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34560123 | Enhanced GRP78 protein expression via the IRE1α/ASK1/p38 MAPK pathway during As2O3-induced endoplasmic reticulum stress in BEAS-2B cells. | 2021 Oct |
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32318339 | Inhibition of FEN1 Increases Arsenic Trioxide-Induced ROS Accumulation and Cell Death: Novel Therapeutic Potential for Triple Negative Breast Cancer. | 2020 |
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32565734 | Arsenic trioxide potentiates Gilteritinib-induced apoptosis in FLT3-ITD positive leukemic cells via IRE1a-JNK-mediated endoplasmic reticulum stress. | 2020 |
1 |
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30472098 | EVI-1 modulates arsenic trioxide induced apoptosis through JNK signalling pathway in leukemia cells. | 2019 Jan 1 |
3 |
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29266867 | Combination of arsenic trioxide and Dasatinib: a new strategy to treat Philadelphia chromosome-positive acute lymphoblastic leukaemia. | 2018 Mar |
1 |
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28446277 | [Effect of RNA Interference-silenced TAK1 on Kasumi-1 cell Proliferation Inhibition Induced by As2O3 and Its Mechanism]. | 2017 Apr |
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28789348 | Decrease in stathmin expression by arsenic trioxide inhibits the proliferation and invasion of osteosarcoma cells via the MAPK signal pathway. | 2017 Aug |
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29442453 | Transcriptomic analysis of the PI3K/Akt signaling pathway reveals the dual role of the c-Jun oncogene in cytotoxicity and the development of resistance in HL-60 leukemia cells in response to arsenic trioxide. | 2017 Dec |
1 |
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26607805 | Melatonin enhances arsenic trioxide-induced cell death via sustained upregulation of Redd1 expression in breast cancer cells. | 2016 Feb 15 |
2 |
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25791921 | TG-interacting factor transcriptionally induced by AKT/FOXO3A is a negative regulator that antagonizes arsenic trioxide-induced cancer cell apoptosis. | 2015 May 15 |
1 |
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24466103 | Arsenic trioxide induces apoptosis in human platelets via C-Jun NH2-terminal kinase activation. | 2014 |
5 |
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24944602 | Arsenic trioxide induces apoptosis in the THP1 cell line by downregulating EVI-1. | 2014 Jul |
4 |
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23363563 | Genistein ameliorates adverse cardiac effects induced by arsenic trioxide through preventing cardiomyocytes apoptosis. | 2013 |
2 |
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23883479 | Endoplasmic reticulum stress-mediated apoptosis in imatinib-resistant leukemic K562-r cells triggered by AMN107 combined with arsenic trioxide. | 2013 Aug 1 |
1 |
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21946058 | Arsenic trioxide inhibits Ewing's sarcoma cell invasiveness by targeting p38(MAPK) and c-Jun N-terminal kinase. | 2012 Jan |
3 |
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22293863 | MAPK inhibitors and siRNAs differentially affect cell death and ROS levels in arsenic trioxide-treated human pulmonary fibroblast cells. | 2012 May |
2 |
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20799280 | Arsenic trioxide induces apoptosis through JNK and ERK in human mesothelioma cells. | 2011 Mar |
12 |
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21741957 | Arsenic trioxide and radiation enhance apoptotic effects in HL-60 cells through increased ROS generation and regulation of JNK and p38 MAPK signaling pathways. | 2011 Sep 5 |
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21889928 | Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells. Reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation. | 2011 Dec 1 |
3 |
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20074581 | Blockage of JNK pathway enhances arsenic trioxide-induced apoptosis in human keratinocytes. | 2010 Apr 15 |
5 |
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20534739 | Induction of B-chronic lymphocytic leukemia cell apoptosis by arsenic trioxide involves suppression of the phosphoinositide 3-kinase/Akt survival pathway via c-jun-NH2 terminal kinase activation and PTEN upregulation. | 2010 Sep 1 |
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19428345 | Enhancement of esculetin on arsenic trioxide-provoked apoptosis in human leukemia U937 cells. | 2009 Jun 15 |
2 |
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19846917 | The effect of MAPK inhibitors on arsenic trioxide-treated Calu-6 lung cells in relation to cell death, ROS and GSH levels. | 2009 Oct |
