6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide

sirtuin 1 ; Mus musculus







78 Article(s)
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1 34363008 A novel resveratrol analog upregulates sirtuin 1 and inhibits inflammatory cell infiltration in acute pancreatitis. 2022 May 2
2 34559876 Ganoderma lucidum polysaccharides protect against sepsis-induced cardiac dysfunction by activating SIRT1. 2022 Jan 5 1
3 34665857 Role of SIRT1 and Progesterone Resistance in Normal and Abnormal Endometrium. 2022 Feb 17 2
4 34738708 Resveratrol reduces DRP1-mediated mitochondrial dysfunction via the SIRT1-PGC1α signaling pathway in manganese-induced nerve damage in mice. 2022 Feb 1
5 35090502 NAD(P)H: quinone oxidoreductase 1 attenuates oxidative stress and apoptosis by regulating Sirt1 in diabetic nephropathy. 2022 Jan 28 1
6 35090883 Pterostilbene Protects the Optic Nerves and Retina in a Murine Model of Experimental Autoimmune Encephalomyelitis via Activation of SIRT1 Signaling. 2022 Apr 1 2
7 35109721 Melatonin alleviates hydrogen peroxide induced oxidative damage in MC3T3-E1 cells and promotes osteogenesis by activating SIRT1. 2022 Jan 1
8 35123833 Nicotinamide mononucleotide promotes pancreatic islet function through the SIRT1 pathway in mice after severe burns. 2022 Jan 20 1
9 35126819 Fucoxanthin Attenuates Oxidative Damage by Activating the Sirt1/Nrf2/HO-1 Signaling Pathway to Protect the Kidney from Ischemia-Reperfusion Injury. 2022 1
10 35419389 Hepatic PPARα Is Destabilized by SIRT1 Deacetylase in Undernourished Male Mice. 2022 2
11 35447391 Polydatin Improves Sepsis-Associated Encephalopathy by Activating Sirt1 and Reducing p38 Phosphorylation. 2022 Aug 1
12 35496289 SIRT1 Is Involved in the Neuroprotection of Pterostilbene Against Amyloid β 25-35-Induced Cognitive Deficits in Mice. 2022 1
13 33063734 Batroxobin inhibits astrocyte activation following nigrostriatal pathway injury. 2021 Apr 1
14 33243606 Roflupram, a novel phosphodiesterase 4 inhibitor, inhibits lipopolysaccharide-induced neuroinflammatory responses through activation of the AMPK/Sirt1 pathway. 2021 Jan 1
15 33580874 Apelin-36 Protects HT22 Cells Against Oxygen-Glucose Deprivation/Reperfusion-Induced Oxidative Stress and Mitochondrial Dysfunction by Promoting SIRT1-Mediated PINK1/Parkin-Dependent Mitophagy. 2021 Jun 1
16 33798807 Anti-inflammatory effects of curcumin in acute lung injury: In vivo and in vitro experimental model studies. 2021 Jul 1
17 33872698 Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice. 2021 Jun 1
18 34029668 Resveratrol attenuates manganese-induced oxidative stress and neuroinflammation through SIRT1 signaling in mice. 2021 Jul 2
19 34089817 Modulation of NAD+ biosynthesis activates SIRT1 and resists cisplatin-induced ototoxicity. 2021 Oct 1 1
20 34174704 Protective effect and mechanism of nicotinamide adenine dinucleotide against optic neuritis in mice with experimental autoimmune encephalomyelitis. 2021 Sep 1
21 34262905 GDF11 Alleviates Pathological Myocardial Remodeling in Diabetic Cardiomyopathy Through SIRT1-Dependent Regulation of Oxidative Stress and Apoptosis. 2021 2
22 34531546 Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson's disease models. 2021 Dec 1
23 34853445 Dapagliflozin attenuates pressure overload-induced myocardial remodeling in mice via activating SIRT1 and inhibiting endoplasmic reticulum stress. 2021 Dec 1 1
24 34970875 [Electroacupuncture postpones growth of tumors by activating SIRT1 expression to reduce inflammatory reaction and facilitate cellular autophagy in mice with transformed colorectal carcinomas]. 2021 Dec 25 1
