| 1 |
33269751 | Astaxanthin alleviates pathological brain aging through the upregulation of hippocampal synaptic proteins. | 2021 Jun |
1 |
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33889076 | Protective Effects of N1-Methylnicotinamide Against High-Fat Diet- and Age-Induced Hearing Loss via Moderate Overexpression of Sirtuin 1 Protein. | 2021 |
1 |
| 3 |
34363387 | Sirt1 and Nrf2: regulation of Leydig cell oxidant/antioxidant intracellular environment and steroid formation†. | 2021 Nov 15 |
2 |
| 4 |
31710686 | Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide. | 2020 Dec 1 |
2 |
| 5 |
31859031 | Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7. | 2020 Feb 19 |
1 |
| 6 |
32296111 | s-HBEGF/SIRT1 circuit-dictated crosstalk between vascular endothelial cells and keratinocytes mediates sorafenib-induced hand-foot skin reaction that can be reversed by nicotinamide. | 2020 Sep |
1 |
| 7 |
32987101 | Treadmill exercise mitigates neuroinflammation and increases BDNF via activation of SIRT1 signaling in a mouse model of T2DM. | 2020 Dec |
1 |
| 8 |
33068868 | Puerarin protects against myocardial ischemia/reperfusion injury by inhibiting inflammation and the NLRP3 inflammasome: The role of the SIRT1/NF-κB pathway. | 2020 Dec |
2 |
| 9 |
33072538 | (+)-Catechin & Proanthocyanidin Fraction of Uncaria gambir Roxb. Improve Adipocytes Differentiation & Glucose Uptake of 3T3-L1 Cells Via Sirtuin-1, Peroxisome Proliferator-Activated Receptor γ (PPAR γ), Glucose Transporter Type 4 (GLUT-4) Expressions. | 2020 Sep |
1 |
| 10 |
33228716 | Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice. | 2020 Nov 23 |
3 |
| 11 |
29424794 | Crocin Alleviates Myocardial Ischemia/Reperfusion-Induced Endoplasmic Reticulum Stress via Regulation of miR-34a/Sirt1/Nrf2 Pathway. | 2019 Jan |
1 |
| 12 |
30483782 | Nicotinamide induces liver regeneration and improves liver function by activating SIRT1. | 2019 Jan |
1 |
| 13 |
30836727 | Splitomicin, a SIRT1 Inhibitor, Enhances Hematopoietic Differentiation of Mouse Embryonic Stem Cells. | 2019 Mar 30 |
1 |
| 14 |
30877853 | Improved mass spectrometry-based activity assay reveals oxidative and metabolic stress as sirtuin-1 regulators. | 2019 Apr |
3 |
| 15 |
31016257 | Sir2D, a Sirtuin family protein, regulates adenylate cyclase A expression through interaction with the MybB transcription factor early in Dictyostelium development upon starvation. | 2019 Mar |
1 |
| 16 |
31020545 | Camptothecin activates SIRT1 to promote lipid catabolism through AMPK/FoxO1/ATGL pathway in C2C12 myogenic cells. | 2019 Aug |
1 |
| 17 |
31497199 | Inhibition of SIRT1 promotes taste bud stem cell survival and mitigates radiation-induced oral mucositis in mice. | 2019 |
2 |
| 18 |
28816006 | CD38 deficiency suppresses adipogenesis and lipogenesis in adipose tissues through activating Sirt1/PPARγ signaling pathway. | 2018 Jan |
1 |
| 19 |
29574225 | Dioscin alleviates non-alcoholic fatty liver disease through adjusting lipid metabolism via SIRT1/AMPK signaling pathway. | 2018 May |
1 |
| 20 |
29996125 | Activation of the Nrf2-ARE Pathway Ameliorates Hyperglycemia-Mediated Mitochondrial Dysfunction in Podocytes Partly Through Sirt1. | 2018 |
1 |
| 21 |
30318050 | Overexpression of Sirt1 in mesenchymal stem cells protects against bone loss in mice by FOXO3a deacetylation and oxidative stress inhibition. | 2018 Nov |
2 |
| 22 |
28973641 | From the Cover: l-Carnitine via PPARγ- and Sirt1-Dependent Mechanisms Attenuates Epithelial-Mesenchymal Transition and Renal Fibrosis Caused by Perfluorooctanesulfonate. | 2017 Dec 1 |
1 |
| 23 |
26924896 | Resveratrol Protects against Sepsis-Associated Encephalopathy and Inhibits the NLRP3/IL-1β Axis in Microglia. | 2016 |
1 |
| 24 |
26974211 | SIRT1, 2, 3 protect mouse oocytes from postovulatory aging. | 2016 Apr |
