| 1 |
33442914 | The interplay of ROS and the PI3K/Akt pathway in autophagy regulation. | 2022 Feb |
1 |
| 2 |
34191518 | In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to Allosterically Inhibit the Kinase Activity of mTORC1. | 2022 Jan 27 |
1 |
| 3 |
34435708 | Phosphorylation of androgen receptor by mTORC1 promotes liver steatosis and tumorigenesis. | 2022 May |
1 |
| 4 |
34636300 | Perspective on mTOR-dependent Protection in Status Epilepticus. | 2022 |
2 |
| 5 |
34757123 | Non-HLA antibodies targeting angiotensin II Type 1 receptor and endothelin-1 Type A receptors induce endothelial injury via β2-arrestin link to mTOR pathway. | 2022 Mar |
1 |
| 6 |
34779571 | Metabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR-Cas9 screen. | 2022 Jan 5 |
1 |
| 7 |
34780278 | Surfactant Protein A Enhances the Degradation of LPS-Induced TLR4 in Primary Alveolar Macrophages Involving Rab7, β-arrestin2, and mTORC1. | 2022 Feb 17 |
1 |
| 8 |
34850372 | Decreased efficacy of the ketamine and scopolamine-induced sustained antidepressant-like effects in rats receiving metformin. | 2022 Apr |
1 |
| 9 |
34852208 | RPS6 phosphorylation occurs to a greater extent in the periphery of human skeletal muscle fibers, near focal adhesions, after anabolic stimuli. | 2022 Jan 1 |
1 |
| 10 |
34861413 | GRB10 regulates β-cell mass by inhibiting β-cell proliferation and stimulating β-cell dedifferentiation. | 2022 Mar |
1 |
| 11 |
34878722 | The mTOR-lysosome axis at the centre of ageing. | 2022 Apr |
1 |
| 12 |
34905649 | Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy. | 2022 Jan |
1 |
| 13 |
34932133 | The second-generation antipsychotic drug aripiprazole modulates the serotonergic system in pancreatic islets and induces beta cell dysfunction in female mice. | 2022 Mar |
1 |
| 14 |
34968488 | Virus-mediated decrease of LKB1 activity in the mPFC diminishes stress-induced depressive-like behaviors in mice. | 2022 Mar |
1 |
| 15 |
34976315 | Yeast Crf1p: An activator in need is an activator indeed. | 2022 |
1 |
| 16 |
34977370 | Glycine represses endoplasmic reticulum stress-related apoptosis and improves intestinal barrier by activating mammalian target of rapamycin complex 1 signaling. | 2022 Mar |
1 |
| 17 |
34979914 | The functions and roles of sestrins in regulating human diseases. | 2022 Jan 3 |
1 |
| 18 |
35005610 | Hypoxia represses early responses of prostate and renal cancer cells to YM155 independent of HIF-1α and HIF-2α. | 2022 |
1 |
| 19 |
35020443 | PP2A-dependent TFEB activation is blocked by PIKfyve-induced mTORC1 activity. | 2022 Mar 1 |
1 |
| 20 |
35022234 | GATOR2 complex-mediated amino acid signaling regulates brain myelination. | 2022 Jan 18 |
1 |
| 21 |
35044284 | RAS protein activator like 2 promotes the proliferation and migration of pulmonary artery smooth muscle cell through AKT/mammalian target of Rapamycin complex 1 pathway in pulmonary hypertension. | 2022 Feb |
1 |
| 22 |
35101523 | mTORC1 inhibitor effects on rapid ketamine-induced reductions in suicidal ideation in patients with treatment-resistant depression. | 2022 Apr 15 |
1 |
| 23 |
35107743 | PI3K/Akt/mTOR pathway: a potential target for anti-SARS-CoV-2 therapy. | 2022 Jun |
1 |
| 24 |
35114453 | Isoliquiritigenin alleviates diabetic symptoms via activating AMPK and inhibiting mTORC1 signaling in diet-induced diabetic mice. | 2022 Jan 18 |
1 |
| 25 |
35125916 | AMP-activated Protein Kinase Activation Suppresses Protein Synthesis and mTORC1 Signaling in Chick Myotube Cultures. | 2022 Jan 25 |
1 |
| 26 |
