| 1 |
34724274 | Targeting lactate metabolism and glycolytic pathways in the tumor microenvironment by natural products: A promising strategy in combating cancer. | 2022 Mar |
1 |
| 2 |
34973450 | Upregulated hexokinase 2 expression induces the apoptosis of dopaminergic neurons by promoting lactate production in Parkinson's disease. | 2022 Feb |
2 |
| 3 |
35069879 | CRNDE silencing promotes apoptosis and enhances cisplatin sensitivity of colorectal carcinoma cells by inhibiting the Akt/mTORC1-mediated Warburg effect. | 2022 Feb |
1 |
| 4 |
35589065 | Lactate inhibits osteogenic differentiation of human periodontal ligament stem cells via autophagy through the MCT1-mTOR signaling pathway. | 2022 May 16 |
2 |
| 5 |
32878490 | Holothuria scabra Extract Induces Cell Apoptosis and Suppresses Warburg Effect by Down-Regulating Akt/mTOR/HIF-1 Axis in MDA-MB-231 Breast Cancer Cells. | 2021 |
1 |
| 6 |
34656878 | Lactate in the tumour microenvironment: From immune modulation to therapy. | 2021 Nov |
2 |
| 7 |
34746839 | Effect of lactate administration on mouse skeletal muscle under calorie restriction. | 2021 |
2 |
| 8 |
32698682 | Acute effects of lactic acid-fermented and enzyme-digested soybean on protein synthesis via mTOR signaling in the skeletal muscle. | 2020 Nov |
1 |
| 9 |
32917658 | Lactate-Modulated Immunosuppression of Myeloid-Derived Suppressor Cells Contributes to the Radioresistance of Pancreatic Cancer. | 2020 Nov |
2 |
| 10 |
32985258 | The effects and mechanisms of isoliquiritigenin loaded nanoliposomes regulated AMPK/mTOR mediated glycolysis in colorectal cancer. | 2020 Dec |
1 |
| 11 |
33013932 | Regulation of RLR-Mediated Antiviral Responses of Human Dendritic Cells by mTOR. | 2020 |
1 |
| 12 |
30670777 | Effect of PTEN inactivating germline mutations on innate immune cell function and thyroid cancer-induced macrophages in patients with PTEN hamartoma tumor syndrome. | 2019 May |
1 |
| 13 |
30867812 | Tumor-secreted dickkopf2 accelerates aerobic glycolysis and promotes angiogenesis in colorectal cancer. | 2019 |
1 |
| 14 |
30871777 | Fubp1 supports the lactate-Akt-mTOR axis through the upregulation of Hk1 and Hk2. | 2019 Apr 23 |
2 |
| 15 |
30881132 | Construction of a GLUT-1 and HIF-1α gene knockout cell model in HEp-2 cells using the CRISPR/Cas9 technique. | 2019 |
1 |
| 16 |
31496162 | [High dose vitamin C inhibits proliferation of breast cancer cells through reducing glycolysis and protein synthesis]. | 2019 May 25 |
1 |
| 17 |
31798707 | Macrophage transcriptome modification induced by hypoxia and lactate. | 2019 Dec |
1 |
| 18 |
29886375 | Down-regulation of miR-214 inhibits proliferation and glycolysis in non-small-cell lung cancer cells via down-regulating the expression of hexokinase 2 and pyruvate kinase isozyme M2. | 2018 Sep |
1 |
| 19 |
29916308 | The mTOR Pathway Regulates PKM2 to Affect Glycolysis in Esophageal Squamous Cell Carcinoma. | 2018 Jan 1 |
1 |
| 20 |
28578659 | Rapamycin (mTORC1 inhibitor) reduces the production of lactate and 2-hydroxyglutarate oncometabolites in IDH1 mutant fibrosarcoma cells. | 2017 Jun 2 |
1 |
| 21 |
28624789 | Pediatric and adult glioblastoma radiosensitization induced by PI3K/mTOR inhibition causes early metabolic alterations detected by nuclear magnetic resonance spectroscopy. | 2017 Jul 18 |
1 |
| 22 |
28704425 | In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells. | 2017 |
1 |
| 23 |
28731193 | Promotion of glycolysis by HOTAIR through GLUT1 upregulation via mTOR signaling. | 2017 Sep |
2 |
| 24 |
27050525 | ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer. | 2016 Apr 12 |
1 |
| 25 |
27379200 | (13)C MRS and LC-MS Flux Analysis of Tumor Intermediary Metabolism. | 2016 |
2 |
| 26 |
27995420 | Lactic acid in tumor microenvironments causes dysfunction of NKT cells by interfering with mTOR signaling. | 2016 Dec |
1 |
| 27 |
28123869 | Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages. | 2016 |
1 |
| 28 |
25266796 | A lentiviral sponge for miRNA-21 diminishes aerobic glycolysis in bladder cancer T24 cells via the PTEN/PI3K/AKT/mTOR axis. | 2015 Jan |
1 |
| 29 |
25484022 | Lactate promotes resistance to glucose starvation via upregulation of Bcl-2 mediated by mTOR activation. | 2015 Feb |
2 |
| 30 |
25807077 | Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effect. | 2015 |
1 |
| 31 |
26158266 | Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer Cells. | 2015 |
1 |
| 32 |
26251974 | Cyclic mechanical stretch promotes energy metabolism in osteoblast-like cells through an mTOR signaling-associated mechanism. | 2015 Oct |
1 |
| 33 |
24496328 | M(o)TOR of pseudo-hypoxic state in aging: rapamycin to the rescue. | 2014 |
1 |
| 34 |
22711601 | Decreased lactate concentration and glycolytic enzyme expression reflect inhibition of mTOR signal transduction pathway in B-cell lymphoma. | 2013 Jan |
4 |
| 35 |
22156546 | Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma. | 2012 Mar |
2 |
| 36 |
23181020 | Computational modeling of the metabolic States regulated by the kinase akt. | 2012 |
1 |
| 37 |
22156391 | Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression. | 2011 Nov |
1 |