| 1 |
33880473 | Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2. | 2022 Apr 6 |
3 |
| 2 |
34180556 | Xanthatin inhibits human colon cancer cells progression via mTOR signaling mediated energy metabolism alteration. | 2022 Feb |
1 |
| 3 |
34191518 | In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to Allosterically Inhibit the Kinase Activity of mTORC1. | 2022 Jan 27 |
1 |
| 4 |
34304300 | Sirolimus in infants with congenital hyperinsulinism (CHI) - a single-centre experience. | 2022 Jan |
4 |
| 5 |
34331820 | Rapamycin promotes autophagy cell death of Kaposi's sarcoma cells through P75NTR activation. | 2022 Feb |
2 |
| 6 |
34368895 | MiR-107 inhibits the sprouting of intersegmental vessels of zebrafish embryos. | 2022 May |
1 |
| 7 |
34619135 | Chronic Exposure to Palmitic Acid Down-Regulates AKT in Beta-Cells through Activation of mTOR. | 2022 Jan |
1 |
| 8 |
34662660 | Activated Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin Signal and Suppressed Autophagy Participate in Protection Offered by Licochalcone A Against Amyloid-β Peptide Fragment 25-35-Induced Injury in SH-SY5Y Cells. | 2022 Jan |
1 |
| 9 |
34739690 | Hormetic effect of low doses of rapamycin triggers anti-aging cascades in WRL-68 cells by modulating an mTOR-mitochondria cross-talk. | 2022 Jan |
5 |
| 10 |
34748756 | Neuronal Glypican4 promotes mossy fiber sprouting through the mTOR pathway after pilocarpine-induced status epilepticus in mice. | 2022 Jan |
3 |
| 11 |
34757123 | Non-HLA antibodies targeting angiotensin II Type 1 receptor and endothelin-1 Type A receptors induce endothelial injury via β2-arrestin link to mTOR pathway. | 2022 Mar |
1 |
| 12 |
34797524 | ERK inhibition in glioblastoma is associated with autophagy activation and tumorigenesis suppression. | 2022 Jan |
1 |
| 13 |
34839054 | A phase II study of sequential decitabine and rapamycin in acute myelogenous leukemia. | 2022 Jan |
2 |
| 14 |
34847519 | In silico development of new PET radiopharmaceuticals from mTOR inhibitors. | 2022 Mar |
2 |
| 15 |
34874016 | mTOR inhibitor improves testosterone-induced myocardial hypertrophy in hypertensive rats. | 2022 Jan 31 |
1 |
| 16 |
34902358 | Maf1 regulates axonal regeneration of retinal ganglion cells after injury. | 2022 Feb |
1 |
| 17 |
34904422 | Capsid protein from red-spotted grouper nervous necrosis virus induces incomplete autophagy by inactivating the HSP90ab1-AKT-MTOR pathway. | 2022 Jan 18 |
1 |
| 18 |
34919773 | Sirolimus or Everolimus Improves Survival After Liver Transplantation for Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis. | 2022 Jun |
2 |
| 19 |
34936813 | Mammalian Target of Rapamycin Inhibitor Rapamycin Alleviates 7-Ketocholesterol Induced Inflammatory Responses and Vascular Endothelial Growth Factor Elevation by Regulating MAPK Pathway in Human Retinal Pigment Epithelium Cells. | 2022 Mar |
3 |
| 20 |
34959190 | Alpha-crystallin B chains in trastuzumab-resistant breast cancer cells promote endothelial cell tube formation through activating mTOR. | 2022 Jan 15 |
1 |
| 21 |
34961940 | Glutamine promotes the generation of B10+ cells via the mTOR/GSK3 pathway. | 2022 Mar |
1 |
| 22 |
34965300 | A Combination therapy using an mTOR inhibitor and Honokiol effectively induces autophagy through the modulation of AXL and Rubicon in renal cancer cells and restricts renal tumor growth following organ transplantation. | 2022 May 19 |
2 |
| 23 |
34983907 | Mammalian Target of Rapamycin as the Therapeutic Target of Vascular Proliferative Diseases: Past, Present, and Future. | 2022 Apr 1 |
2 |
| 24 |
34987640 | Tumor-infiltrating lymphocytes are functionally inactivated by CD90+ stromal cells and reactivated by combined Ibrutinib and Rapamycin in human pleural mesothelioma. | 2022 |
