies for lung cancer: targeting the cholinergic system. 2006 1
31 15813854 Nicotinic acetylcholine receptor-mediated stimulation of endothelial cells results in the arrest of haematopoietic progenitor cells on endothelium. 2005 Apr 1
32 15037618 Nicotine induces multi-site phosphorylation of Bad in association with suppression of apoptosis. 2004 May 28 3
33 12421819 A functional role for nicotine in Bcl2 phosphorylation and suppression of apoptosis. 2003 Jan 17 1
34 11905997 Nicotine activates the extracellular signal-regulated kinase 1/2 via the alpha7 nicotinic acetylcholine receptor and protein kinase A, in SH-SY5Y cells and hippocampal neurones. 2002 Feb 3