2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

mitogen-activated protein kinase 8 ; Homo sapiens







87 Article(s)
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1 34395234 Suppression of Tumorigenicity 5 Ameliorates Tumor Characteristics of Invasive Breast Cancer Cells via ERK/JNK Pathway. 2021 1
2 32174780 Suppressive effects of S100A8 and S100A9 on neutrophil apoptosis by cytokine release of human bronchial epithelial cells in asthma. 2020 1
3 33157237 MMP-1 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells via the JNK and ERK pathway. 2020 Dec 2
4 30461130 Extracellular matrix remodeling effects of serum amyloid A1 in the human amnion: Implications for fetal membrane rupture. 2019 Jan 1
5 29770357 MAPK Pathway Involved in Epidermal Terminal Differentiation of Normal Human Epidermal Keratinocytes. 2018 1
6 30073566 Hyperbaric Oxygen Alleviates the Inflammatory Response Induced by LPS Through Inhibition of NF-κB/MAPKs-CCL2/CXCL1 Signaling Pathway in Cultured Astrocytes. 2018 Dec 1
7 30317802 [Role of MAPK signaling pathway in epithelial-mesenchymal transition of type II alveolar epithelial cells induced by Paraquat]. 2018 Aug 20 1
8 28223944 IL-1β-Induced Downregulation of the Multifunctional PDZ Adaptor PDZK1 Is Attenuated by ERK Inhibition, RXRα, or PPARα Stimulation in Enterocytes. 2017 1
9 28945007 Nonmineralized and Mineralized Collagen Scaffolds Induce Differential Osteogenic Signaling Pathways in Human Mesenchymal Stem Cells. 2017 Dec 1
10 26084532 Early Growth Response Protein-1 Expression by Insulin-Like Growth Factor-1 Requires ROS-Dependent Activation of ERK1/2 and PKB Pathways in Vascular Smooth Muscle Cells. 2016 Jan 1
11 26932601 Exendin-4 promotes proliferation of adipose-derived stem cells through ERK and JNK signaling pathways. 2016 May 2
12 27216486 Disinhibition of the extracellular-signal-regulated kinase restores the amplification of circadian rhythms by lithium in cells from bipolar disorder patients. 2016 Aug 2
13 25399887 Effect of inflammatory factor-induced cyclo-oxygenase expression on the development of reperfusion-related no-reflow phenomenon in acute myocardial infarction. 2015 Feb 1
14 26086160 Reactive oxygen species mediate nitric oxide production through ERK/JNK MAPK signaling in HAPI microglia after PFOS exposure. 2015 Oct 15 1
15 23805815 Hypoxia regulates the proliferation and osteogenic differentiation of human periodontal ligament cells under cyclic tensile stress via mitogen-activated protein kinase pathways. 2014 Mar 1
16 24055274 AMPK activator-mediated inhibition of endoplasmic reticulum stress ameliorates carrageenan-induced insulin resistance through the suppression of selenoprotein P in HepG2 hepatocytes. 2014 Jan 25 1
17 22006557 Involvement of mitogen-activated protein kinase in signal transducer and activator of transcription-1 mediated differentiation induced by bortezomib in acute myeloid leukemia cells. 2013 Jan 1
18 23135225 Vaspin attenuates the apoptosis of human osteoblasts through ERK signaling pathway. 2013 Mar 1
19 23237828 Cycloheximide stimulates suppressor of cytokine signaling-3 gene expression in 3T3-L1 adipocytes via the extracellular signal-regulated kinase pathway. 2013 Feb 13 1
20 23405080 Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation. 2013 1
21 23490067 Arachidonic acid enhances TPA-induced differentiation in human leukemia HL-60 cells via reactive oxygen species-dependent ERK activation. 2013 Apr 2
22 22172327 Active lipids of Ganoderma lucidum spores-induced apoptosis in human leukemia THP-1 cells via MAPK and PI3K pathways. 2012 Jan 31 1
