Cisplatin

mitogen-activated protein kinase 8 ; Homo sapiens







140 Article(s)
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1 35001794 The urinary exosomes derived from premature infants attenuate cisplatin-induced acute kidney injury in mice via microRNA-30a-5p/ mitogen-activated protein kinase 8 (MAPK8). 2022 Jan 2
2 35179434 Circ_0067934 reduces JNK phosphorylation through a microRNA-545-3p/PPA1 axis to enhance tumorigenesis and cisplatin resistance in ovarian cancer. 2022 Apr 1
3 35236965 STAMBPL1 promotes breast cancer cell resistance to cisplatin partially by stabilizing MKP-1 expression. 2022 Apr 2
4 35251480 Glaucocalyxin B Attenuates Ovarian Cancer Cell Growth and Cisplatin Resistance In Vitro via Activating Oxidative Stress. 2022 2
5 35578316 SCARA3 inhibits cell proliferation and EMT through AKT signaling pathway in lung cancer. 2022 May 16 1
6 33456714 Correction: Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals. 2021 Jan 5 1
7 33460665 RIPK1 contributes to cisplatin-induced apoptosis of esophageal squamous cell carcinoma cells via activation of JNK pathway. 2021 Mar 15 1
8 33921192 Resveratrol Enhances Inhibition Effects of Cisplatin on Cell Migration and Invasion and Tumor Growth in Breast Cancer MDA-MB-231 Cell Models In Vivo and In Vitro. 2021 Apr 12 1
9 33959604 Isoalantolactone Increases the Sensitivity of Prostate Cancer Cells to Cisplatin Treatment by Inducing Oxidative Stress. 2021 1
10 33973461 The new-generation proteasome inhibitor oprozomib increases the sensitivity of cervical cancer cells to cisplatin-induced apoptosis. 2021 Mar-Apr 1
11 33990641 trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway. 2021 May 14 1
12 34274415 Cisplatin induces autophagy-associated apoptosis in human oral squamous cell carcinoma (OSCC) mediated in part through reactive oxygen species. 2021 Sep 15 1
13 34306367 CHOP overexpression sensitizes human non-small cell lung cancer cells to cisplatin treatment by Bcl-2/JNK pathway. 2021 3
14 34533242 Rosamultin from Potentilla anserine L. exhibits nephroprotection and antioxidant activity by regulating the reactive oxygen species/C/EBP homologous protein signaling pathway. 2021 Nov 1
15 34790784 TRPA1 promotes cisplatin-induced nephrotoxicity through inflammation mediated by the MAPK/NF-κB signaling pathway. 2021 Oct 1
16 32238696 Pro-apoptotic functions of TRAF2 in p53-mediated apoptosis induced by cisplatin. 2020 2
17 32277442 A comparative molecular analysis of DNA damage response, cell cycle progression, viability and apoptosis of malignant granulosa cells exposed to gemcitabine and cisplatin. 2020 May 1
18 32308804 Plumbagin Enhances the Anticancer Efficacy of Cisplatin by Increasing Intracellular ROS in Human Tongue Squamous Cell Carcinoma. 2020 1
19 32341033 DGKA Provides Platinum Resistance in Ovarian Cancer Through Activation of c-JUN-WEE1 Signaling. 2020 Jul 15 1
20 32533982 Enhanced expression of lncRNA ZXF1 promotes cisplatin resistance in lung cancer cell via MAPK axis. 2020 Oct 1
21 32695207 Ginsenoside Rh1 Alleviates HK-2 Apoptosis by Inhibiting ROS and the JNK/p53 Pathways. 2020 1
22 32781170 Hydroxytyrosol enhances cisplatin-induced ototoxicity: Possible relation to the alteration in the activity of JNK and AIF pathways. 2020 Nov 15 1
23 32884297 MiR-140 Resensitizes Cisplatin-Resistant NSCLC Cells to Cisplatin Treatment Through the SIRT1/ROS/JNK Pathway. 2020 4
24 33072762 Isodeoxyelephantopin Inactivates Thioredoxin Reductase 1 and Activates ROS-Mediated JNK Signaling Pathway to Exacerbate Cisplatin Effectiveness in Human Colon Cancer Cells. 2020 1
