| 1 |
35112931 | No effect of acute tetrahydrobiopterin (BH4) supplementation on vascular dysfunction in the old. | 2022 Mar 1 |
2 |
| 2 |
35180005 | Endothelial colony forming cells' tetrahydrobiopterin level in coronary artery disease patients and its association with circulating endothelial progenitor cells. | 2022 May |
2 |
| 3 |
35607381 | Naringenin upregulates GTPCH1/eNOS to ameliorate high glucose-induced retinal endothelial cell injury. | 2022 Jun |
2 |
| 4 |
32363908 | Oxidative Stress, GTPCH1, and Endothelial Nitric Oxide Synthase Uncoupling in Hypertension. | 2021 Mar 20 |
3 |
| 5 |
33497797 | How does ascorbate improve endothelial dysfunction? - A computational analysis. | 2021 Mar |
6 |
| 6 |
33548859 | Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia. | 2021 Apr |
10 |
| 7 |
34016263 | Fat-Secreted Ceramides Regulate Vascular Redox State and Influence Outcomes in Patients With Cardiovascular Disease. | 2021 May 25 |
1 |
| 8 |
34118596 | Apolipoprotein A-I mimetic peptide inhibits atherosclerosis by increasing tetrahydrobiopterin via regulation of GTP-cyclohydrolase 1 and reducing uncoupled endothelial nitric oxide synthase activity. | 2021 Jul |
3 |
| 9 |
34356605 | Endothelial Dysfunction Driven by Hypoxia-The Influence of Oxygen Deficiency on NO Bioavailability. | 2021 Jul 3 |
3 |
| 10 |
34502464 | Metastatic Melanoma Progression Is Associated with Endothelial Nitric Oxide Synthase Uncoupling Induced by Loss of eNOS:BH4 Stoichiometry. | 2021 Sep 3 |
5 |
| 11 |
35083247 | Tetrahydrobiopterin Administration Augments Exercise-Induced Hyperemia and Endothelial Function in Patients With Systemic Sclerosis. | 2021 |
5 |
| 12 |
31782159 | Tetrahydrobiopterin Restores Microvascular Dysfunction in Young Adult Binge Drinkers. | 2020 Feb |
2 |
| 13 |
31964986 | CR6-interacting factor 1 deficiency reduces endothelial nitric oxide synthase activity by inhibiting biosynthesis of tetrahydrobiopterin. | 2020 Jan 21 |
1 |
| 14 |
32411442 | Reduced Circulating Endothelial Progenitor Cells and Downregulated GTCPH I Pathway Related to Endothelial Dysfunction in Premenopausal Women with Isolated Impaired Glucose Tolerance. | 2020 |
3 |
| 15 |
32427079 | Nitric Oxide Donors as Potential Drugs for the Treatment of Vascular Diseases Due to Endothelium Dysfunction. | 2020 |
2 |
| 16 |
33182831 | Anti-Vascular Inflammatory Effect of Ethanol Extract from Securinega suffruticosa in Human Umbilical Vein Endothelial Cells. | 2020 Nov 10 |
1 |
| 17 |
30621010 | New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease. | 2019 Jan 7 |
1 |
| 18 |
31040342 | Reduced caveolae density in arteries of SHR contributes to endothelial dysfunction and ROS production. | 2019 Apr 30 |
2 |
| 19 |
31781259 | Far-Infrared-Emitting Sericite Board Upregulates Endothelial Nitric Oxide Synthase Activity through Increasing Biosynthesis of Tetrahydrobiopterin in Endothelial Cells. | 2019 |
1 |
| 20 |
29524646 | Cigarette smoke constituents cause endothelial nitric oxide synthase dysfunction and uncoupling due to depletion of tetrahydrobiopterin with degradation of GTP cyclohydrolase. | 2018 Jun 1 |
1 |
| 21 |
29566572 | Effects Of Endothelin-1 On Intracellular Tetrahydrobiopterin Levels In Vascular Tissue. | 2018 Jun |
2 |
| 22 |
29705218 | Acute Tetrahydrobiopterin Improves Endothelial Function in Patients With COPD. | 2018 Sep |
2 |
| 23 |
28729163 | Computational analysis of interactions of oxidative stress and tetrahydrobiopterin reveals instability in eNOS coupling. | 2017 Nov |
8 |
| 24 |
28980911 | Acute oral tetrahydrobiopterin administration ameliorates endothelial dysfunction in systemic sclerosis. | 2017 Sep-Oct |
2 |
| 25 |
26590088 | Ascorbic acid prevents VEGF-induced increases in endothelial barrier permeability. | 2016 Jan |