25 31393272 SIRT1 Mediates Septic Cardiomyopathy in a Murine Model of Polymicrobial Sepsis. 2020 Jul 1
26 31877320 Role of AMPK/SIRT1-SIRT3 signaling pathway in affective disorders in unpredictable chronic mild stress mice. 2020 Mar 15 1
27 32017914 Taurine protects against cardiac dysfunction induced by pressure overload through SIRT1-p53 activation. 2020 Feb 1 1
28 32110174 Purple sweet potato color protects against hepatocyte apoptosis through Sirt1 activation in high-fat-diet-treated mice. 2020 1
29 32145722 4-Hydroxybenzaldehyde Restricts the Intracellular Growth of Toxoplasma gondii by Inducing SIRT1-Mediated Autophagy in Macrophages. 2020 Feb 1
30 32217463 SIRT1 induces the adipogenic differentiation of mouse embryonic stem cells by regulating RA-induced RAR expression via NCOR1 acetylation. 2020 Apr 1
31 32425778 Apigenin Prevents Acetaminophen-Induced Liver Injury by Activating the SIRT1 Pathway. 2020 1
32 32819566 Genetic ablation of Fas-activated serine/threonine kinase ameliorates obesity-related hepatic glucose and lipid metabolic disorders via sirtuin-1 signaling. 2020 Sep 3 2
33 33029280 Baicalin Ameliorates Cognitive Impairment and Protects Microglia from LPS-Induced Neuroinflammation via the SIRT1/HMGB1 Pathway. 2020 1
34 33034242 Loganin inhibits macrophage M1 polarization and modulates sirt1/NF-κB signaling pathway to attenuate ulcerative colitis. 2020 Dec 1
35 30456702 Sirtuin 1 inhibits TNF-α-mediated osteoclastogenesis of bone marrow-derived macrophages through both ROS generation and TRPV1 activation. 2019 May 1
36 30514750 Targeting Sirt-1 controls GVHD by inhibiting T-cell allo-response and promoting Treg stability in mice. 2019 Jan 17 1
37 30523660 Leucine regulates slow-twitch muscle fibers expression and mitochondrial function by Sirt1/AMPK signaling in porcine skeletal muscle satellite cells. 2019 Feb 1
38 30592048 The antinociceptive effect of resveratrol in bone cancer pain is inhibited by the Silent Information Regulator 1 inhibitor selisistat. 2019 May 3
39 30691004 Cannabisin F from Hemp (Cannabis sativa) Seed Suppresses Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglia as SIRT1 Modulator. 2019 Jan 25 2
40 30864731 Sirt1 promotes autophagy and inhibits apoptosis to protect cardiomyocytes from hypoxic stress. 2019 May 1
41 30917412 NAD+ supplementation rejuvenates aged gut adult stem cells. 2019 Jun 1
42 31068817 Resveratrol Promotes Diabetic Wound Healing via SIRT1-FOXO1-c-Myc Signaling Pathway-Mediated Angiogenesis. 2019 1
43 31296380 Spinal miR-34a regulates inflammatory pain by targeting SIRT1 in complete Freund's adjuvant mice. 2019 Sep 3 1
44 31430865 17β-Estradiol Modulates SIRT1 and Halts Oxidative Stress-Mediated Cognitive Impairment in a Male Aging Mouse Model. 2019 Aug 19 2
45 31450679 Melatonin Inhibits Apoptosis and Oxidative Stress of Mouse Leydig Cells via a SIRT1-Dependent Mechanism. 2019 Aug 25 1
46 31497199 Inhibition of SIRT1 promotes taste bud stem cell survival and mitigates radiation-induced oral mucositis in mice. 2019 1
47 28888894 Exercise intervention attenuates hyperhomocysteinemia-induced aortic endothelial oxidative injury by regulating SIRT1 through mitigating NADPH oxidase/LOX-1 signaling. 2018 Apr 1
48 28940469 Cytoprotective effects of xanthohumol against methylglyoxal-induced cytotoxicity in MC3T3-E1 osteoblastic cells. 2018 Feb 2
49 29331532 High-fat Diet Mediates Anxiolytic-like Behaviors in a Time-dependent Manner Through the Regulation of SIRT1 in the Brain. 2018 Feb 21 1
50 29354820 Asiatic acid suppresses neuroinflammation in BV2 microglia via modulation of the Sirt1/NF-κB signaling pathway. 2018 Feb 21 1