Tacrolimus

mechanistic target of rapamycin kinase ; Homo sapiens







35 Article(s)
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1 34793770 The mTOR inhibitor everolimus attenuates tacrolimus-induced renal interstitial fibrosis in rats. 2022 Jan 1 2
2 32541562 Thirty Years of Tacrolimus in Clinical Practice. 2021 Mar 1 1
3 33431785 Suppression of Allograft Fibrosis by Regulation of Mammalian Target of Rapamycin-Related Protein Expression in Kidney-Transplanted Recipients Treated with Everolimus and Reduced Tacrolimus. 2021 Jan 12 1
4 33830489 Tacrolimus, Sirolimus and Everolimus Doses in HIV-Infected Solid-Organ Recipients, Requiring a Cobicistat-Based Antiretroviral Regimen: Report of Three Cases and Review. 2021 Jun 1
5 34046945 Efficacy and safety of mammalian target of rapamycin inhibitors following intestinal and multivisceral transplantation. 2021 Jul 1
6 34847842 Can We Use mTOR Inhibitors for COVID-19 Therapy? 2021 Nov 30 1
7 31413313 A monocentric study of steroid-refractory acute graft-versus-host disease treatment with tacrolimus and mTOR inhibitor. 2020 Jan 1
8 32006551 Characterization of three FK506-binding proteins in the entomopathogenic fungus Beauveria bassiana. 2020 Mar 3
9 32732848 Use of De Novo mTOR Inhibitors in Hypersensitized Kidney Transplant Recipients: Experience From Clinical Practice. 2020 Aug 1
10 32956634 Tacrolimus, a rapamycin target protein inhibitor, exerts anti-cystic echinococcosis effects both in vitro and in vivo. 2020 Dec 2
11 33145270 Differential expression of genes related to calcineurin and mTOR signaling and regulatory miRNAs in peripheral blood from kidney recipients under tacrolimus-based therapy. 2020 Sep 3
12 30532015 Rapamycin-inspired macrocycles with new target specificity. 2019 Mar 1
13 31271885 Effect of Sirolimus on Immune Reconstitution Following Myeloablative Allogeneic Stem Cell Transplantation: An Ancillary Analysis of a Randomized Controlled Trial Comparing Tacrolimus/Sirolimus and Tacrolimus/Methotrexate (Blood and Marrow Transplant Clinical Trials Network/BMT CTN 0402). 2019 Nov 1
14 31385180 Outcomes of sirolimus regimens in 65-year-old and older kidney transplant recipients: a registry-based observational study. 2019 Nov 1
15 31447189 Preventive Role of mTOR Inhibitor in Post-Kidney Transplant Urothelial Carcinoma. 2019 Oct 2
16 29676018 Conversion from tacrolimus-mycophenolate mofetil to tacrolimus-mTOR immunosuppression after kidney-pancreas transplantation reduces the incidence of both BK and CMV viremia. 2018 Jun 4
17 29757021 Advagraf® with or without an induction therapy for de novo kidney-transplant recipients. 2018 Jun 1
18 28633129 Inhibition effect of tacrolimus and platelet-derived growth factor-BB on restenosis after vascular intimal injury. 2017 Sep 1
19 26613512 Effects of mTOR and calcineurin inhibitors combined therapy in Epstein-Barr virus positive and negative Burkitt lymphoma cells. 2016 Jan 1
20 24861504 Focus on mTOR inhibitors and tacrolimus in renal transplantation: pharmacokinetics, exposure-response relationships, and clinical outcomes. 2014 Jun 1
21 25491391 Autologous bone marrow derived mesenchymal stromal cell therapy in combination with everolimus to preserve renal structure and function in renal transplant recipients. 2014 Dec 10 1
22 22875481 Inhibition of calcineurin in the prefrontal cortex induced depressive-like behavior through mTOR signaling pathway. 2013 Jan 2
23 23577651 Long-term mTOR inhibitors administration evokes altered calcium homeostasis and platelet dysfunction in kidney transplant patients. 2013 May 1
24 23696253 Everolimus: a guide to its use in liver transplantation. 2013 Aug 1
25 23839048 FKBPs and the Akt/mTOR pathway. 2013 Aug 1 1
26 20304212 Rescue immunosuppression with mammalian target of rapamycin inhibitor drugs in liver transplantation. 2010 Mar 2
27 21182472 FK506 binding proteins as targets in anticancer therapy. 2010 Nov 1 1
28 19715866 Efficacy, tolerance, and safety of mammalian target of rapamycin inhibitors as rescue immunosuppressants in liver transplantation. 2009 Jul-Aug 2
29 19081378 Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. 2008 Dec 10 2
30 17038582 Impairment of T cell interactions with antigen-presenting cells by immunosuppressive drugs reveals involvement of calcineurin and NF-kappaB in immunological synapse formation. 2007 Jan 1
31 17645716 Comparison of sirolimus and everolimus in their effects on blood lipid profiles and haematological parameters in heart transplant recipients. 2007 Jul-Aug 2
32 17175265 Genomic profiling of kidney ischemia-reperfusion reveals expression of specific alloimmunity-associated genes: Linking "immune" and "nonimmune" injury events. 2006 Dec 1
33 12740386 Mechanism of ribosomal p70S6 kinase activation by granulocyte macrophage colony-stimulating factor in neutrophils: cooperation of a MEK-related, THR421/SER424 kinase and a rapamycin-sensitive, m-TOR-related THR389 kinase. 2003 Jul 25 2
34 11792863 Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin. 2002 Jan 22 1
35 10775131 Fluid flow activates a regulator of translation, p70/p85 S6 kinase, in human endothelial cells. 2000 May 2