1 |
| 26 |
26628675 | Impaired Endothelial Repair Capacity of Early Endothelial Progenitor Cells in Hypertensive Patients With Primary Hyperaldosteronemia: Role of 5,6,7,8-Tetrahydrobiopterin Oxidation and Endothelial Nitric Oxide Synthase Uncoupling. | 2016 Feb |
1 |
| 27 |
26896473 | Tetrahydrobiopterin Supplementation Improves Endothelial Function But Does Not Alter Aortic Stiffness in Patients With Rheumatoid Arthritis. | 2016 Feb 19 |
2 |
| 28 |
27279530 | Downregulation of tetrahydrobiopterin inhibits tumor angiogenesis in BALB/c-nu mice with hepatocellular carcinoma. | 2016 Aug |
2 |
| 29 |
24180387 | Tetrahydrobiopterin regulation of eNOS redox function. | 2014 |
3 |
| 30 |
24333161 | Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies. | 2014 Jan 30 |
2 |
| 31 |
24616589 | Relationship between tetrahydrobiopterin and portal hypertension in patients with chronic liver disease. | 2014 Mar |
2 |
| 32 |
24863258 | Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling. | 2014 Aug 1 |
3 |
| 33 |
23139420 | Integrated redox sensor and effector functions for tetrahydrobiopterin- and glutathionylation-dependent endothelial nitric-oxide synthase uncoupling. | 2013 Jan 4 |
3 |
| 34 |
23395155 | Uncoupling of endothelial NO synthase in atherosclerosis and vascular disease. | 2013 Apr |
2 |
| 35 |
23774601 | The intracellular environment of human macrophages that produce nitric oxide promotes growth of mycobacteria. | 2013 Sep |
1 |
| 36 |
23897679 | Reactive oxygen species in pulmonary vascular remodeling. | 2013 Jul |
2 |
| 37 |
23965989 | A pivotal role for tryptophan 447 in enzymatic coupling of human endothelial nitric oxide synthase (eNOS): effects on tetrahydrobiopterin-dependent catalysis and eNOS dimerization. | 2013 Oct 11 |
9 |
| 38 |
24144633 | Uncoupling of eNOS contributes to redox-sensitive leukocyte recruitment and microvascular leakage elicited by methylglyoxal. | 2013 Dec 15 |
2 |
| 39 |
21093076 | Fluvastatin upregulates endothelial nitric oxide synthase activity via enhancement of its phosphorylation and expression and via an increase in tetrahydrobiopterin in vascular endothelial cells. | 2012 Apr 5 |
1 |
| 40 |
22116695 | Vitamin C in sepsis. | 2012 |
2 |
| 41 |
22245769 | Tetrahydrobiopterin improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women. | 2012 Mar 1 |
1 |
| 42 |
22542797 | Ascorbate stimulates endothelial nitric oxide synthase enzyme activity by rapid modulation of its phosphorylation status. | 2012 May 15 |
6 |
| 43 |
22586583 | Uncoupling endothelial nitric oxide synthase is ameliorated by green tea in experimental diabetes by re-establishing tetrahydrobiopterin levels. | 2012 Jul |
1 |
| 44 |
22929836 | Detection of nitric oxide and superoxide radical anion by electron paramagnetic resonance spectroscopy from cells using spin traps. | 2012 Aug 18 |
2 |
| 45 |
21178821 | Tetrahydrobiopterin is present in high quantity in human milk and has a vasorelaxing effect on newborn rat mesenteric arteries. | 2011 Apr |
1 |
| 46 |
21458460 | Targeting endothelial and myocardial dysfunction with tetrahydrobiopterin. | 2011 Oct |
1 |
| 47 |
21664268 | Vitamins C and E: beneficial effects from a mechanistic perspective. | 2011 Sep 1 |
1 |
| 48 |
21666221 | Superoxide induces endothelial nitric-oxide synthase protein thiyl radical formation, a novel mechanism regulating eNOS function and coupling. | 2011 Aug 19 |
4 |
| 49 |
21724868 | Suppression of eNOS-derived superoxide by caveolin-1: a biopterin-dependent mechanism. | 2011 Sep |
2 |
| 50 |
21807618 | Acute localized administration of tetrahydrobiopterin and chronic systemic atorvastatin treatment restore cutaneous microvascular function in hypercholesterolaemic humans. | 2011 Oct 1 |
2 |