Dichloroacetic Acid

mechanistic target of rapamycin kinase ; Homo sapiens







12 Article(s)
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1 34678088 PDGFRβ modulates aerobic glycolysis in osteosarcoma HOS cells via the PI3K/AKT/mTOR/c-Myc pathway. 2022 Feb 1
2 34576192 Metformin and Dichloroacetate Suppress Proliferation of Liver Cancer Cells by Inhibiting mTOR Complex 1. 2021 Sep 17 1
3 31919406 MiR-107 confers chemoresistance to colorectal cancer by targeting calcium-binding protein 39. 2020 Mar 1
4 31762813 Dichloroacetate Overcomes Oxaliplatin Chemoresistance in Colorectal Cancer through the miR-543/PTEN/Akt/mTOR Pathway. 2019 2
5 29844702 Dichloroacetate enhances the antitumor efficacy of chemotherapeutic agents via inhibiting autophagy in non-small-cell lung cancer. 2018 1
6 30513596 Propranolol Promotes Glucose Dependence and Synergizes with Dichloroacetate for Anti-Cancer Activity in HNSCC. 2018 Nov 30 2
7 28928817 Dichloroacetate induces protective autophagy in esophageal squamous carcinoma cells. 2017 Sep 1
8 25976231 Overexpression of pyruvate dehydrogenase kinase supports dichloroacetate as a candidate for cutaneous melanoma therapy. 2015 Jun 1
9 25995437 The PI3K/Akt Pathway Regulates Oxygen Metabolism via Pyruvate Dehydrogenase (PDH)-E1α Phosphorylation. 2015 Aug 2
10 24892448 Dichloroacetate induces autophagy in colorectal cancer cells and tumours. 2014 Jul 15 1
11 24201812 Dichloroacetate induces protective autophagy in LoVo cells: involvement of cathepsin D/thioredoxin-like protein 1 and Akt-mTOR-mediated signaling. 2013 Nov 7 3
12 11259315 Direct imaging of dehydrogenase activity within living cells using enzyme-dependent fluorescence recovery after photobleaching (ED-FRAP). 2001 Apr 1