| 51 |
29283439 | Homozygous boricua TBCK mutation causes neurodegeneration and aberrant autophagy. | 2018 Jan |
1 |
| 52 |
29422900 | Role of SLC7A5 in Metabolic Reprogramming of Human Monocyte/Macrophage Immune Responses. | 2018 |
1 |
| 53 |
29574525 | The putative leucine sensor Sestrin2 is hyperphosphorylated by acute resistance exercise but not protein ingestion in human skeletal muscle. | 2018 Jun |
1 |
| 54 |
29728917 | Short- and long-term effects of leucine and branched-chain amino acid supplementation of a protein- and energy-reduced diet on muscle protein metabolism in neonatal pigs. | 2018 Jul |
1 |
| 55 |
29784813 | Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway. | 2018 Jun 5 |
2 |
| 56 |
29844341 | Leucine/glutamine and v-ATPase/lysosomal acidification via mTORC1 activation are required for position-dependent regeneration. | 2018 May 29 |
2 |
| 57 |
30029003 | Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells. | 2018 Jul 19 |
1 |
| 58 |
30041947 | Discovery of novel leucyladenylate sulfamate surrogates as leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors. | 2018 Aug 7 |
1 |
| 59 |
30175263 | L-leucine stimulates glutamate dehydrogenase activity and glutamate synthesis by regulating mTORC1/SIRT4 pathway in pig liver. | 2018 Sep |
3 |
| 60 |
30282607 | Proteomic analyses reveal GNG12 regulates cell growth and casein synthesis by activating the Leu-mediated mTORC1 signaling pathway. | 2018 Nov |
3 |
| 61 |
27988363 | In vitro antiglioma action of indomethacin is mediated via AMP-activated protein kinase/mTOR complex 1 signalling pathway. | 2017 Feb |
2 |
| 62 |
28409828 | Leucine elicits myotube hypertrophy and enhances maximal contractile force in tissue engineered skeletal muscle in vitro. | 2017 Oct |
1 |
| 63 |
28588499 | Intake of a Ketone Ester Drink during Recovery from Exercise Promotes mTORC1 Signaling but Not Glycogen Resynthesis in Human Muscle. | 2017 |
1 |
| 64 |
28626421 | Divergent Metabolic Regulation of Autophagy and mTORC1-Early Events in Alzheimer's Disease? | 2017 |
1 |
| 65 |
28731988 | Roles of Mitogen-Activating Protein Kinase Kinase Kinase Kinase-3 (MAP4K3) in Preterm Skeletal Muscle Satellite Cell Myogenesis and Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation Regulation. | 2017 Jul 21 |
2 |
| 66 |
28882589 | Leucine-induced localization of Leucyl-tRNA synthetase in lysosome membrane. | 2017 Nov 18 |
1 |
| 67 |
28963468 | Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction. | 2017 Sep 29 |
4 |
| 68 |
29053970 | mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient. | 2017 Oct 19 |
2 |
| 69 |
29296509 | Amino acid and small GTPase regulation of mTORC1. | 2017 |
1 |
| 70 |
26449471 | Sestrin2 is a leucine sensor for the mTORC1 pathway. | 2016 Jan 1 |
6 |
| 71 |
26586190 | Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway. | 2016 Jan 1 |
3 |
| 72 |
26645537 | Leucine supplementation is anti-atrophic during paradoxical sleep deprivation in rats. | 2016 Apr |
2 |
| 73 |
26724922 | Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling. | 2016 Apr |
7 |
| 74 |
26729373 | Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndrome. | 2016 Jan 5 |
2 |
| 75 |
26836250 | Maternal diabetes promotes mTORC1 downstream signalling in rabbit preimplantation embryos. | 2016 May |
2 |
| 76 |
