| 1 |
34735991 | Validation of a rapid liquid chromatography tandem mass spectrometric method for the quantitative analysis of vistusertib. | 2022 Jan 20 |
1 |
| 2 |
35551299 | Safety and Efficacy of the mTOR Inhibitor, Vistusertib, Combined With Anastrozole in Patients With Hormone Receptor-Positive Recurrent or Metastatic Endometrial Cancer: The VICTORIA Multicenter, Open-label, Phase 1/2 Randomized Clinical Trial. | 2022 May 12 |
1 |
| 3 |
35595819 | Aberrant cholesterol metabolic signaling impairs antitumor immunosurveillance through natural killer T cell dysfunction in obese liver. | 2022 May 20 |
2 |
| 4 |
33471836 | PI3k inhibitors (BKM120 and BYL719) as radiosensitizers for head and neck squamous cell carcinoma during radiotherapy. | 2021 |
1 |
| 5 |
34560229 | Dual mTORC1/2 inhibitor AZD2014 diminishes myeloid-derived suppressor cells accumulation in ovarian cancer and delays tumor growth. | 2021 Dec 28 |
1 |
| 6 |
34674743 | AZD2014, a dual mTOR inhibitor, attenuates cardiac hypertrophy in vitro and in vivo. | 2021 Oct 21 |
2 |
| 7 |
31769520 | Therapeutic Enhancement of Verteporfin-mediated Photodynamic Therapy by mTOR Inhibitors. | 2020 Mar |
1 |
| 8 |
32111983 | Enhanced autocrine FGF19/FGFR4 signaling drives the progression of lung squamous cell carcinoma, which responds to mTOR inhibitor AZD2104. | 2020 Apr |
1 |
| 9 |
32325639 | Synergistic Effects of Combination Therapy with AKT and mTOR Inhibitors on Bladder Cancer Cells. | 2020 Apr 18 |
1 |
| 10 |
32591533 | Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons. | 2020 Jun 26 |
1 |
| 11 |
32595135 | Noninvasive MRI Native T1 Mapping Detects Response to MYCN-targeted Therapies in the Th-MYCN Model of Neuroblastoma. | 2020 Aug 15 |
2 |
| 12 |
32737414 | Synergistic drug combinations and machine learning for drug repurposing in chordoma. | 2020 Jul 31 |
1 |
| 13 |
33142217 | Directly imaging the localisation and photosensitization properties of the pan-mTOR inhibitor, AZD2014, in living cancer cells. | 2020 Dec |
2 |
| 14 |
31100427 | Investigation of the novel mTOR inhibitor AZD2014 in neuronal ischemia. | 2019 Jul 27 |
3 |
| 15 |
31298338 | Combined mTOR/MEK inhibition prevents proliferation and induces apoptosis in NF2-mutant tumors. | 2019 Jul |
1 |
| 16 |
29389967 | RAPTOR up-regulation contributes to resistance of renal cancer cells to PI3K-mTOR inhibition. | 2018 |
1 |
| 17 |
29709474 | Keratinocyte growth factor protects endometrial cells from oxygen glucose deprivation/re-oxygenation via activating Nrf2 signaling. | 2018 Jun 18 |
1 |
| 18 |
30097489 | Combined Inhibition of PI3Kβ and mTOR Inhibits Growth of PTEN-null Tumors. | 2018 Nov |
1 |
| 19 |
27863413 | RICTOR amplification identifies a subgroup in small cell lung cancer and predicts response to drugs targeting mTOR. | 2017 Jan 24 |
1 |
| 20 |
28388555 | Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-1. | 2017 May 23 |
1 |
| 21 |
27031247 | AZD2014 Radiosensitizes Oral Squamous Cell Carcinoma by Inhibiting AKT/mTOR Axis and Inducing G1/G2/M Cell Cycle Arrest. | 2016 |
1 |
| 22 |
27267837 | BEZ235 (PIK3/mTOR inhibitor) Overcomes Pazopanib Resistance in Patient-Derived Refractory Soft Tissue Sarcoma Cells. | 2016 Jun |
1 |
| 23 |
27311860 | mTOR inhibition sensitizes human hepatocellular carcinoma cells to resminostat. | 2016 Sep 2 |
1 |
| 24 |
25628925 | Dramatic antitumor effects of the dual mTORC1 and mTORC2 inhibitor AZD2014 in hepatocellular carcinoma. | 2015 |
1 |
| 25 |
26148118 | Potentiation of Growth Inhibitory Responses of the mTOR Inhibitor Everolimus by Dual mTORC1/2 Inhibitors in Cultured Breast Cancer Cell Lines. | 2015 |
1 |
| 26 |
26358751 | AZD2014, an Inhibitor of mTORC1 and mTORC2, Is Highly Effective in ER+ Breast Cancer When Administered Using Intermittent or Continuous Schedules. | 2015 Nov |
1 |
| 27 |
26359452 | Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC. | 2015 Oct 15 |
1 |
| 28 |
26473447 | The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression. | 2015 Nov 10 |
2 |
| 29 |
24970801 | Synergistic induction of apoptosis by combination of BTK and dual mTORC1/2 inhibitors in diffuse large B cell lymphoma. | 2014 Jul 15 |
1 |
| 30 |
25193511 | MEDI-573, alone or in combination with mammalian target of rapamycin inhibitors, targets the insulin-like growth factor pathway in sarcomas. | 2014 Nov |
2 |