23 22173130 Cobalt(II) β-ketoaminato complexes as novel inhibitors of neuroinflammation. 2012 Feb 15 2
24 22314224 Ginsenoside Rh1 suppresses matrix metalloproteinase-1 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathway in human hepatocellular carcinoma cells. 2012 Mar 15 1
25 21082355 Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism. 2011 Feb 1
26 21647617 Effects of downregulation of aquaporin1 by peptidoglycan and lipopolysaccharide via MAPK pathways in MeT-5A cells. 2011 Aug 1
27 19882352 Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling. 2010 Feb 1
28 20103766 Induction of neutrophil degranulation by S100A9 via a MAPK-dependent mechanism. 2010 May 1
29 20458747 12-O-tetradecanoylphorbol-13-acetate-induced invasion/migration of glioblastoma cells through activating PKCalpha/ERK/NF-kappaB-dependent MMP-9 expression. 2010 Nov 3
30 20538278 Angiotensin II induces C-reactive protein expression through ERK1/2 and JNK signaling in human aortic endothelial cells. 2010 Sep 1
31 20627382 Vasoactive intestinal peptide induces vascular endothelial growth factor production in human HaCaT keratinocytes via MAPK pathway. 2010 Oct 1
32 21131736 [Regulatory mechanism of activator protein-1 on the expression of MUC5AC induced by cigarette smoke extract]. 2010 Nov 2
33 19223550 LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors. 2009 Mar 1 2
34 19288033 Trans-Zeatin inhibits UVB-induced matrix metalloproteinase-1 expression via MAP kinase signaling in human skin fibroblasts. 2009 Apr 2
35 19522739 Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer. 2009 Aug 1
36 19651223 Calcitonin gene-related peptide increases proliferation of human HaCaT keratinocytes by activation of MAP kinases. 2009 Nov 1
37 19657566 TGF-beta promotes invasion and metastasis of gastric cancer cells by increasing fascin1 expression via ERK and JNK signal pathways. 2009 Aug 1
38 17934787 JNK and ERK mitogen-activated protein kinases mediate THDA-induced apoptosis in K562 cells. 2008 Aug 1
39 18068334 Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2. 2008 Feb 1
40 18385943 The JNK/AP1/ATF2 pathway is involved in H2O2-induced acetylcholinesterase expression during apoptosis. 2008 May 2
41 18403484 Dexamethasone-induced expression of endothelial mitogen-activated protein kinase phosphatase-1 involves activation of the transcription factors activator protein-1 and 3',5'-cyclic adenosine 5'-monophosphate response element-binding protein and the generation of reactive oxygen species. 2008 Jul 1
42 18639962 Activation of MAPK participates in low shear stress-induced IL-8 gene expression in endothelial cells. 2008 2
43 17251521 Signaling pathways regulating IL-1alpha-induced COX-2 expression. 2007 Feb 1
44 17289100 Biphasic effect of arsenite on cell proliferation and apoptosis is associated with the activation of JNK and ERK1/2 in human embryo lung fibroblast cells. 2007 Apr 1 1
45 17457195 Hyperosmolarity-induced apoptosis in human corneal epithelial cells is mediated by cytochrome c and MAPK pathways. 2007 May 1
46 17940558 [Regulation of promatrilysin expression by tissue factor/actived coagulation factor VII complex in LoVo colon cancer cell line]. 2007 Oct 18 1
47 16202406 JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells. 2006 Apr 1
48 16328781 Hyperbaric oxygen induces VEGF expression through ERK, JNK and c-Jun/AP-1 activation in human umbilical vein endothelial cells. 2006 Jan 1
49 16480952 Differentiation-associated genes regulated by TPA-induced c-Jun expression via a PKC/JNK pathway in KYSE450 cells. 2006 Mar 31 1
50 16564547 Differential transcriptional responses of keloid and normal keratinocytes to serum stimulation. 2006 Sep 1