| 1 |
32039671 | Recent Advances in c-Jun N-Terminal Kinase (JNK) Inhibitors. | 2021 |
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33710509 | JNK signaling as a target for anticancer therapy. | 2021 Apr |
2 |
| 3 |
31994958 | Selective inhibitors for JNK signalling: a potential targeted therapy in cancer. | 2020 Dec |
2 |
| 4 |
31105818 | Use of Saikosaponin D and JNK inhibitor SP600125, alone or in combination, inhibits malignant properties of human osteosarcoma U2 cells. | 2019 |
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31731779 | Penta-1,2,3,4,6-O-Galloyl-β-D-Glucose Inhibits UVB-Induced Photoaging by Targeting PAK1 and JNK1. | 2019 Nov 15 |
1 |
| 6 |
32655976 | Mitochondrial Damage and Biogenesis in Acetaminophen-induced Liver Injury. | 2019 Dec |
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| 7 |
29128906 | Toll-Like Receptor-3 Mediates HIV-1-Induced Interleukin-6 Expression in the Human Brain Endothelium via TAK1 and JNK Pathways: Implications for Viral Neuropathogenesis. | 2018 Jul |
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29683976 | Activating P2X7 Receptors Increases Proliferation of Human Pancreatic Cancer Cells via ERK1/2 and JNK. | 2018 May/Jun |
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| 9 |
29945964 | Enhanced Glycolysis Supports Cell Survival in EGFR-Mutant Lung Adenocarcinoma by Inhibiting Autophagy-Mediated EGFR Degradation. | 2018 Aug 15 |
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| 10 |
30076967 | Inhibition of cytokine-mediated JNK signalling by purinergic P2Y11 receptors, a novel protective mechanism in endothelial cells. | 2018 Nov |
4 |
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30211540 | Allosteric Modulation of JNK Docking Site Interactions with ATP-Competitive Inhibitors. | 2018 Oct 9 |
5 |
| 12 |
27941886 | c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun. | 2017 May 4 |
4 |
| 13 |
28414098 | Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells. | 2017 Jul |
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| 14 |
28485044 | A Specific and Covalent JNK-1 Ligand Selected from an Encoded Self-Assembling Chemical Library. | 2017 Jun 16 |
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| 15 |
27013971 | KIF5C S176 Phosphorylation Regulates Microtubule Binding and Transport Efficiency in Mammalian Neurons. | 2016 |
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| 16 |
25485998 | Effects of hyperoxic exposure on signal transduction pathways in the lung. | 2015 Apr |
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| 17 |
25533502 | Butein suppresses ICAM-1 expression through the inhibition of IκBα and c-Jun phosphorylation in TNF-α- and PMA-treated HUVECs. | 2015 Feb |
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| 18 |
25711139 | Ischemia preconditioning protects astrocytes from ischemic injury through 14-3-3γ. | 2015 Oct |
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| 19 |
26307448 | Schisandrin B induces an Nrf2-mediated thioredoxin expression and suppresses the activation of inflammasome in vitro and in vivo. | 2015 Sep-Oct |
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| 20 |
24117156 | JNK signalling in cancer: in need of new, smarter therapeutic targets. | 2014 Jan |
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| 21 |
24407242 | JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death. | 2014 Jan 9 |
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| 22 |
24746749 | Inhibition of JNK and p38 MAPK phosphorylation by 5-(acetylamino)-4-oxo-6-phenyl-2-hexenoic acid methyl ester and 4-phenyl-butenoic acid decreases substance P-induced TNF-α upregulation in macrophages. | 2014 Jul |
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| 23 |
25043721 | Contribution of sodium channels to lamellipodial protrusion and Rac1 and ERK1/2 activation in ATP-stimulated microglia. | 2014 Dec |
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| 24 |
23410953 | Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds. | 2013 Jun |
1 |
| 25 |
23551430 | Luteolin suppresses UVB-induced photoageing by targeting JNK1 and p90 RSK2. | 2013 May |
