| 1 |
28683288 | Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance. | 2017 Jul 5 |
2 |
| 2 |
28733206 | Omics-based identification of the combined effects of idiosyncratic drugs and inflammatory cytokines on the development of drug-induced liver injury. | 2017 Oct 1 |
1 |
| 3 |
26698173 | Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE. | 2016 Feb 5 |
1 |
| 4 |
26807955 | Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway. | 2016 |
1 |
| 5 |
25168245 | Stress-induced ceramide generation and apoptosis via the phosphorylation and activation of nSMase1 by JNK signaling. | 2015 Feb |
6 |
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25576381 | C6 ceramide dramatically enhances docetaxel-induced growth inhibition and apoptosis in cultured breast cancer cells: a mechanism study. | 2015 Mar 1 |
2 |
| 7 |
24190701 | Bortezomib-induced apoptosis in cultured pancreatic cancer cells is associated with ceramide production. | 2014 Jan |
2 |
| 8 |
24997497 | Activation of neutral-sphingomyelinase, MAPKs, and p75 NTR-mediating caffeic acid phenethyl ester-induced apoptosis in C6 glioma cells. | 2014 Jul 5 |
1 |
| 9 |
25937892 | Induction of ER stress-mediated apoptosis by ceramide via disruption of ER Ca(2+) homeostasis in human adenoid cystic carcinoma cells. | 2014 |
1 |
| 10 |
23543151 | Role of mitochondrial Bax, caspases, and MAPKs for ceramide-induced apoptosis in renal proximal tubular cells. | 2013 Jul |
1 |
| 11 |
22445853 | Activation of the Hog1p kinase in Isc1p-deficient yeast cells is associated with mitochondrial dysfunction, oxidative stress sensitivity and premature aging. | 2012 May |
1 |
| 12 |
22652149 | Ceramide biosynthesis and metabolism in trophoblast syncytialization. | 2012 Oct 15 |
1 |
| 13 |
22935424 | Endoplasmic reticulum (ER) stress inhibitor salubrinal protects against ceramide-induced SH-SY5Y cell death. | 2012 Oct 26 |
1 |
| 14 |
23065795 | Involvement of de novo ceramide synthesis in gamma-tocopherol and gamma-tocotrienol-induced apoptosis in human breast cancer cells. | 2012 Dec |
2 |
| 15 |
21708940 | Protein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1beta. | 2011 Sep 16 |
1 |
| 16 |
21943220 | c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells. | 2011 Sep 26 |
3 |
| 17 |
20110572 | Nutrient modification of the innate immune response: a novel mechanism by which saturated fatty acids greatly amplify monocyte inflammation. | 2010 Apr |
1 |
| 18 |
21364631 | Role of the JNK/c-Jun/AP-1 signaling pathway in galectin-1-induced T-cell death. | 2010 |
1 |
| 19 |
18820034 | Ceramide activates JNK to inhibit a cAMP-gated K+ conductance and Cl- secretion in intestinal epithelia. | 2009 Jan |
2 |
| 20 |
19029119 | Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy. | 2009 Jan 30 |
1 |
| 21 |
19060920 | The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells. | 2009 Feb 12 |
3 |
| 22 |
19337026 | Ceramide-induced autophagy: to junk or to protect cells? | 2009 May |
2 |
| 23 |
18270325 | Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway. | 2008 Apr 15 |
5 |
| 24 |
18948750 | Ceramide promotes apoptosis in chronic myelogenous leukemia-derived K562 cells by a mechanism involving caspase-8 and JNK. | 2008 Nov 1 |
3 |
| 25 |
17005604 | Advanced glycation end products induce apoptosis in fibroblasts through activation of ROS, MAP kinases, and the FOXO1 transcription factor. | 2007 Feb |
1 |
| 26 |
17828457 | Apoptosis induced by capsaicin in prostate PC-3 cells involves ceramide accumulation, neutral sphingomyelinase, and JNK activation. | 2007 Nov |
