Vinblastine

mitogen-activated protein kinase 8 ; Homo sapiens







16 Article(s)
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1 25914345 JNK and NFκB dependence of apoptosis induced by vinblastine in human acute promyelocytic leukaemia cells. 2015 Jun 4
2 20510207 Up-regulation of connexin 32 gene by 5-aza-2'-deoxycytidine enhances vinblastine-induced cytotoxicity in human renal carcinoma cells via the activation of JNK signalling. 2010 Aug 15 1
3 19427996 Regulation of Bax by c-Jun NH2-terminal kinase and Bcl-xL in vinblastine-induced apoptosis. 2009 Aug 1 5
4 19674193 Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response. 2009 Sep 2
5 18341588 Distinct signaling pathways of microtubule inhibitors--vinblastine and Taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively. 2008 Apr 4
6 17126817 Inducible overexpression of c-Jun in MCF7 cells causes resistance to vinblastine via inhibition of drug-induced apoptosis and senescence at a step subsequent to mitotic arrest. 2007 Feb 15 1
7 16555127 Effect of vinca alkaloids on ERalpha levels and estradiol-induced responses in MCF-7 cells. 2006 Jul 2
8 12907245 The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide. 2003 Aug 1 1
9 12121974 Gamma-synuclein promotes cancer cell survival and inhibits stress- and chemotherapy drug-induced apoptosis by modulating MAPK pathways. 2002 Sep 20 2
10 12221076 Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells. 2002 Nov 15 1
11 11245462 Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells. 2001 Feb 15 10
12 10623471 Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells. 2000 Jan 10 1
13 10913135 Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade. 2000 Sep 29 9
14 11103805 Modulation of mitogen-activated protein kinases and phosphorylation of Bcl-2 by vinblastine represent persistent forms of normal fluctuations at G2-M1. 2000 Nov 15 1
15 9478937 Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways. 1998 Feb 27 1
16 8940082 Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs. 1996 Nov 29 2