26884386 | Pulsatile delivery of a leucine supplement during long-term continuous enteral feeding enhances lean growth in term neonatal pigs. | 2016 Apr 15 |
2 |
| 77 |
26959180 | Toward a Molecular Definition of Leucine-Dependent mTORC1 Activation. | 2016 Mar 8 |
1 |
| 78 |
27010498 | Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation. | 2016 Aug |
6 |
| 79 |
27053525 | Activation of mTORC1 by leucine is potentiated by branched-chain amino acids and even more so by essential amino acids following resistance exercise. | 2016 Jun 1 |
2 |
| 80 |
27209231 | Discovery of (S)-4-isobutyloxazolidin-2-one as a novel leucyl-tRNA synthetase (LRS)-targeted mTORC1 inhibitor. | 2016 Jul 1 |
1 |
| 81 |
27245337 | Intake of branched-chain or essential amino acids attenuates the elevation in muscle levels of PGC-1α4 mRNA caused by resistance exercise. | 2016 Jul 1 |
1 |
| 82 |
27280402 | FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1. | 2016 |
1 |
| 83 |
27297692 | GCN2 contributes to mTORC1 inhibition by leucine deprivation through an ATF4 independent mechanism. | 2016 Jun 14 |
2 |
| 84 |
27422517 | Leucine Metabolism in T Cell Activation: mTOR Signaling and Beyond. | 2016 Jul |
1 |
| 85 |
27477288 | Leucyl-tRNA Synthetase Activates Vps34 in Amino Acid-Sensing mTORC1 Signaling. | 2016 Aug 9 |
1 |
| 86 |
27649739 | The apo-structure of the leucine sensor Sestrin2 is still elusive. | 2016 Sep 20 |
5 |
| 87 |
27690010 | Recent Advances in Understanding Amino Acid Sensing Mechanisms that Regulate mTORC1. | 2016 Sep 29 |
1 |
| 88 |
27933890 | Discovery of Leucyladenylate Sulfamates as Novel Leucyl-tRNA Synthetase (LRS)-Targeted Mammalian Target of Rapamycin Complex 1 (mTORC1) Inhibitors. | 2016 Nov 23 |
1 |
| 89 |
27934653 | Leucine and Mammalian Target of Rapamycin-Dependent Activation of Muscle Protein Synthesis in Aging. | 2016 Dec |
1 |
| 90 |
25567907 | Metabolism. Differential regulation of mTORC1 by leucine and glutamine. | 2015 Jan 9 |
1 |
| 91 |
25774780 | High-fat feeding impairs nutrient sensing and gut brain integration in the caudomedial nucleus of the solitary tract in mice. | 2015 |
1 |
| 92 |
25872869 | The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. | 2015 Apr 14 |
2 |
| 93 |
25998567 | LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation. | 2015 May 22 |
2 |
| 94 |
26007333 | Leucine Promotes Proliferation and Differentiation of Primary Preterm Rat Satellite Cells in Part through mTORC1 Signaling Pathway. | 2015 May 8 |
1 |
| 95 |
26169935 | Leucine does not affect mechanistic target of rapamycin complex 1 assembly but is required for maximal ribosomal protein s6 kinase 1 activity in human skeletal muscle following resistance exercise. | 2015 Oct |
2 |
| 96 |
27021048 | [Role of the mTOR pathway in the central regulation of energy balance]. | 2015 |
1 |
| 97 |
24284439 | Role of amino acid transporters in amino acid sensing. | 2014 Jan |
1 |
| 98 |
24476474 | Absence of leucine in an essential amino acid supplement reduces activation of mTORC1 signalling following resistance exercise in young females. | 2014 Feb |
3 |
| 99 |
24722568 | Leucyl-tRNA synthetase regulates lactation and cell proliferation via mTOR signaling in dairy cow mammary epithelial cells. | 2014 Apr 9 |
1 |
| 100 |
24740400 | Ursolic acid inhibits leucine-stimulated mTORC1 signaling by suppressing mTOR localization to lysosome. | 2014 |
2 |