1 |
| 25 |
27542907 | TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy. | 2016 Nov |
1 |
| 26 |
27567590 | Long-term treatment with nicotinamide induces glucose intolerance and skeletal muscle lipotoxicity in normal chow-fed mice: compared to diet-induced obesity. | 2016 Oct |
2 |
| 27 |
27748907 | Emodin suppresses silica-induced lung fibrosis by promoting Sirt1 signaling via direct contact. | 2016 Nov |
1 |
| 28 |
27824104 | Degeneration and energy shortage in the suprachiasmatic nucleus underlies the circadian rhythm disturbance in ApoE-/- mice: implications for Alzheimer's disease. | 2016 Nov 8 |
1 |
| 29 |
24824780 | MCC inhibits beta-catenin transcriptional activity by sequestering DBC1 in the cytoplasm. | 2015 Jan 1 |
1 |
| 30 |
25727991 | Silencing Angiopoietin-Like Protein 4 (ANGPTL4) Protects Against Lipopolysaccharide-Induced Acute Lung Injury Via Regulating SIRT1 /NF-kB Pathway. | 2015 Oct |
1 |
| 31 |
25967595 | SIRT1 attenuates PAF-induced MMP-2 production via down-regulation of PAF receptor expression in vascular smooth muscle cells. | 2015 Sep |
2 |
| 32 |
24480879 | SIRT1 regulates lamellipodium extension and migration of melanoma cells. | 2014 Jun |
1 |
| 33 |
25614777 | SIRT1 functions as an important regulator of estrogen-mediated cardiomyocyte protection in angiotensin II-induced heart hypertrophy. | 2014 |
2 |
| 34 |
22934562 | Upregulation of Sirt1 in carbon-tetrachloride-induced acute liver injury. | 2013 Jul |
1 |
| 35 |
23525928 | Dynamic mobilization of PGC-1α mediates mitochondrial biogenesis for the protection of RGC-5 cells by resveratrol during serum deprivation. | 2013 Jul |
1 |
| 36 |
23735732 | Resveratrol ameliorates subacute intestinal ischemia-reperfusion injury. | 2013 Nov |
2 |
| 37 |
24246675 | Protective effects of a nicotinamide derivative, isonicotinamide, against streptozotocin-induced β-cell damage and diabetes in mice. | 2013 Dec 6 |
1 |
| 38 |
22269821 | Pancreatic ductal cells acquire mesenchymal characteristics through cell fusion with bone marrow-derived mesenchymal stem cells and SIRT1 attenuates the apoptosis of hybrid cells. | 2012 |
2 |
| 39 |
22306819 | NAD-dependent histone deacetylase, SIRT1, plays essential roles in the maintenance of hematopoietic stem cells. | 2012 Feb 24 |
1 |
| 40 |
22339667 | Insulin increases epiblast cell number of in vitro cultured mouse embryos via the PI3K/GSK3/p53 pathway. | 2012 Sep 1 |
1 |
| 41 |
22456698 | α-Lipoic acid regulates lipid metabolism through induction of sirtuin 1 (SIRT1) and activation of AMP-activated protein kinase. | 2012 Jun |
1 |
| 42 |
22992439 | Transcription levels of sirtuin family in neural stem cells and brain tissues of adult mice. | 2012 Sep 10 |
1 |
| 43 |
23096014 | Dietary zinc reduction, pyruvate supplementation, or zinc transporter 5 knockout attenuates β-cell death in nonobese diabetic mice, islets, and insulinoma cells. | 2012 Dec |
2 |
| 44 |
20736066 | Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease. | 2011 Jan |
2 |
| 45 |
21232033 | Transcriptional activation of the anchoring protein SAP97 by heat shock factor (HSF)-1 stabilizes K(v) 1.5 channels in HL-1 cells. | 2011 Apr |
1 |
| 46 |
19148549 | Chromosomal characterization and localization of the NAD+-dependent histone deacetylase gene sirtuin 1 in the mouse. | 2009 Feb |
4 |
| 47 |
19288225 | Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons. | 2009 |
1 |
| 48 |
19539713 | Nicotinamide reduces dopamine in postnatal hypothalamus and causes dopamine-deficient phenotype. | 2009 Sep 18 |
1 |
| 49 |
16917544 | The LXXLL motif of murine forkhead transcription factor FoxO1 mediates Sirt1-dependent transcriptional activity. | 2006 Sep |
3 |
| 50 |
12899610 | Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry. | 2003 Aug 12 |
6 |