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mitogen-activated protein kinase 8 ; Homo sapiens







36 Article(s)
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1 23418897 Involvement of c-Jun N-terminal kinase in reversal of multidrug resistance of human leukemia cells in hypoxia by 5-bromotetrandrine. 2013 Nov 2
2 21461383 Non-viral systemic delivery of siRNA or antisense oligonucleotides targeted to Jun N-terminal kinase 1 prevents cellular hypoxic damage. 2011 Feb 1
3 18767140 Activation of JNK and PAK2 is essential for citrinin-induced apoptosis in a human osteoblast cell line. 2009 Aug 3
4 19161988 The NF kappa B-mediated control of RS and JNK signaling in vitamin A-treated cells: duration of JNK-AP-1 pathway activation may determine cell death or proliferation. 2009 Apr 1 1
5 18403484 Dexamethasone-induced expression of endothelial mitogen-activated protein kinase phosphatase-1 involves activation of the transcription factors activator protein-1 and 3',5'-cyclic adenosine 5'-monophosphate response element-binding protein and the generation of reactive oxygen species. 2008 Jul 1
6 18480747 Induction of proapoptotic Daxx following ischemic acute kidney injury. 2008 Aug 1
7 18541008 JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis. 2008 Aug 1
8 15970429 High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway. 2006 Mar 1
9 16889436 JNK1 as a molecular target to limit cellular mortality under hypoxia. 2006 Jul-Aug 1
10 17299580 Proteomic analysis of mechanisms of hypoxia-induced apoptosis in trophoblastic cells. 2006 Dec 29 2
11 15677475 Preheating accelerates mitogen-activated protein (MAP) kinase inactivation post-heat shock via a heat shock protein 70-mediated increase in phosphorylated MAP kinase phosphatase-1. 2005 Apr 1 1
12 14699495 Cyclooxygenase-2 inhibitor (SC-236) suppresses activator protein-1 through c-Jun NH2-terminal kinase. 2004 Jan 3
13 14724588 Inhibition of JNK reduces G2/M transit independent of p53, leading to endoreduplication, decreased proliferation, and apoptosis in breast cancer cells. 2004 Jan 15 2
14 15195070 Paraptosis: mediation by MAP kinases and inhibition by AIP-1/Alix. 2004 Oct 2
15 12538493 C-Jun NH(2)-terminal kinase mediates proliferation and tumor growth of human prostate carcinoma. 2003 Jan 2
16 12619033 Requirement of c-jun for testosterone-induced sensitization to N-(4-hydroxyphenyl)retinamide-induced apoptosis. 2003 Mar 1
17 12760970 C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts. 2003 Jun 1
18 12847227 c-Jun N-terminal kinase negatively regulates lipopolysaccharide-induced IL-12 production in human macrophages: role of mitogen-activated protein kinase in glutathione redox regulation of IL-12 production. 2003 Jul 15 3
19 14532296 Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1. 2003 Dec 26 4
20 14611688 Specificity in stress response: epidermal keratinocytes exhibit specialized UV-responsive signal transduction pathways. 2003 Oct 1
21 12049842 Microtubule damaging agents induce apoptosis in HL 60 cells and G2/M cell cycle arrest in HT 29 cells. 2002 Jun 14 3
22 12183452 Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine. 2002 Oct 18 1
23 12221076 Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells. 2002 Nov 15 1
24 11160861 Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 Cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells. 2001 Feb 2
25 11278982 c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation. 2001 May 11 1
26 10704932 Inhibition of hypoxia/reoxygenation-induced apoptosis by an antisense oligonucleotide targeted to JNK1 in human kidney cells. 2000 May 1 7
27 10839298 Activation of SAPK/JNK by camptothecin sensitizes androgen-independent prostate cancer cells to Fas-induced apoptosis. 2000 Jun 1
28 10840014 High glucose-induced apoptosis in human endothelial cells is mediated by sequential activations of c-Jun NH(2)-terminal kinase and caspase-3. 2000 Jun 6 1
29 10998365 Apoptotic signalling cascade in photosensitized human epidermal carcinoma A431 cells: involvement of singlet oxygen, c-Jun N-terminal kinase, caspase-3 and p21-activated kinase 2. 2000 Oct 1 3
30 11103806 The role of c-Jun kinase in the apoptotic response to nucleoside analogue-induced DNA damage. 2000 Nov 15 2
31 9927052 Activation of c-Jun NH2-terminal kinase and subsequent CPP32/Yama during topoisomerase inhibitor beta-lapachone-induced apoptosis through an oxidation-dependent pathway. 1999 Jan 15 2
32 10200552 IL-2 deprivation triggers apoptosis which is mediated by c-Jun N-terminal kinase 1 activation and prevented by Bcl-2. 1999 Jan 1
33 9790925 Interleukin-1 beta and reactive oxygen species mediate activation of c-Jun NH2-terminal kinases, in human epithelial cells, by two independent pathways. 1998 Oct 9 1
34 9020192 c-Jun NH2-terminal kinase-mediated activation of interleukin-1beta converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis. 1997 Feb 14 3
35 9115218 Hypoglycemia-induced c-Jun phosphorylation is mediated by c-Jun N-terminal kinase 1 and Lyn kinase in drug-resistant human breast carcinoma MCF-7/ADR cells. 1997 May 2 1
36 9407138 The JUN kinase/stress-activated protein kinase pathway is required for epidermal growth factor stimulation of growth of human A549 lung carcinoma cells. 1997 Dec 26 3