acadesine

protein kinase AMP-activated catalytic subunit alpha 1 ; Homo sapiens







55 Article(s)
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1 34727932 Medium & long-chain acylcarnitine's relation to lipid metabolism as potential predictors for diabetic cardiomyopathy: a metabolomic study. 2021 Nov 2 2
2 32898618 Effects of treadmill exercise on the regulation of tight junction proteins in aged mice. 2020 Nov 2
3 32986917 CCAL1 enhances osteoarthritis through the NF-κB/AMPK signaling pathway. 2020 Dec 2
4 33002460 Artesunate induces autophagy dependent apoptosis through upregulating ROS and activating AMPK-mTOR-ULK1 axis in human bladder cancer cells. 2020 Nov 1 1
5 30468782 Metabolomics profiling of metformin-mediated metabolic reprogramming bypassing AMPKα. 2019 Feb 1
6 31431503 The ribonucleoside AICAr induces differentiation of myeloid leukemia by activating the ATR/Chk1 via pyrimidine depletion. 2019 Oct 18 2
7 29546577 Urine levels of 5-aminoimidazole-4-carboxamide riboside (AICAR) in patients with type 2 diabetes. 2018 Jun 2
8 29688769 IL6 and LIF mRNA expression in skeletal muscle is regulated by AMPK and the transcription factors NFYC, ZBTB14, and SP1. 2018 Nov 1 1
9 29773845 AICAR inhibits NFκB DNA binding independently of AMPK to attenuate LPS-triggered inflammatory responses in human macrophages. 2018 May 17 2
10 30002135 Opposing effects of intracellular versus extracellular adenine nucleotides on autophagy: implications for β-cell function. 2018 Aug 6 2
11 30251691 Alpha-lipoic acid regulates the autophagy of vascular smooth muscle cells in diabetes by elevating hydrogen sulfide level. 2018 Nov 1
12 28174693 Fanconi anemia protein FANCD2 is activated by AICAR, a modulator of AMPK and cellular energy metabolism. 2017 Feb 2
13 28445821 The AMPK/mTOR pathway is involved in D-dopachrome tautomerase gene transcription in adipocytes differentiated from SGBS cells, a human preadipocyte cell line. 2017 Aug 4
14 28556920 AMPK activator acadesine fails to alleviate isoniazid-caused mitochondrial instability in HepG2 cells. 2017 Oct 1
15 28978086 AMPK activation-dependent autophagy compromises oleanolic acid-induced cytotoxicity in human bladder cancer cells. 2017 Sep 15 1
16 26614120 Regulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation. 2016 Feb 1 2
17 27062501 AMP-activated protein kinase inhibits Kv 1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation. 2016 Sep 1 2
18 27562249 AMPK-independent inhibition of human macrophage ER stress response by AICAR. 2016 Aug 26 1
19 27657826 Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells. 2016 Dec 3
20 25354528 Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cells. 2015 Feb 1 3
21 25428125 AMP-activated protein kinase (AMPK) activation inhibits nuclear translocation of Smad4 in mesangial cells and diabetic kidneys. 2015 May 15 2
22 26194078 Exendin-4 Inhibits the Expression of SEPP1 and Fetuin-A via Improvement of Palmitic Acid-Induced Endoplasmic Reticulum Stress by AMPK. 2015 Jun 2
23 24555415 Activation of AMP-activated protein kinase attenuates hepatocellular carcinoma cell adhesion stimulated by adipokine resistin. 2014 Feb 20 4
24 25315694 Regulation of FSP27 protein stability by AMPK and HSC70. 2014 Dec 1 4
25 25360075 5-aminoimidazole-4-carboxamide Riboside Induces Apoptosis Through AMP-activated Protein Kinase-independent and NADPH Oxidase-dependent Pathways. 2014 Oct 1
26 22704782 Activation of phosphatidylinositol-3 kinase, AMP-activated kinase and Akt substrate-160 kDa by trans-10, cis-12 conjugated linoleic acid mediates skeletal muscle glucose uptake. 2013 Feb 1
27 23525626 β-Lapachone, a substrate of NAD(P)H:quinone oxidoreductase, induces anti-inflammatory heme oxygenase-1 via AMP-activated protein kinase activation in RAW264.7 macrophages. 2013 Mar 1
28 23625915 Store-operated Ca2+ entry (SOCE) induced by protease-activated receptor-1 mediates STIM1 protein phosphorylation to inhibit SOCE in endothelial cells through AMP-activated protein kinase and p38β mitogen-activated protein kinase. 2013 Jun 7 2
29 23863464 AMP-activated protein kinase regulates the vacuolar H+-ATPase via direct phosphorylation of the A subunit (ATP6V1A) in the kidney. 2013 Oct 1 2
30 23019413 Alterations of phosphoproteins in NCI-H526 small cell lung cancer cells involved in cytotoxicity of cisplatin and titanocene Y. 2012 Sep 2
31 21037234 Activation of AMPK stimulates heme oxygenase-1 gene expression and human endothelial cell survival. 2011 Jan 6
32 21217782 LITAF and TNFSF15, two downstream targets of AMPK, exert inhibitory effects on tumor growth. 2011 Apr 21 4
33 20133456 Adenosine 5'-monophosphate-activated protein kinase-mammalian target of rapamycin cross talk regulates brown adipocyte differentiation. 2010 Mar 2
34 20686348 siRNA-mediated AMPKalpha1 subunit gene PRKAA1 silencing enhances methylmercury toxicity in HEK293 cells. 2010 Aug 2
35 19052260 Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells. 2009 Feb 4
36 19261894 Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons. 2009 Mar 4 2
37 19262472 A new constitutively active mutant of AMP-activated protein kinase inhibits anoxia-induced apoptosis of vascular endothelial cell. 2009 Feb 2
38 19347029 Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells. 2009 May 7 1
39 19639604 AMP-activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes. 2009 Oct 1 1
40 16870829 Potentiation of insulin-stimulated glucose transport by the AMP-activated protein kinase. 2007 Jan 1
41 17513706 5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside acutely stimulates skeletal muscle 2-deoxyglucose uptake in healthy men. 2007 Aug 1
42 17603555 Pharmacological activators of AMP-activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells. 2007 Aug 1
43 17617726 AMPK activation stimulates myofibrillar protein degradation and expression of atrophy-related ubiquitin ligases by increasing FOXO transcription factors in C2C12 myotubes. 2007 Jul 1
44 16636195 Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells. 2006 Jun 3
45 15769985 Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabetics. 2005 Jun 1
46 15919715 Phenformin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) activation of AMP-activated protein kinase inhibits transepithelial Na+ transport across H441 lung cells. 2005 Aug 1 4
47 15928020 Activators of AMP-activated protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3-L1 adipocytes. 2005 Oct 2
48 14573616 Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle. 2004 Jan 9 4
49 15009683 AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus. 2004 Mar 7
50 15033479 AICAR stimulates adiponectin and inhibits cytokines in adipose tissue. 2004 Apr 9 1