Cisplatin

mitogen-activated protein kinase 8 ; Homo sapiens







140 Article(s)
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51 27659012 Induction of Activating Transcription Factor 3 Is Associated with Cisplatin Responsiveness in Non-Small Cell Lung Carcinoma Cells. 2016 Sep 2
52 27751820 Inhibition of JNK and prothymosin-alpha sensitizes hepatocellular carcinoma cells to cisplatin. 2016 Dec 15 4
53 27779694 Fentanyl induces autophagy via activation of the ROS/MAPK pathway and reduces the sensitivity of cisplatin in lung cancer cells. 2016 Dec 1
54 27825085 AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1. IMPLICATION OF AKT2 IN CHEMORESISTANCE. 2016 Oct 21 1
55 28101169 Role of Wnt/β-catenin, Wnt/c-Jun N-terminal kinase and Wnt/Ca2+ pathways in cisplatin-induced chemoresistance in ovarian cancer. 2016 Dec 1
56 25351964 Inhibition of basal JNK activity by small interfering RNAs enhances cisplatin sensitivity and decreases DNA repair in T98G glioblastoma cells. 2015 Jan 1
57 25563368 FOXM1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and mediates sensitivity to cisplatin in A549 cells via the JNK/mitochondrial pathway. 2015 3
58 25682199 Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIPL degradation, Ripoptosome formation and autophagy-mediated apoptosis. 2015 Jan 30 1
59 25793618 Alpha-catulin contributes to drug-resistance of melanoma by activating NF-κB and AP-1. 2015 1
60 26049416 APC selectively mediates response to chemotherapeutic agents in breast cancer. 2015 Jun 7 1
61 26118633 Saikosaponin-D reduces cisplatin-induced nephrotoxicity by repressing ROS-mediated activation of MAPK and NF-κB signalling pathways. 2015 Sep 1
62 26592553 MLN4924 Synergistically Enhances Cisplatin-induced Cytotoxicity via JNK and Bcl-xL Pathways in Human Urothelial Carcinoma. 2015 Nov 23 4
63 23543357 Apoptotic effect of cisplatin and cordycepin on OC3 human oral cancer cells. 2014 Aug 2
64 23584473 PKA/Smurf1 signaling-mediated stabilization of Nur77 is required for anticancer drug cisplatin-induced apoptosis. 2014 Mar 27 1
65 24675421 Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition. 2014 Mar 15 5
66 24686174 E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin. 2014 Apr 15 4
67 24865582 Upregulation of miR-21 in cisplatin resistant ovarian cancer via JNK-1/c-Jun pathway. 2014 3
68 25006835 Comparison of Intracellular Stress Response of NCI-H526 Small Cell Lung Cancer (SCLC) Cells to Platinum(II) Cisplatin and Platinum(IV) Oxoplatin. 2014 Jul 8 1
69 25028967 Downregulation of Ras association domain family member 6 (RASSF6) underlies the treatment resistance of highly metastatic nasopharyngeal carcinoma cells. 2014 1
70 25152024 Mig-2 attenuates cisplatin-induced apoptosis of human glioma cells in vitro through AKT/JNK and AKT/p38 signaling pathways. 2014 Sep 2
71 23103562 TNF-α-mediated NF-κB survival signaling impairment by cisplatin enhances JNK activation allowing synergistic apoptosis of renal proximal tubular cells. 2013 Jan 15 3
72 23720056 TR3 modulates platinum resistance in ovarian cancer. 2013 Aug 1 2
73 23817665 β-Elemene enhances susceptibility to cisplatin in resistant ovarian carcinoma cells via downregulation of ERCC-1 and XIAP and inactivation of JNK. 2013 Sep 2
74 23886095 [Thrichosanthin enhances cisplatin-induced laryngocarcinoma apoptosis through inhibiting transcription factor nuclear factor κB]. 2013 Apr 3
75 23900581 Modulation of the response of prostate cancer cell lines to cisplatin treatment using small interfering RNA. 2013 Oct 3