1 |
| 25 |
35007565 | Preclinical efficacy and involvement of mTOR signaling in the mechanism of Orf virus against nasopharyngeal carcinoma cells. | 2022 Feb 15 |
1 |
| 26 |
35012940 | Functional impact and targetability of PI3KCA, GNAS, and PTEN mutations in a spindle cell rhabdomyosarcoma with MYOD1 L122R mutation. | 2022 Jan |
1 |
| 27 |
35040506 | mTOR Inhibition with Sirolimus in Multiple System Atrophy: A Randomized, Double-Blind, Placebo-Controlled Futility Trial and 1-Year Biomarker Longitudinal Analysis. | 2022 Apr |
3 |
| 28 |
35040598 | Sirolimus for epileptic seizures associated with focal cortical dysplasia type II. | 2022 Feb |
2 |
| 29 |
35051778 | Mesenchyme homeobox 2 has a cancer-inhibiting function in breast carcinoma via affection of the PI3K/AKT/mTOR and ERK1/2 pathways. | 2022 Feb 19 |
1 |
| 30 |
35059731 | Possible effects of sirolimus treatment on the long‑term efficacy of COVID‑19 vaccination in patients with β‑thalassemia: A theoretical perspective. | 2022 Mar |
1 |
| 31 |
35085453 | Rapamycin Treatment Is Beneficial for the Generation of Rabbit-Induced Pluripotent Stem-Like Cells. | 2022 Feb |
2 |
| 32 |
35087713 | Brain targeted delivery of rapamycin using transferrin decorated nanostructured lipid carriers. | 2022 |
2 |
| 33 |
35088890 | Antitumor activity of the dual PI3K/mTOR inhibitor gedatolisib and the involvement of ABCB1 in gedatolisib resistance in canine tumor cells. | 2022 Apr |
1 |
| 34 |
35107743 | PI3K/Akt/mTOR pathway: a potential target for anti-SARS-CoV-2 therapy. | 2022 Jun |
1 |
| 35 |
35114332 | Rapamycin ameliorates age-related hearing loss in C57BL/6J mice by enhancing autophagy in the SGNs. | 2022 Feb 16 |
1 |
| 36 |
35125022 | Efficacy of mTOR inhibitors (sirolimus) in isolated limb overgrowth: a systematic review. | 2022 Jul |
1 |
| 37 |
35143341 | Rap_GAP Domain of TSC2 Contributes to Tumor Suppression Through mTOR Signaling in Human Hepatocellular Carcinoma. | 2022 Feb |
1 |
| 38 |
35143831 | Branched chain amino acids are associated with metabolic complications in liver transplant recipients. | 2022 Apr |
1 |
| 39 |
35149934 | Rapamycin attenuated podocyte apoptosis via upregulation of nestin in Ang II-induced podocyte injury. | 2022 Mar |
3 |
| 40 |
35153184 | Expression profile of the PI3K-AKT-mTOR pathway in head and neck squamous cell carcinoma: Data from Brazilian population. | 2022 Apr |
1 |
| 41 |
35159256 | PROX1, a Key Mediator of the Anti-Proliferative Effect of Rapamycin on Hepatocellular Carcinoma Cells. | 2022 Jan 27 |
1 |
| 42 |
35163076 | Modulating mTOR Signaling as a Promising Therapeutic Strategy for Atherosclerosis. | 2022 Jan 21 |
1 |
| 43 |
35176419 | p70 S6 kinase as a therapeutic target in cancers: More than just an mTOR effector. | 2022 Jun 1 |
1 |
| 44 |
35182368 | Development of a novel rapamycin loaded nano- into micro-formulation for treatment of lung inflammation. | 2022 Feb 19 |
2 |
| 45 |
35183509 | PI3K/mTOR inhibition prevents anal cancer in mice with established low-grade anal dysplasia. | 2022 Apr |
1 |
| 46 |
35184679 | Rapamycin ameliorates chronic intermittent hypoxia and sleep deprivation-induced renal damage via the mammalian target of rapamycin (mTOR)/NOD-like receptor protein 3 (NLRP3) signaling pathway. | 2022 Mar |
4 |
| 47 |
35192892 | MARK2/4 promotes Warburg effect and cell growth in non-small cell lung carcinoma through the AMPKα1/mTOR/HIF-1α signaling pathway. | 2022 Jul |
1 |
| 48 |
35218870 | mTOR signaling as a molecular target for the alleviation of Alzheimer's disease pathogenesis. | 2022 May |
1 |
| 49 |
35235808 | Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin. | 2022 Mar 1 |
1 |
| 50 |
35246210 | Perfect match: mTOR inhibitors and tuberous sclerosis complex. | 2022 Mar 4 |
1 |