Dexamethasone

mitogen-activated protein kinase 8 ; Homo sapiens







32 Article(s)
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1 33115754 Therapeutic targeting of pancreatic cancer stem cells by dexamethasone modulation of the MKP-1-JNK axis. 2020 Dec 25 2
2 30897501 Downregulation of microsomal prostaglandin E synthase-1 (mPGES-1) expression in chondrocytes is regulated by MAP kinase phosphatase-1 (MKP-1). 2019 Jun 1
3 28398098 MAPK signaling has stage-dependent osteogenic effects on human adipose-derived stem cells in vitro. 2018 Mar 1
4 28981109 Dexamethasone mediates pancreatic cancer progression by glucocorticoid receptor, TGFβ and JNK/AP-1. 2017 Oct 5 2
5 26101183 Puerarin attenuates glucocorticoid-induced apoptosis of hFOB1.19 cells through the JNK- and Akt-mediated mitochondrial apoptotic pathways. 2015 Aug 2
6 24597985 Low-dose anisomycin sensitizes glucocorticoid-resistant T-acute lymphoblastic leukemia CEM-C1 cells to dexamethasone-induced apoptosis through activation of glucocorticoid receptor and p38-MAPK/JNK. 2014 Sep 2
7 24917907 Dexamethasone Induces Apoptosis of Nasal Polyp-Derived Tissue Cultures Through JNK and p38 MAPK Activation. 2014 Jun 2
8 23871663 Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor κB and c-Jun N-terminal kinase activation. 2013 Nov 1
9 22276160 Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma. 2012 1
10 22401993 Increased corticosteroid sensitivity by a long acting β2 agonist formoterol via β2 adrenoceptor independent protein phosphatase 2A activation. 2012 Jun 1
11 23152905 The plant-derived glucocorticoid receptor agonist Endiandrin A acts as co-stimulator of colonic epithelial sodium channels (ENaC) via SGK-1 and MAPKs. 2012 2
12 18403484 Dexamethasone-induced expression of endothelial mitogen-activated protein kinase phosphatase-1 involves activation of the transcription factors activator protein-1 and 3',5'-cyclic adenosine 5'-monophosphate response element-binding protein and the generation of reactive oxygen species. 2008 Jul 4
13 18437985 [The role of cell pathway in apoptosis of fibroblasts from proliferative scar induced by steroid or IFN]. 2008 Jan 1
14 18441094 Glucocorticoid regulation of CD38 expression in human airway smooth muscle cells: role of dual specificity phosphatase 1. 2008 Jul 1
15 16934508 c-Jun N-terminal kinase mediates constitutive human eosinophil apoptosis. 2007 1
16 17391526 Pathway interactions between MAPKs, mTOR, PKA, and the glucocorticoid receptor in lymphoid cells. 2007 Mar 28 1
17 17513787 Corticosteroid inhibition of growth-related oncogene protein-alpha via mitogen-activated kinase phosphatase-1 in airway smooth muscle cells. 2007 Jun 1 1
18 17568772 Negative regulation of SEK1 signaling by serum- and glucocorticoid-inducible protein kinase 1. 2007 Jul 11 1
19 17581824 Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis. 2007 Aug 17 1
20 17645739 Dexamethasone suppresses interleukin-1beta-induced human beta-defensin 2 mRNA expression: involvement of p38 MAPK, JNK, MKP-1, and NF-kappaB transcriptional factor in A549 cells. 2007 Oct 2
21 15590693 Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival. 2005 Feb 11 1
22 14688340 Dexamethasone inhibits IL-12p40 production in lipopolysaccharide-stimulated human monocytic cells by down-regulating the activity of c-Jun N-terminal kinase, the activation protein-1, and NF-kappa B transcription factors. 2004 Jan 1 3
23 15321787 Fractalkine/CX3CL1 production by human airway smooth muscle cells: induction by IFN-gamma and TNF-alpha and regulation by TGF-beta and corticosteroids. 2004 Dec 1
24 15476200 Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: up-regulation by interleukin-1beta and glucocorticoids. 2004 Oct 2
25 11823508 Distinct role of p38 and c-Jun N-terminal kinases in IL-10-dependent and IL-10-independent regulation of the costimulatory molecule B7.2 in lipopolysaccharide-stimulated human monocytic cells. 2002 Feb 15 3
26 12351702 Nuclear export of glucocorticoid receptor is enhanced by c-Jun N-terminal kinase-mediated phosphorylation. 2002 Oct 1
27 12421945 Differential regulation of CD44 expression by lipopolysaccharide (LPS) and TNF-alpha in human monocytic cells: distinct involvement of c-Jun N-terminal kinase in LPS-induced CD44 expression. 2002 Nov 15 1
28 10974006 Glucocorticoids antagonize AP-1 by inhibiting the Activation/phosphorylation of JNK without affecting its subcellular distribution. 2000 Sep 4 1
29 11012613 Role of caspases in dexamethasone-induced apoptosis and activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase in human eosinophils. 2000 Oct 6
30 10518034 Hormone-activated nuclear receptors inhibit the stimulation of the JNK and ERK signalling pathways in endothelial cells. 1999 Oct 8 4
31 9266970 Dexamethasone induces apoptosis of multiple myeloma cells in a JNK/SAP kinase independent mechanism. 1997 Aug 14 3
32 9343388 Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK. 1997 Nov 2