Trehalose

mechanistic target of rapamycin kinase ; Homo sapiens







18 Article(s)
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1 35199998 Carrier-Free Trehalose-Based Nanomotors Targeting Macrophages in Inflammatory Plaque for Treatment of Atherosclerosis. 2022 Mar 22 1
2 35348612 Exploring the mechanism of trehalose: dual functions of PI3K/Akt and VPS34/mTOR pathways in porcine oocytes and cumulus cells†. 2022 Mar 25 3
3 35455952 Lysosomes Dysfunction Causes Mitophagy Impairment in PBMCs of Sporadic ALS Patients. 2022 Apr 9 2
4 32554696 Trehalose Inhibits Human Immunodeficiency Virus Type 1 Infection in Primary Human Macrophages and CD4+ T Lymphocytes through Two Distinct Mechanisms. 2020 Aug 17 3
5 31013754 Trehalose Modulates Autophagy Process to Counteract Gliadin Cytotoxicity in an In Vitro Celiac Disease Model. 2019 Apr 12 2
6 31481932 Autophagic and Proteasomal Mediated Removal of Mutant Androgen Receptor in Muscle Models of Spinal and Bulbar Muscular Atrophy. 2019 1
7 29241092 Trehalose protects against oxidative stress by regulating the Keap1-Nrf2 and autophagy pathways. 2018 May 1
8 30166521 Dual role of autophagy on docetaxel-sensitivity in prostate cancer cells. 2018 Aug 30 1
9 28981117 Trehalose ameliorates oxidative stress-mediated mitochondrial dysfunction and ER stress via selective autophagy stimulation and autophagic flux restoration in osteoarthritis development. 2017 Oct 5 1
10 26295831 Novel Lactulose and Melibiose Targeting Autophagy to Reduce PolyQ Aggregation in Cell Models of Spinocerebellar Ataxia 3. 2016 1
11 26559848 Trehalose, an mTOR-Independent Inducer of Autophagy, Inhibits Human Cytomegalovirus Infection in Multiple Cell Types. 2016 Feb 1 2
12 27328819 Trehalose, sucrose and raffinose are novel activators of autophagy in human keratinocytes through an mTOR-independent pathway. 2016 Jun 22 3
13 26409001 Differential ERK activation during autophagy induced by europium hydroxide nanorods and trehalose: Maximum clearance of huntingtin aggregates through combined treatment. 2015 Dec 1
14 24505621 Excitotoxic glutamate insults block autophagic flux in hippocampal neurons. 2014 Jan 13 1
15 24568549 Can trehalose prevent neurodegeneration? Insights from experimental studies. 2014 May 1
16 25412249 Trehalose, an mTOR independent autophagy inducer, alleviates human podocyte injury after puromycin aminonucleoside treatment. 2014 3
17 23997112 Impairment of Atg5-dependent autophagic flux promotes paraquat- and MPP⁺-induced apoptosis but not rotenone or 6-hydroxydopamine toxicity. 2013 Nov 2
18 17182613 Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein. 2007 Feb 23 2