Sorafenib

mitogen-activated protein kinase 8 ; Homo sapiens







28 Article(s)
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1 35129807 Zinc supplementation ameliorates sorafenib-induced cognitive impairment through ROS/JNK signaling pathway. 2022 Feb 7 1
2 33667419 Computational model of cardiomyocyte apoptosis identifies mechanisms of tyrosine kinase inhibitor-induced cardiotoxicity. 2021 Jun 1
3 34332981 Dichloroacetate enhances the anti-tumor effect of sorafenib via modulating the ROS-JNK-Mcl-1 pathway in liver cancer cells. 2021 Sep 1 4
4 34767735 RABL2A-CCDC34 Axis Promotes Sorafenib Resistance in Hepatocellular Carcinoma. 2021 Nov 1
5 32636042 Retraction notice to "Cytokine augments the sorafenib-induced apoptosis in Huh7 liver cancer cell by inducing mitochondrial fragmentation and activating MAPK-JNK signalling pathway" [Biomed. Pharmacother. 110 (2019) 213-223]. 2020 Sep 1
6 30476722 Cytokine augments the sorafenib-induced apoptosis in Huh7 liver cancer cell by inducing mitochondrial fragmentation and activating MAPK-JNK signalling pathway. 2019 Feb 3
7 29864454 RASSF6-mediated inhibition of Mcl-1 through JNK activation improves the anti-tumor effects of sorafenib in renal cell carcinoma. 2018 Sep 28 3
8 29928452 Luteolin and sorafenib combination kills human hepatocellular carcinoma cells through apoptosis potentiation and JNK activation. 2018 Jul 2
9 30132846 Molecular characterization of autophagic and apoptotic signaling induced by sorafenib in liver cancer cells. 2018 Jan 1
10 30187994 Synergistic antimetastatic effect of cotreatment with licochalcone A and sorafenib on human hepatocellular carcinoma cells through the inactivation of MKK4/JNK and uPA expression. 2018 Dec 1
11 30443188 The HDAC Inhibitor Quisinostat (JNJ-26481585) Supresses Hepatocellular Carcinoma alone and Synergistically in Combination with Sorafenib by G0/G1 phase arrest and Apoptosis induction. 2018 1
12 30459526 IL-2 augments the sorafenib-induced apoptosis in liver cancer by promoting mitochondrial fission and activating the JNK/TAZ pathway. 2018 5
13 28055301 Autophagy orchestrates adaptive responses to targeted therapy in endometrial cancer. 2017 Mar 4 1
14 28178378 Melatonin promotes sorafenib-induced apoptosis through synergistic activation of JNK/c-jun pathway in human hepatocellular carcinoma. 2017 Apr 3
15 29033791 Protein Synthesis Inhibition and Activation of the c-Jun N-Terminal Kinase Are Potential Contributors to Cisplatin Ototoxicity. 2017 1
16 26629768 Sorafenib induces autophagic cell death and apoptosis in hepatic stellate cell through the JNK and Akt signaling pathways. 2016 Mar 2
17 26964667 Activation of c-Jun predicts a poor response to sorafenib in hepatocellular carcinoma: Preliminary Clinical Evidence. 2016 Mar 11 1
18 25683251 Activation of AMP-activated protein kinase by retinoic acid sensitizes hepatocellular carcinoma cells to apoptosis induced by sorafenib. 2015 May 1
19 26460271 Sorafenib inhibits cancer side population cells by targeting c‑Jun N‑terminal kinase signaling. 2015 Dec 4
20 26517516 Identification of the β-catenin/JNK/prothymosin-alpha axis as a novel target of sorafenib in hepatocellular carcinoma cells. 2015 Nov 17 1
21 24170769 Sorafenib suppresses JNK-dependent apoptosis through inhibition of ZAK. 2014 Jan 4
22 24402682 ROS-mediated JNK/p38-MAPK activation regulates Bax translocation in Sorafenib-induced apoptosis of EBV-transformed B cells. 2014 Mar 1
23 24726537 Sorafenib resistance and JNK signaling in carcinoma during extracellular matrix stiffening. 2014 Jul 1
24 25245054 Metformin inhibits the invasion of human hepatocellular carcinoma cells and enhances the chemosensitivity to sorafenib through a downregulation of the ERK/JNK-mediated NF-κB-dependent pathway that reduces uPA and MMP-9 expression. 2014 Dec 1
25 22596232 Activation of JNK and high expression level of CD133 predict a poor response to sorafenib in hepatocellular carcinoma. 2012 Jun 5 6
26 20301194 Sorafenib combined vitamin K induces apoptosis in human pancreatic cancer cell lines through RAF/MEK/ERK and c-Jun NH2-terminal kinase pathways. 2010 Jul 3
27 21062976 Induction of DNA damage-inducible gene GADD45beta contributes to sorafenib-induced apoptosis in hepatocellular carcinoma cells. 2010 Nov 15 4
28 16985072 Cytotoxic synergy between the multikinase inhibitor sorafenib and the proteasome inhibitor bortezomib in vitro: induction of apoptosis through Akt and c-Jun NH2-terminal kinase pathways. 2006 Sep 2