35128865 | [Effects of electroacupuncture on BNDF/mTORC1 signaling pathway and synaptic plasticity in prefrontal cortex of rats exposed to chronic unpredictable mild stress]. | 2022 Jan 25 |
1 |
| 27 |
35134872 | Role of nutrient-sensing receptor GPRC6A in regulating colonic group 3 innate lymphoid cells and inflamed mucosal healing. | 2022 Feb 3 |
1 |
| 28 |
35136019 | Role of mTORC1 activity during early retinal development and lamination in human-induced pluripotent stem cell-derived retinal organoids. | 2022 Feb 8 |
1 |
| 29 |
35163619 | Cassiaside C Inhibits M1 Polarization of Macrophages by Downregulating Glycolysis. | 2022 Feb 1 |
1 |
| 30 |
35165201 | NPRL2 Inhibition of mTORC1 Controls Sodium Channel Expression and Brain Amino Acid Homeostasis. | 2022 Mar-Apr |
2 |
| 31 |
35171658 | Biomarker-Based Phase II Study of Sapanisertib (TAK-228): An mTORC1/2 Inhibitor in Patients With Refractory Metastatic Renal Cell Carcinoma. | 2022 Feb |
1 |
| 32 |
35172150 | An AMPKα2-specific phospho-switch controls lysosomal targeting for activation. | 2022 Feb 15 |
1 |
| 33 |
35181635 | ETV2 regulates PARP-1 binding protein to induce ER stress-mediated death in tuberin-deficient cells. | 2022 May |
1 |
| 34 |
35183507 | The Ragulator complex serves as a substrate-specific mTORC1 scaffold in regulating the nuclear translocation of transcription factor EB. | 2022 Mar |
1 |
| 35 |
35196486 | Loss of Slc38a4 imprinting is a major cause of mouse placenta hyperplasia in somatic cell nuclear transferred embryos at late gestation. | 2022 Feb 22 |
1 |
| 36 |
35219732 | mTOR as an eligible molecular target for possible pharmacological treatment of nonalcoholic steatohepatitis. | 2022 Apr 15 |
1 |
| 37 |
35235777 | Creatine transport and creatine kinase activity is required for CD8+ T cell immunity. | 2022 Mar 1 |
1 |
| 38 |
35238644 | Activation of Rictor/mTORC2 signaling acts as a pivotal strategy to protect against sensorineural hearing loss. | 2022 Mar 8 |
1 |
| 39 |
35240344 | Activation of Liver mTORC1 Protects Against NASH via Dual Regulation of VLDL-TAG Secretion and De Novo Lipogenesis. | 2022 |
1 |
| 40 |
35275792 | Tsc2 knockout counteracts ubiquitin-proteasome system insufficiency and delays photoreceptor loss in retinitis pigmentosa. | 2022 Mar 15 |
1 |
| 41 |
35291809 | Acute Increase of Renal Perfusion Pressure Causes Rapid Activation of mTORC1 (Mechanistic Target Of Rapamycin Complex 1) and Leukocyte Infiltration. | 2022 Jun |
1 |
| 42 |
35293604 | The Role of Zinc in Axon Formation via the mTORC1 Pathway. | 2022 May |
1 |
| 43 |
35318320 | S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions. | 2022 Mar 22 |
1 |
| 44 |
35321785 | Effects of mTORC1 inhibition on proteasome activity and levels. | 2022 Apr |
1 |
| 45 |
35321881 | IL-2 Signaling Couples the MAPK and mTORC1 Axes to Promote T Cell Proliferation and Differentiation in Teleosts. | 2022 Apr 1 |
1 |
| 46 |
35358174 | Folliculin promotes substrate-selective mTORC1 activity by activating RagC to recruit TFE3. | 2022 Mar |
1 |
| 47 |
35359988 | The mTORC1 Signaling Support Cellular Metabolism to Dictate Decidual NK Cells Function in Early Pregnancy. | 2022 |
1 |
| 48 |
35368869 | Combination of Ascorbic Acid and Menadione Induces Cytotoxic Autophagy in Human Glioblastoma Cells. | 2022 |
1 |
| 49 |
35379807 | Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function. | 2022 Apr 4 |
1 |
| 50 |
35401560 | Metabolic Reprogramming of Alloreactive T Cells Through TCR/MYC/mTORC1/E2F6 Signaling in aGvHD Patients. | 2022 |
1 |