6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide

sirtuin 1 ; Mus musculus







78 Article(s)
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51 29752296 Melatonin attenuates postovulatory oocyte dysfunction by regulating SIRT1 expression. 2018 Jul 1
52 30071860 Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'. 2018 Aug 2 1
53 30186119 BML-111 Reduces Neuroinflammation and Cognitive Impairment in Mice With Sepsis via the SIRT1/NF-κB Signaling Pathway. 2018 1
54 30254426 Astragaloside IV represses high glucose-induced mesangial cells activation by enhancing autophagy via SIRT1 deacetylation of NF-κB p65 subunit. 2018 1
55 27670404 Metabolic programming of a beige adipocyte phenotype by genistein. 2017 Feb 2
56 28449683 Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway. 2017 Apr 27 1
57 28493611 Fucoidan ameliorates pancreatic β-cell death and impaired insulin synthesis in streptozotocin-treated β cells and mice via a Sirt-1-dependent manner. 2017 Oct 1
58 28881659 SIRT1 inhibition promotes atherosclerosis through impaired autophagy. 2017 Aug 1 1
59 28888780 Berberine suppresses LPS-induced inflammation through modulating Sirt1/NF-κB signaling pathway in RAW264.7 cells. 2017 Nov 1
60 28952835 The SIRT1 inhibitor EX-527 suppresses mTOR activation and alleviates acute lung injury in mice with endotoxiemia. 2017 Nov 2
61 29067115 Advanced glycation end products and lipopolysaccharides stimulate interleukin-6 secretion via the RAGE/TLR4-NF-κB-ROS pathways and resveratrol attenuates these inflammatory responses in mouse macrophages. 2017 Nov 2
62 29185343 Pyrroloquinoline Quinone, a Redox-Active o-Quinone, Stimulates Mitochondrial Biogenesis by Activating the SIRT1/PGC-1α Signaling Pathway. 2017 Dec 19 1
63 27339462 α7 Nicotinic Acetylcholine Receptor Relieves Angiotensin II-Induced Senescence in Vascular Smooth Muscle Cells by Raising Nicotinamide Adenine Dinucleotide-Dependent SIRT1 Activity. 2016 Aug 1
64 27564107 SIRT1-mediated FoxOs pathways protect against apoptosis by promoting autophagy in osteoblast-like MC3T3-E1 cells exposed to sodium fluoride. 2016 Oct 4 1
65 25401748 Melatonin prevents cell death and mitochondrial dysfunction via a SIRT1-dependent mechanism during ischemic-stroke in mice. 2015 Jan 1
66 25631045 Sirtuin 1 is a negative regulator of parathyroid hormone stimulation of matrix metalloproteinase 13 expression in osteoblastic cells: role of sirtuin 1 in the action of PTH on osteoblasts. 2015 Mar 27 1
67 26299770 Selective Inhibition of SIRT2 Improves Outcomes in a Lethal Septic Model. 2015 1
68 24946089 Tissue-specific deregulation of selected HDACs characterizes ALS progression in mouse models: pharmacological characterization of SIRT1 and SIRT2 pathways. 2014 Jun 19 2
69 24959710 Spinal SIRT1 activation attenuates neuropathic pain in mice. 2014 1
70 25001863 SIRT1 inhibition during the hypoinflammatory phenotype of sepsis enhances immunity and improves outcome. 2014 Nov 2
71 25051385 Histone deacetylase III as a potential therapeutic target for the treatment of lethal sepsis. 2014 Dec 2
72 23778143 Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease. 2013 Jul 1
73 22312127 Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells. 2012 Mar 15 1
74 22447223 Sirt1 overexpression protects murine osteoblasts against TNF-α-induced injury in vitro by suppressing the NF-κB signaling pathway. 2012 May 3
75 21199917 Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival. 2011 Mar 1
76 20810901 Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity. 2010 Sep 1 1
77 20851107 Resveratrol prevents RANKL-induced osteoclast differentiation of murine osteoclast progenitor RAW 264.7 cells through inhibition of ROS production. 2010 Oct 22 1
78 18850005 Deacetylation of cortactin by SIRT1 promotes cell migration. 2009 Jan 22 1