alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide

signal transducer and activator of transcription 3 ; Rattus norvegicus







55 Article(s)
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1 35248926 JAK2/STAT3 pathway regulates microglia polarization involved in hippocampal inflammatory damage due to acute paraquat exposure. 2022 Mar 3 2
2 35465093 Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines. 2022 1
3 33816486 Knockout of NOS2 Promotes Adipogenic Differentiation of Rat MSCs by Enhancing Activation of JAK/STAT3 Signaling. 2021 1
4 33968620 The interplay between HIF-1α and long noncoding GAS5 regulates the JAK1/STAT3 signalling pathway in hypoxia-induced injury in myocardial cells. 2021 Apr 2
5 34335747 PERK-Dependent Activation of the JAK2/STAT3 Pathway Contributes to High Glucose-Induced Extracellular Matrix Deposition in Renal Tubular Epithelial Cells. 2021 1
6 31853718 Resveratrol Downregulates STAT3 Expression and Astrocyte Activation in Primary Astrocyte Cultures of Rat. 2020 Feb 1
7 31926201 Activating α7nAChRs enhances endothelial progenitor cell function partially through the JAK2/STAT3 signaling pathway. 2020 May 1
8 32427806 microRNA-1906 protects cerebral ischemic injury through activating Janus kinase 2/signal transducer and activator of transcription 3 pathway in rats. 2020 Aug 12 2
9 32673665 JLX001 improves myocardial ischemia-reperfusion injury by activating Jak2-Stat3 pathway. 2020 Sep 15 1
10 32688030 Astrocytic NDRG2 is critical in the maintenance of neuropathic pain. 2020 Oct 1
11 32711244 Fucoidan from Fucus vesiculosus attenuates doxorubicin-induced acute cardiotoxicity by regulating JAK2/STAT3-mediated apoptosis and autophagy. 2020 Oct 1
12 32720796 MiR-29c-3p inhibits proliferation and migration in rat primary cardiac fibroblasts via interacting with STAT3. 2020 Jul 27 1
13 33384595 Anisodamine Maintains the Stability of Intervertebral Disc Tissue by Inhibiting the Senescence of Nucleus Pulposus Cells and Degradation of Extracellular Matrix via Interleukin-6/Janus Kinases/Signal Transducer and Activator of Transcription 3 Pathway. 2020 1
14 33519417 Dl-3-n-Butylphthalide Alleviates Hippocampal Neuron Damage in Chronic Cerebral Hypoperfusion via Regulation of the CNTF/CNTFRα/JAK2/STAT3 Signaling Pathways. 2020 1
15 30657573 Effect of the JAK2/STAT3 signaling pathway on nerve cell apoptosis in rats with white matter injury. 2019 Jan 1
16 30913399 STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy. 2019 Jul 1
17 31463567 Cardioprotection of post-ischemic moderate ROS against ischemia/reperfusion via STAT3-induced the inhibition of MCU opening. 2019 Aug 28 1
18 30070334 Role of Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway in cardioprotection of exercise preconditioning. 2018 Aug 1
19 30649810 Activation of signal transducer and activator of transcription 3 signaling attenuates neurogenesis in a rat model of intracerebral hemorrhage. 2018 Sep 3 1
20 27848055 Knockdown of KLF11 attenuates hypoxia/reoxygenation injury via JAK2/STAT3 signaling in H9c2. 2017 Apr 1
21 27998796 Propofol postconditioning attenuates hippocampus ischemia-reperfusion injury via modulating JAK2/STAT3 pathway in rats after autogenous orthotropic liver transplantation. 2017 Feb 15 2
22 29039526 Promoting effects of IL‑23 on myocardial ischemia and reperfusion are associated with increased expression of IL‑17A and upregulation of the JAK2‑STAT3 signaling pathway. 2017 Dec 1
23 29210652 Inhibition of JAK2 Signaling Alleviates Hyperlipidemia-Intensified Caerulin-Induced Acute Pancreatitis In Vivo. 2017 1
24 26487394 Combined administration of propranolol + AG490 offers better effects on portal hypertensive rats with cirrhosis. 2016 May 2