2 |
| 27 |
16413574 | Activation of JNK and xanthine oxidase by TNF-alpha impairs nitric oxide-mediated dilation of coronary arterioles. | 2006 Feb |
1 |
| 28 |
16479073 | Ceramides and cell signaling molecules in psoriatic epidermis: reduced levels of ceramides, PKC-alpha, and JNK. | 2006 Feb |
2 |
| 29 |
16524368 | Amyloid beta peptide increases DP5 expression via activation of neutral sphingomyelinase and JNK in oligodendrocytes. | 2006 May |
8 |
| 30 |
16969513 | Paclitaxel and ceramide synergistically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells. | 2006 Oct |
1 |
| 31 |
15769735 | UV-C light induces raft-associated acid sphingomyelinase and JNK activation and translocation independently on a nuclear signal. | 2005 May 13 |
4 |
| 32 |
15905098 | Ceramide induces neuronal apoptosis through mitogen-activated protein kinases and causes release of multiple mitochondrial proteins. | 2005 Jul |
1 |
| 33 |
15520191 | Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal kinase. | 2004 Nov 1 |
8 |
| 34 |
12646059 | Signaling mechanisms in tumor necrosis factor alpha-induced death of microvascular endothelial cells of the corpus luteum. | 2003 Feb 11 |
1 |
| 35 |
12676512 | Intracellular signal transduction pathways activated by ceramide and its metabolites. | 2003 May |
1 |
| 36 |
12738796 | Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors. | 2003 Jul 18 |
3 |
| 37 |
12770554 | C-Jun N-terminal kinases/c-Jun and p38 pathways cooperate in ceramide-induced neuronal apoptosis. | 2003 |
1 |
| 38 |
12504027 | Activation of the Drosophila MLK by ceramide reveals TNF-alpha and ceramide as agonists of mammalian MLK3. | 2002 Dec |
1 |
| 39 |
11181043 | UVA radiation stimulates ceramide production: relationship to oxidative stress and potential role in ERK, JNK, and p38 activation. | 2001 Feb 23 |
1 |
| 40 |
11241551 | Ceramide-induced cell death in the prostate cancer cell line LNCaP has both necrotic and apoptotic features. | 2001 Mar 1 |
2 |
| 41 |
11354249 | Cell line dependent involvement of ceramide in ultraviolet light-induced apoptosis. | 2001 Mar |
4 |
| 42 |
11480555 | Ceramide regulates cellular homeostasis via diverse stress signaling pathways. | 2001 Aug |
2 |
| 43 |
10666416 | Rapid activation of neutral sphingomyelinase by hypoxia-reoxygenation of cardiac myocytes. | 2000 Feb 4 |
2 |
| 44 |
10788436 | Protein tyrosine kinase p56lck is required for ceramide-induced but not tumor necrosis factor-induced activation of NF-kappa B, AP-1, JNK, and apoptosis. | 2000 May 5 |
2 |
| 45 |
10903735 | Fas ligand-induced c-Jun kinase activation in lymphoid cells requires extensive receptor aggregation but is independent of DAXX, and Fas-mediated cell death does not involve DAXX, RIP, or RAIDD. | 2000 Aug 1 |
1 |
| 46 |
10919278 | Dexamethasone suppresses tumor necrosis factor-alpha-induced apoptosis in osteoblasts: possible role for ceramide. | 2000 Aug |
1 |
| 47 |
11001916 | Lipopolysaccharide induces jun N-terminal kinase activation in macrophages by a novel Cdc42/Rac-independent pathway involving sequential activation of protein kinase C zeta and phosphatidylcholine-dependent phospholipase C. | 2000 Oct 1 |
1 |
| 48 |
11152959 | Ceramide-dependent regulation of p42/p44 mitogen-activated protein kinase and c-Jun N-terminal-directed protein kinase in cultured airway smooth muscle cells. | 2000 Dec |
2 |
| 49 |
10340476 | Suppression of ceramide-mediated apoptosis by HSP70. | 1999 Apr 30 |
1 |
| 50 |
10531389 | Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin. | 1999 Nov |
2 |