1 |
| 26 |
22316156 | Computational insights for the discovery of non-ATP competitive inhibitors of MAP kinases. | 2012 |
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| 27 |
22351776 | Enzyme kinetics and interaction studies for human JNK1β1 and substrates activating transcription factor 2 (ATF2) and c-Jun N-terminal kinase (c-Jun). | 2012 Apr 13 |
2 |
| 28 |
22568706 | Designed ankyrin repeat proteins (DARPins) as novel isoform-specific intracellular inhibitors of c-Jun N-terminal kinases. | 2012 Aug 17 |
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| 29 |
22972801 | Pannexin1 contributes to pathophysiological ATP release in lipoapoptosis induced by saturated free fatty acids in liver cells. | 2012 Nov 15 |
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| 30 |
23002419 | From in Silico Discovery to intra-Cellular Activity: Targeting JNK-Protein Interactions with Small Molecules. | 2012 Aug 6 |
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| 31 |
19900593 | c-Jun N-terminal kinase (JNK) signaling: recent advances and challenges. | 2010 Mar |
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| 32 |
20477948 | P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways. | 2010 Aug |
4 |
| 33 |
20562007 | Signal transduction pathways associated with ATP-induced proliferation of colon adenocarcinoma cells. | 2010 Sep |
4 |
| 34 |
19059405 | SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression. | 2009 Jan 5 |
2 |
| 35 |
19836435 | Extracellular ATP activates MAP kinase cascades through a P2Y purinergic receptor in the human intestinal Caco-2 cell line. | 2009 Dec |
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| 36 |
18480747 | Induction of proapoptotic Daxx following ischemic acute kidney injury. | 2008 Aug |
2 |
| 37 |
17720133 | ATP modulation of mitogen activated protein kinases and intracellular Ca2+ in breast cancer (MCF-7) cells. | 2007 Oct 1 |
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| 38 |
16361361 | ATP stimulates MMP-2 release from human aortic smooth muscle cells via JNK signaling pathway. | 2006 May |
4 |
| 39 |
16418299 | Role of ATP in DNA synthesis of renal proximal tubule cells: involvement of calcium, MAPKs, and CDKs. | 2006 Jul |
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| 40 |
16923120 | Growth suppression of human mast cells expressing constitutively active c-kit receptors by JNK inhibitor SP600125. | 2006 Sep |
2 |
| 41 |
17092917 | Homogeneous and nonradioactive high-throughput screening platform for the characterization of kinase inhibitors in cell lysates. | 2006 Dec |
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| 42 |
15626722 | Inhibition of tumor growth, angiogenesis, and tumor cell proliferation by a small molecule inhibitor of c-Jun N-terminal kinase. | 2005 Apr |
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| 43 |
15882611 | Therapeutic promise of JNK ATP-noncompetitive inhibitors. | 2005 May |
2 |
| 44 |
15907786 | Substituting c-Jun N-terminal kinase-3 (JNK3) ATP-binding site amino acid residues with their p38 counterparts affects binding of JNK- and p38-selective inhibitors. | 2005 Jun 15 |
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| 45 |
15950471 | Structure-driven HtL: design and synthesis of novel aminoindazole inhibitors of c-Jun N-terminal kinase activity. | 2005 Jul 15 |
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| 46 |
14715932 | Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia. | 2004 Jan 7 |
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| 47 |
14767992 | Extracellular ATP activates c-jun N-terminal kinase signaling and cell cycle progression in hepatocytes. | 2004 Feb |
5 |
| 48 |
15113050 | Erianin induces a JNK/SAPK-dependent metabolic inhibition in human umbilical vein endothelial cells. | 2004 Mar-Apr |
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| 49 |
15141161 | Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125. | 2004 Jun 2 |
5 |
| 50 |
11259409 | Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue. | 2001 May 25 |
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