3 |
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18210215 | Inhibitory role of TGIF in the As2O3-regulated p21 WAF1/CIP1 expression. | 2008 May |
1 |
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18281123 | A combination of sulindac and arsenic trioxide synergistically induces apoptosis in human lung cancer H1299 cells via c-Jun NH2-terminal kinase-dependent Bcl-xL phosphorylation. | 2008 Sep |
5 |
| 26 |
18412143 | The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells. | 2008 Oct |
6 |
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18695917 | Role of p38 MAPK and JNK in enhanced cervical cancer cell killing by the combination of arsenic trioxide and ionizing radiation. | 2008 Sep |
2 |
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18728151 | Novel human neutrophil agonistic properties of arsenic trioxide: involvement of p38 mitogen-activated protein kinase and/or c-jun NH2-terminal MAPK but not extracellular signal-regulated kinases-1/2. | 2008 Dec |
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18822310 | Arsenic trioxide phosphorylates c-Fos to transactivate p21(WAF1/CIP1) expression. | 2008 Dec 1 |
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17182041 | Involvement of a Rho-ROCK-JNK pathway in arsenic trioxide-induced apoptosis in chronic myelogenous leukemia cells. | 2007 Jan 9 |
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16283431 | Opposite effect of ERK1/2 and JNK on p53-independent p21WAF1/CIP1 activation involved in the arsenic trioxide-induced human epidermoid carcinoma A431 cellular cytotoxicity. | 2006 Jan |
3 |
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16733740 | Role of GSTP1-1 in mediating the effect of As2O3 in the Acute Promyelocytic Leukemia cell line NB4. | 2006 Oct |
1 |
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16734734 | Sustained activation of c-jun-N-terminal kinase plays a critical role in arsenic trioxide-induced cell apoptosis in multiple myeloma cell lines. | 2006 Jun |
9 |
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16972261 | Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis. | 2006 Dec |
1 |
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17384263 | Arsenic trioxide represses NF-kappaB activation and increases apoptosis in ATRA-treated APL cells. | 2006 Dec |
1 |
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15466933 | Trolox selectively enhances arsenic-mediated oxidative stress and apoptosis in APL and other malignant cell lines. | 2005 Feb 1 |
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15637062 | PRAM-1 potentiates arsenic trioxide-induced JNK activation. | 2005 Mar 11 |
3 |
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15817358 | Preferential action of arsenic trioxide in solid-tumor microenvironment enhances radiation therapy. | 2005 Apr 1 |
1 |
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15978632 | Arsenic trioxide induces Hsp70 expression via reactive oxygen species and JNK pathway in MDA231 cells. | 2005 Oct 14 |
6 |
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16184197 | Arsenic trioxide inhibits nuclear receptor function via SEK1/JNK-mediated RXRalpha phosphorylation. | 2005 Oct |
7 |
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16445569 | Inhibition of mitogen-activated protein kinase kinase enhances apoptosis induced by arsenic trioxide in human breast cancer MCF-7 cells. | 2005 Dec |
2 |
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14701702 | JNK activation is a mediator of arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells. | 2004 May 1 |
4 |
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15007384 | Dual effects of glutathione-S-transferase pi on As2O3 action in prostate cancer cells: enhancement of growth inhibition and inhibition of apoptosis. | 2004 May 13 |
2 |
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12754411 | Arsenic trioxide-induced apoptosis is independent of stress-responsive signaling pathways but sensitive to inhibition of inducible nitric oxide synthase in HepG2 cells. | 2003 Apr 30 |
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12931215 | Sustained activation of c-jun-terminal kinase (JNK) is closely related to arsenic trioxide-induced apoptosis in an acute myeloid leukemia (M2)-derived cell line, NKM-1. | 2003 Nov |
3 |
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11150309 | Opposite effect of NF-kappa B and c-Jun N-terminal kinase on p53-independent GADD45 induction by arsenite. | 2001 Apr 6 |
8 |
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11454688 | Tumor growth inhibition by arsenic trioxide (As2O3) in the orthotopic metastasis model of androgen-independent prostate cancer. | 2001 Jul 15 |
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