Hydrogen Peroxide

AKT serine/threonine kinase 1 ; Rattus norvegicus







142 Article(s)
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101 21478407 H2O2 preconditioning modulates phase II enzymes through p38 MAPK and PI3K/Akt activation. 2011 Jun 2
102 21563965 Salidroside protects against hydrogen peroxide-induced injury in cardiac H9c2 cells via PI3K-Akt dependent pathway. 2011 Oct 1
103 21751224 Signal transduction pathways through cytoprotective, apoptotic and hypertrophic stimuli: a comparative study in adult cardiac myocytes. 2011 Aug 1
104 21874266 Hydrogen peroxide controls Akt activity via ubiquitination/degradation pathways. 2011 Dec 6
105 20139898 Hydrogen peroxide stress stimulates phosphorylation of FoxO1 in rat aortic endothelial cells. 2010 Feb 1
106 20152804 Brief exposure to carbon monoxide preconditions cardiomyogenic cells against apoptosis in ischemia-reperfusion. 2010 Mar 12 1
107 20643227 Pharmacological inhibition of Axl affects smooth muscle cell functions under oxidative stress. 2010 Sep-Oct 2
108 19033378 Ethanol prevents oxidant-induced mitochondrial permeability transition pore opening in cardiac cells. 2009 Jan-Feb 1
109 19218529 Pharmacological preconditioning of mesenchymal stem cells with trimetazidine (1-[2,3,4-trimethoxybenzyl]piperazine) protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 expression. 2009 May 1
110 19222219 Modulation of Akt, JNK, and p38 activation is involved in citrus flavonoid-mediated cytoprotection of PC12 cells challenged by hydrogen peroxide. 2009 Mar 25 1
111 19703415 Propofol protects against hydrogen peroxide-induced injury in cardiac H9c2 cells via Akt activation and Bcl-2 up-regulation. 2009 Nov 6 3
112 18338802 Bilirubin as an endogenous modulator of neurotrophin redox signaling. 2008 Aug 1 1
113 18387957 Differential modulation of Akt/glycogen synthase kinase-3beta pathway regulates apoptotic and cytoprotective signaling responses. 2008 May 30 2
114 18410586 Melatonin represses oxidative stress-induced activation of the MAP kinase and mTOR signaling pathways in H4IIE hepatoma cells through inhibition of Ras. 2008 May 3
115 18552162 Factors released from embryonic stem cells inhibit apoptosis in H9c2 cells through PI3K/Akt but not ERK pathway. 2008 Aug 1
116 18599524 Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme 8-oxo-7,8-dihydro-2'-deoxyguanosine-DNA glycosylase. 2008 Oct 1
117 18775681 15-Deoxy-Delta(12,14)-prostaglandin J(2) rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: potential roles of Akt and ERK1/2. 2008 Dec 1 1
118 18787053 The role of redox signaling in cardiac hypertrophy induced by experimental hyperthyroidism. 2008 Dec 1
119 18981661 Indole-3-carbinol prevents H(2)O(2)-induced inhibition of gap junctional intercellular communication by inactivation of PKB/Akt. 2008 Oct 3
120 19033821 Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function. 2008 Nov 1
121 17213958 Nerve growth factor prevents the apoptosis-associated increase in acetylcholinesterase activity after hydrogen peroxide treatment by activating Akt. 2007 Jan 2
122 17559808 Angiopoietin-1 protects H9c2 cells from H2O2-induced apoptosis through AKT signaling. 2007 Aug 3 1
123 18091994 Salvianolic acid B inhibits hydrogen peroxide-induced endothelial cell apoptosis through regulating PI3K/Akt signaling. 2007 Dec 19 4
124 18167217 Heat shock protein 27 regulates oxidative stress-induced apoptosis in cardiomyocytes: mechanisms via reactive oxygen species generation and Akt activation. 2007 Dec 20 1
125 16549430 17Beta-estradiol protects against oxidative stress-induced cell death through the glutathione/glutaredoxin-dependent redox regulation of Akt in myocardiac H9c2 cells. 2006 May 12 1
126 16999977 IGF-1 protects intestinal epithelial cells from oxidative stress-induced apoptosis. 2006 Nov 1
127 15637121 Angiotensin II-induced Akt activation is mediated by metabolites of arachidonic acid generated by CaMKII-stimulated Ca2(+)-dependent phospholipase A2. 2005 May 1
128 15705590 Implication of phospholipase D2 in oxidant-induced phosphoinositide 3-kinase signaling via Pyk2 activation in PC12 cells. 2005 Apr 22 2
129 15710234 Protective effect of diallyl disulfide on oxidative stress-injured neuronally differentiated PC12 cells. 2005 Feb 18 1
130 15871910 Stepholidine protects against H2O2 neurotoxicity in rat cortical neurons by activation of Akt. 2005 Aug 5 1
131 15904668 Preincubation with sodium ascorbate potentiates insulin-dependent PKB/Akt and c-Jun phosphorylation in L6 rat myoblasts challenged with reactive oxygen/nitrogen species. 2005 Jun 17 4
132 15317858 Regulation of Cu/Zn-superoxide dismutase expression via the phosphatidylinositol 3 kinase/Akt pathway and nuclear factor-kappaB. 2004 Aug 18 1
133 15385548 Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling. 2004 Dec 3 1
134 12788379 H(2)O(2) regulates cardiac myocyte phenotype via concentration-dependent activation of distinct kinase pathways. 2003 Jun 2
135 14522978 Glutaredoxin exerts an antiapoptotic effect by regulating the redox state of Akt. 2003 Dec 12 4
136 14622133 Signalling pathways influencing basal and H(2)O(2)-induced P-glycoprotein expression in endothelial cells derived from the blood-brain barrier. 2003 Nov 1
137 11709495 Loss in oxidative stress tolerance with aging linked to reduced extracellular signal-regulated kinase and Akt kinase activities. 2002 Jan 2
138 12472888 Induction of heat shock proteins (HSPs) by sodium arsenite in cultured astrocytes and reduction of hydrogen peroxide-induced cell death. 2002 Dec 2
139 11228094 Insulin-like growth factor-1 protects H9c2 cardiac myoblasts from oxidative stress-induced apoptosis via phosphatidylinositol 3-kinase and extracellular signal-regulated kinase pathways. 2001 Jan 26 2
140 11368352 Induction of Akt phosphorylation in rat primary astrocytes by H2O2 occurs upstream of phosphatidylinositol 3-kinase: no evidence for oxidative inhibition of PTEN. 2001 Feb 15 6
141 11602326 Alpha-lipoic acid protects rat cortical neurons against cell death induced by amyloid and hydrogen peroxide through the Akt signalling pathway. 2001 Oct 26 1
142 11033117 Growth factor-induced phosphoinositide 3-OH kinase/Akt phosphorylation in smooth muscle cells: induction of cell proliferation and inhibition of cell death. 2000 Oct 3