Leucine

CREB regulated transcription coactivator 1 ; Mus musculus







133 Article(s)
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101 24762008 Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth. 2014 Jun 20 2
102 24793303 Requirement for lysosomal localization of mTOR for its activation differs between leucine and other amino acids. 2014 Sep 3
103 24806638 Leucine facilitates the insulin-stimulated glucose uptake and insulin signaling in skeletal muscle cells: involving mTORC1 and mTORC2. 2014 Aug 3
104 24847056 Cytosolic branched chain aminotransferase (BCATc) regulates mTORC1 signaling and glycolytic metabolism in CD4+ T cells. 2014 Jul 4 1
105 25231351 Suppression of mTORC1 activation in acid-α-glucosidase-deficient cells and mice is ameliorated by leucine supplementation. 2014 Nov 15 6
106 25444557 Leucine as a treatment for muscle wasting: a critical review. 2014 Dec 1
107 22898570 Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism. 2013 May 4
108 22985970 Upregulation of amino acid transporter expression induced by L-leucine availability in L6 myotubes is associated with ATF4 signaling through mTORC1-dependent mechanism. 2013 Jan 4
109 23404499 Leucine facilitates insulin signaling through a Gαi protein-dependent signaling pathway in hepatocytes. 2013 Mar 29 1
110 23525088 Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation. 2013 May 1
111 23529682 [Acne and diet]. 2013 Apr 1
112 22056783 Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo. 2012 Jan 15 1
113 22160257 Effects of leucine and citrulline versus non-essential amino acids on muscle protein synthesis in fasted rat: a common activation pathway? 2012 Sep 3
114 22258093 Reconstitution of leucine-mediated autophagy via the mTORC1-Barkor pathway in vitro. 2012 Feb 1 1
115 22424946 Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway. 2012 Apr 13 3
116 22442136 Rag GTPases and AMPK/TSC2/Rheb mediate the differential regulation of mTORC1 signaling in response to alcohol and leucine. 2012 May 15 1
117 22442749 Leucine signaling in the pathogenesis of type 2 diabetes and obesity. 2012 Mar 15 3
118 22523661 Excessive Leucine-mTORC1-Signalling of Cow Milk-Based Infant Formula: The Missing Link to Understand Early Childhood Obesity. 2012 2
119 22675606 Differential regulation of protein synthesis in skeletal muscle and liver of neonatal pigs by leucine through an mTORC1-dependent pathway. 2012 Feb 28 3
120 22749528 Glutaminolysis activates Rag-mTORC1 signaling. 2012 Aug 10 2
121 22870349 Dietary intervention in acne: Attenuation of increased mTORC1 signaling promoted by Western diet. 2012 Jan 1 2
122 21239491 Mechanisms involved in the coordinate regulation of mTORC1 by insulin and amino acids. 2011 Mar 11 1
123 21289294 ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signaling. 2011 May 1
124 21575862 Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo. 2011 May 17 1
125 22007000 Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression. 2011 Dec 15 1
126 20427710 Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway. 2010 Aug 1
127 20851890 Resveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTOR. 2010 Nov 19 1
128 18765678 Amino acid regulation of TOR complex 1. 2009 Apr 2
129 19150856 Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling. 2009 Apr 1
130 19203575 An amino acid shuffle activates mTORC1. 2009 Feb 6 1
131 17724476 Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1. 2008 Feb 14 1
132 18676370 Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling. 2008 Nov 7 1
133 18682538 Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation. 2008 Oct 1