Lithocholic Acid

nuclear receptor subfamily 1 group I member 2 ; Homo sapiens







17 Article(s)
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1 31336134 Lignans from Schisandra sphenanthera protect against lithocholic acid-induced cholestasis by pregnane X receptor activation in mice. 2019 Dec 5 2
2 25808545 Microbial-derived lithocholic acid and vitamin K2 drive the metabolic maturation of pluripotent stem cells-derived and fetal hepatocytes. 2015 Jul 2
3 22561792 Involvement of multiple elements in FXR-mediated transcriptional activation of FGF19. 2012 Oct 4
4 20888898 The role of lithocholic acid in the regulation of bile acid detoxication, synthesis, and transport proteins in rat and human intestine and liver slices. 2011 Feb 1
5 21977915 Expression, localization and polymorphisms of the nuclear receptor PXR in Barrett's esophagus and esophageal adenocarcinoma. 2011 Oct 6 2
6 18537536 Bile acids and derivatives, their nuclear receptors FXR, PXR and ligands: role in health and disease and their therapeutic potential. 2008 Jun 2
7 18800312 Sequencing and functional assessment of hPXR (NR1I2) variants in intrahepatic cholestasis of pregnancy. 2008 Oct 1
8 17327420 Crystal structure of the pregnane X receptor-estradiol complex provides insights into endobiotic recognition. 2007 May 2
9 17491508 Coordinated defence and the liver. 2007 Apr 6
10 17696253 Lithocholic acid induction of the FGF19 promoter in intestinal cells is mediated by PXR. 2007 Aug 21 5
11 15883047 Pregnane X receptor-agonists down-regulate hepatic ATP-binding cassette transporter A1 and scavenger receptor class B type I. 2005 Jun 17 1
12 14525957 Structural determinants for vitamin D receptor response to endocrine and xenobiotic signals. 2004 Jan 1
13 15515100 Modified oligonucleotides containing lithocholic acid in their backbones: their enhanced cellular uptake and their mimicking of hairpin structures. 2004 Nov 5 2
14 11893771 Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor. 2002 Mar 6
15 12370413 Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR). 2002 Oct 15 5
16 11248085 The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. 2001 Mar 13 5
17 11248086 An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. 2001 Mar 13 2