Superoxides

nitric oxide synthase 3 ; Homo sapiens







83 Article(s)
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1 35199130 [Normalization of the ratio of nitric oxide and peroxynitrite by promoting eNOS dimer activity is a new direction for diabetic nephropathy treatment]. 2022 Feb 25 1
2 32363908 Oxidative Stress, GTPCH1, and Endothelial Nitric Oxide Synthase Uncoupling in Hypertension. 2021 Mar 20 1
3 34016263 Fat-Secreted Ceramides Regulate Vascular Redox State and Influence Outcomes in Patients With Cardiovascular Disease. 2021 May 25 1
4 34356605 Endothelial Dysfunction Driven by Hypoxia-The Influence of Oxygen Deficiency on NO Bioavailability. 2021 Jul 3 1
5 34502464 Metastatic Melanoma Progression Is Associated with Endothelial Nitric Oxide Synthase Uncoupling Induced by Loss of eNOS:BH4 Stoichiometry. 2021 Sep 3 2
6 34517018 Stress activated signalling impaired protein quality control pathways in human hypertrophic cardiomyopathy. 2021 Dec 1 2
7 34638028 The evolutionary origins of peroxynitrite signalling. 2021 Nov 26 2
8 32351667 Role of the eNOS Uncoupling and the Nitric Oxide Metabolic Pathway in the Pathogenesis of Autoimmune Rheumatic Diseases. 2020 1
9 30738311 High glutathionylation of placental endothelial nitric oxide synthase in preeclampsia. 2019 Apr 6
10 26660451 Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function. 2017 Jun 1
11 25809076 The effect of different training modes on skeletal muscle microvascular density and endothelial enzymes controlling NO availability. 2016 Apr 15 3
12 27184745 The eNOS signalosome and its link to endothelial dysfunction. 2016 Jul 1
13 23836447 Humic acid induces the endothelial nitric oxide synthase phosphorylation at Ser1177 and Thr495 Via Hsp90α and Hsp90β upregulation in human umbilical vein endothelial cells. 2015 Feb 2
14 24578389 Tumour necrosis factor-alpha participates on the endothelin-1/nitric oxide imbalance in small arteries from obese patients: role of perivascular adipose tissue. 2015 Apr 1 1
15 26560496 Serine 1179 Phosphorylation of Endothelial Nitric Oxide Synthase Increases Superoxide Generation and Alters Cofactor Regulation. 2015 1
16 24405159 Reversal of SIN-1-induced eNOS dysfunction by the spin trap, DMPO, in bovine aortic endothelial cells via eNOS phosphorylation. 2014 May 4
17 24863258 Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling. 2014 Aug 1 1
18 24959009 Reactive metabolites and antioxidant gene polymorphisms in type 2 diabetes mellitus. 2014 Jan 2
19 25020117 PKC-dependent phosphorylation of eNOS at T495 regulates eNOS coupling and endothelial barrier function in response to G+ -toxins. 2014 3
20 25460725 Reactive metabolites and antioxidant gene polymorphisms in Type 2 diabetes mellitus. 2014 2
21 22996620 The effect of probiotic-fermented soy milk on enhancing the NO-mediated vascular relaxation factors. 2013 Mar 30 2
22 23395155 Uncoupling of endothelial NO synthase in atherosclerosis and vascular disease. 2013 Apr 1
23 23549379 Genetic elimination of eNOS reduces secondary complications of experimental subarachnoid hemorrhage. 2013 Jul 1
24 23781221 Arginase: the emerging therapeutic target for vascular oxidative stress and inflammation. 2013 1
25 23965989 A pivotal role for tryptophan 447 in enzymatic coupling of human endothelial nitric oxide synthase (eNOS): effects on tetrahydrobiopterin-dependent catalysis and eNOS dimerization. 2013 Oct 11 4
26 21797845 Pyridoxine inhibits endothelial NOS uncoupling induced by oxidized low-density lipoprotein via the PKCα signalling pathway in human umbilical vein endothelial cells. 2012 Feb 2
27 22167522 Tackling endothelial dysfunction by modulating NOS uncoupling: new insights into its pathogenesis and therapeutic possibilities. 2012 Mar 1 1
28 22333037 Cell oxidant stress delivery and cell dysfunction onset in type 2 diabetes. 2012 Sep 1
29 22609206 Impairment of the extrusion transporter for asymmetric dimethyl-L-arginine: a novel mechanism underlying vasospastic angina. 2012 Jun 29 2
30 21198553 Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling. 2011 Sep 1
31 21261471 S-glutathionylation reshapes our understanding of endothelial nitric oxide synthase uncoupling and nitric oxide/reactive oxygen species-mediated signaling. 2011 May 15 1
32 21642378 eNOS activation and NO function: structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity. 2011 Sep 2
33 21666221 Superoxide induces endothelial nitric-oxide synthase protein thiyl radical formation, a novel mechanism regulating eNOS function and coupling. 2011 Aug 19 10
34 21724868 Suppression of eNOS-derived superoxide by caveolin-1: a biopterin-dependent mechanism. 2011 Sep 4
35 19946124 Beta-actin association with endothelial nitric-oxide synthase modulates nitric oxide and superoxide generation from the enzyme. 2010 Feb 12 8
36 20540939 Impaired calcium influx despite hyper-reactivity in contralateral carotid following balloon injury: eNOS involvement. 2010 Sep 10 3
37 21063103 Opposite effect of Hsp90α and Hsp90β on eNOS ability to produce nitric oxide or superoxide anion in human embryonic kidney cells. 2010 1
38 21147698 [Nitric oxide and preeclampsia]. 2010 Dec 26 1
39 21179168 S-glutathionylation uncouples eNOS and regulates its cellular and vascular function. 2010 Dec 23 2
40 21188246 The role of tetrahydrobiopterin and dihydrobiopterin in ischemia/reperfusion injury when given at reperfusion. 2010 1
41 19011239 Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression. 2009 Jan 9 4
42 19176602 Effect of uncoupling endothelial nitric oxide synthase on calcium homeostasis in aged porcine endothelial cells. 2009 Apr 1 2
43 19398669 MTHFR 677 C>T Polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis. 2009 May 12 1
44 18382884 Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction. 2008 2
45 18398337 Vascular stiffness is related to superoxide generation in the vessel wall. 2008 May 1
46 18622039 Phosphorylation of endothelial nitric-oxide synthase regulates superoxide generation from the enzyme. 2008 Oct 3 1
47 18716321 Targeted increases in endothelial cell superoxide anion production stimulate eNOS-dependent nitric oxide production, not uncoupled eNOS activity. 2008 Sep 1
48 17293058 High-dose folate may improve platelet function in acute coronary syndrome and other pathologies associated with increased platelet oxidative stress. 2007 3
49 17327434 Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes. 2007 Mar 2
50 17413035 (6R)-5,6,7,8-tetrahydro-L-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm. 2007 Jun 1