bufalin

mechanistic target of rapamycin kinase ; Homo sapiens







16 Article(s)
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1 32905663 Bufalin inhibits ovarian carcinoma via targeting mTOR/HIF-α pathway. 2021 Feb 3
2 33530915 Effect of PI3K/AKT/mTOR Signaling Pathway on Regulating and Controlling the Anti-Invasion and Metastasis of Hepatoma Cells by Bufalin. 2021 2
3 34512368 Targeting Autophagy with Natural Compounds in Cancer: A Renewed Perspective from Molecular Mechanisms to Targeted Therapy. 2021 1
4 30468278 Bufalin induces protective autophagy by Cbl-b regulating mTOR and ERK signaling pathways in gastric cancer cells. 2019 Jan 3
5 29620259 Synergistic anti-hepatoma effect of bufalin combined with sorafenib via mediating the tumor vascular microenvironment by targeting mTOR/VEGF signaling. 2018 Jun 2
6 29805658 Bufalin induces apoptosis in human esophageal carcinoma ECA109 cells by inhibiting the activation of the mTOR/p70S6K pathway. 2018 Jun 5
7 30128000 Bufalin suppresses the proliferation and metastasis of renal cell carcinoma by inhibiting the PI3K/Akt/mTOR signaling pathway. 2018 Sep 4
8 28492559 MK2206 enhances the cytocidal effects of bufalin in multiple myeloma by inhibiting the AKT/mTOR pathway. 2017 May 11 3
9 28656204 Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice. 2017 Aug 2
10 26958938 Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway. 2016 Apr 12 2
11 27357249 Bufalin reverses intrinsic and acquired drug resistance to cisplatin through the AKT signaling pathway in gastric cancer cells. 2016 Aug 1
12 24550689 Bufalin induces the interplay between apoptosis and autophagy in glioma cells through endoplasmic reticulum stress. 2014 1
13 23344047 Anticancer effects of bufalin on human hepatocellular carcinoma HepG2 cells: roles of apoptosis and autophagy. 2013 Jan 11 1
14 23799775 Discovery of bufadienolides as a novel class of ClC-3 chloride channel activators with antitumor activities. 2013 Jul 25 1
15 24325059 [Effect of bufalin combined gefitinib on lung cancer H1975 cells and its mechanisms research]. 2013 Aug 1
16 22858649 Bufalin increases sensitivity to AKT/mTOR-induced autophagic cell death in SK-HEP-1 human hepatocellular carcinoma cells. 2012 Oct 1