25 26806299 Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress. 2016 Mar 2
26 27064043 Interleukin-10 Contributes to Therapeutic Effect of Mesenchymal Stem Cells for Acute Liver Failure via Signal Transducer and Activator of Transcription 3 Signaling Pathway. 2016 Apr 20 2
27 27301615 Catalpol stimulates VEGF production via the JAK2/STAT3 pathway to improve angiogenesis in rats' stroke model. 2016 Sep 15 1
28 25637451 Inhibition of Janus kinase-2 signalling pathway ameliorates portal hypertensive syndrome in partial portal hypertensive and liver cirrhosis rats. 2015 Apr 1
29 25796004 Elatoside C protects the heart from ischaemia/reperfusion injury through the modulation of oxidative stress and intracellular Ca²⁺ homeostasis. 2015 Apr 15 1
30 26261556 JAK2/STAT3 pathway mediating inflammatory responses in heatstroke-induced rats. 2015 1
31 26628981 Curcumin protects against cerebral ischemia-reperfusion injury by activating JAK2/STAT3 signaling pathway in rats. 2015 1
32 26739468 [Reversal of liver fibrosis through AG490 inhibitor-mediated inhibition of the TGFbeta1-STAT3 pathway]. 2015 Dec 1
33 24300830 The synthetic pentasaccharide fondaparinux attenuates myocardial ischemia-reperfusion injury in rats via STAT-3. 2014 Feb 1
34 24836854 Aspirin-triggered Lipoxin A4 attenuates mechanical allodynia in association with inhibiting spinal JAK2/STAT3 signaling in neuropathic pain in rats. 2014 Jul 25 1
35 25088002 P300-dependent STAT3 acetylation is necessary for angiotensin II-induced pro-fibrotic responses in renal tubular epithelial cells. 2014 Sep 1
36 25105067 Propofol mediates signal transducer and activator of transcription 3 activation and crosstalk with phosphoinositide 3-kinase/AKT. 2014 1
37 23383203 Novel mechanism of inhibition of dendritic cells maturation by mesenchymal stem cells via interleukin-10 and the JAK1/STAT3 signaling pathway. 2013 1
38 23759023 Dexmedetomidine protects against renal ischemia and reperfusion injury by inhibiting the JAK/STAT signaling activation. 2013 Jun 9 1
39 23764464 SMND-309, a novel derivative of salvianolic acid B, protects rat brains ischemia and reperfusion injury by targeting the JAK2/STAT3 pathway. 2013 Aug 15 1
40 24055641 Red ginseng extract inhibits the expression of MCP-1 and iNOS in Helicobacter pylori-infected gastric epithelial cells by suppressing the activation of NADPH oxidase and Jak2/Stat3. 2013 Nov 25 1
41 22285838 High glucose enhances TGF-β1 expression in rat bone marrow stem cells via ERK1/2-mediated inhibition of STAT3 signaling. 2012 Apr 9 2
42 22431190 Interleukin 6 protects H(2)O(2)-induced cardiomyocytes injury through upregulation of prohibitin via STAT3 phosphorylation. 2012 Jul 2
43 24058756 Angiotensin II induces cell growth and IL-6 mRNA expression through the JAK2-STAT3 pathway in rat cerebellar astrocytes. 2012 Apr 1 1
44 21470923 Activation of a pro-survival pathway IL-6/JAK2/STAT3 contributes to glial fibrillary acidic protein induction during the cholera toxin-induced differentiation of C6 malignant glioma cells. 2011 Jun 1
45 21525184 Reactive oxygen species scavenger inhibits STAT3 activation after transient focal cerebral ischemia-reperfusion injury in rats. 2011 Jul 1
46 19640900 Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy. 2009 Oct 1
47 18636982 JAK/STAT3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat. 2008 Oct 1
48 18710787 JAK2-STAT3 signaling pathway mediates thrombin-induced proinflammatory actions of microglia in vitro. 2008 Nov 15 1
49 16923154 JAK2 and STAT3 activation contributes to neuronal damage following transient focal cerebral ischemia. 2006 Sep 1
50 16344382 Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase). 2005 Dec 20 1