76 23929259 Signalling mechanisms involved in renal pathological changes during cisplatin-induced nephropathy. 2013 Nov 1
77 24055030 MUC1 activates JNK1 and inhibits apoptosis under genotoxic stress. 2013 Oct 11 2
78 24115572 Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK. 2013 Nov 2
79 21684138 Sulforaphane, a natural constituent of broccoli, prevents cell death and inflammation in nephropathy. 2012 May 3
80 22142405 The response of human ectomesenchymal dental pulp stem cells to cisplatin treatment. 2012 May 2
81 22900074 TAp73-mediated the activation of c-Jun N-terminal kinase enhances cellular chemosensitivity to cisplatin in ovarian cancer cells. 2012 3
82 21324906 Late activation of stress-activated protein kinases/c-Jun N-terminal kinases triggered by cisplatin-induced DNA damage in repair-defective cells. 2011 Apr 15 5
83 21857081 Anti-apoptotic effect of phloretin on cisplatin-induced apoptosis in HEI-OC1 auditory cells. 2011 1
84 19910452 Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells. 2010 Feb 1
85 20106899 Glutathione transferase omega 1-1 (GSTO1-1) plays an anti-apoptotic role in cell resistance to cisplatin toxicity. 2010 May 1
86 19258036 Phospholipase A2-activating protein (PLAA) enhances cisplatin-induced apoptosis in HeLa cells. 2009 Jul 2
87 19471112 Cisplatin reduces endothelial cell migration via regulation of type 2-matrix metalloproteinase activity. 2009 2
88 19723115 Effect of epidermal growth factor receptor inhibitor alone and in combination with cisplatin on growth of vulvar cancer cells. 2009 Aug 2
89 19787270 Selectivity analysis of protein kinase CK2 inhibitors DMAT, TBB and resorufin in cisplatin-induced stress responses. 2009 Nov 2
90 18093981 A sensitive flow cytometry-based nucleotide excision repair assay unexpectedly reveals that mitogen-activated protein kinase signaling does not regulate the removal of UV-induced DNA damage in human cells. 2008 Feb 29 1
91 18249159 ATF3 and Fra1 have opposite functions in JNK- and ERK-dependent DNA damage responses. 2008 Mar 1 5
92 18331824 Short interfering RNA directed against TWIST, a novel zinc finger transcription factor, increases A549 cell sensitivity to cisplatin via MAPK/mitochondrial pathway. 2008 May 16 2
93 18372076 Knockdown of Snail, a novel zinc finger transcription factor, via RNA interference increases A549 cell sensitivity to cisplatin via JNK/mitochondrial pathway. 2008 Oct 3
94 18391982 Cancer-specific enhancement of cisplatin-induced cytotoxicity with triptolide through an interaction of inactivated glycogen synthase kinase-3beta with p53. 2008 Jul 31 2
95 18726921 High level of mitogen-activated protein kinase phosphatase-1 expression is associated with cisplatin resistance in osteosarcoma. 2008 Dec 1
96 17283157 Sensitizing effect of galectin-7 in urothelial cancer to cisplatin through the accumulation of intracellular reactive oxygen species. 2007 Feb 1 1
97 17409444 Enhanced expression of asparagine synthetase under glucose-deprived conditions protects pancreatic cancer cells from apoptosis induced by glucose deprivation and cisplatin. 2007 Apr 1 1
98 17418561 Piperine protects cisplatin-induced apoptosis via heme oxygenase-1 induction in auditory cells. 2007 Sep 1
99 17586463 Epstein-Barr virus-encoded LMP1 promotes cisplatin-induced caspase activation through JNK and NF-kappaB signaling pathways. 2007 Aug 17 3
100 16462770 MKP1/CL100 controls tumor growth and sensitivity to cisplatin in non-small-cell lung cancer. 2006 Jun 1 3