25 30614075 Core fucosylation of copper transporter 1 plays a crucial role in cisplatin-resistance of epithelial ovarian cancer by regulating drug uptake. 2019 May 1
26 30868675 Cancer-associated fibroblasts contribute to cisplatin resistance by modulating ANXA3 in lung cancer cells. 2019 May 3
27 30922965 PDIA6 modulates apoptosis and autophagy of non-small cell lung cancer cells via the MAP4K1/JNK signaling pathway. 2019 Apr 1
28 31056532 MiR-124 sensitizes cisplatin-induced cytotoxicity against CD133+ hepatocellular carcinoma cells by targeting SIRT1/ROS/JNK pathway. 2019 May 5 2
29 31176737 Curcuminoid WZ26, a TrxR1 inhibitor, effectively inhibits colon cancer cell growth and enhances cisplatin-induced cell death through the induction of ROS. 2019 Sep 2
30 31929796 Screening of Pleural Mesothelioma Cell Lines for Kinase Activity May Identify New Mechanisms of Therapy Resistance in Patients Receiving Platin-Based Chemotherapy. 2019 2
31 29071589 Melatonin increases human cervical cancer HeLa cells apoptosis induced by cisplatin via inhibition of JNK/Parkin/mitophagy axis. 2018 Jan 1
32 29103194 Astragalus polysaccharides increase the sensitivity of SKOV3 cells to cisplatin. 2018 Feb 1
33 29393335 Schizandrin B inhibits the cis‑DDP‑induced apoptosis of HK‑2 cells by activating ERK/NF‑κB signaling to regulate the expression of survivin. 2018 Apr 2
34 29432736 miR-223/Hsp70/JNK/JUN/miR-223 feedback loop modulates the chemoresistance of osteosarcoma to cisplatin. 2018 Mar 11 2
35 29458150 PINK1 Protects Auditory Hair Cells and Spiral Ganglion Neurons from Cisplatin-induced Ototoxicity via Inducing Autophagy and Inhibiting JNK Signaling Pathway. 2018 May 20 1
36 29512740 Programmed cell death 4 overexpression enhances sensitivity to cisplatin via the JNK/c-Jun signaling pathway in bladder cancer. 2018 May 2
37 29940575 Knockdown of MiR-20a Enhances Sensitivity of Colorectal Cancer Cells to Cisplatin by Increasing ASK1 Expression. 2018 2
38 30032449 Repression of GRIM19 expression potentiates cisplatin chemoresistance in advanced bladder cancer cells via disrupting ubiquitination-mediated Bcl-xL degradation. 2018 Oct 1
39 28232663 cAMP signaling increases histone deacetylase 8 expression via the Epac2-Rap1A-Akt pathway in H1299 lung cancer cells. 2017 Feb 24 1
40 28287190 NLRX1 accelerates cisplatin-induced ototoxity in HEI-OC1 cells via promoting generation of ROS and activation of JNK signaling pathway. 2017 Mar 13 3
41 28597042 Cisplatin induces expression of drug resistance-related genes through c-jun N-terminal kinase pathway in human lung cancer cells. 2017 Aug 3
42 28598976 The dynamic role of autophagy and MAPK signaling in determining cell fate under cisplatin stress in osteosarcoma cells. 2017 1
43 28650468 MKP-1 suppresses PARP-1 degradation to mediate cisplatin resistance. 2017 Oct 26 1
44 28886730 Annexin A2 contributes to cisplatin resistance by activation of JNK-p53 pathway in non-small cell lung cancer cells. 2017 Sep 8 2
45 29033791 Protein Synthesis Inhibition and Activation of the c-Jun N-Terminal Kinase Are Potential Contributors to Cisplatin Ototoxicity. 2017 3
46 29039558 Insulin in combination with cisplatin induces the apoptosis of ovarian cancer cells via p53 and JNK activation. 2017 Dec 1
47 26534836 Time-staggered inhibition of JNK effectively sensitizes chemoresistant ovarian cancer cells to cisplatin and paclitaxel. 2016 Jan 4
48 27193727 Fenofibrate reduces cisplatin-induced apoptosis of renal proximal tubular cells via inhibition of JNK and p38 pathways. 2016 5
49 27313779 P53 Is Involved in a Three-Dimensional Architecture-Mediated Decrease in Chemosensitivity in Colon Cancer. 2016 3
50 27374471 C-Jun N-terminal kinase signalling pathway in response to cisplatin. 2016 Nov 4