Tyrosine

mitogen-activated protein kinase 8 ; Homo sapiens







71 Article(s)
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1 29052270 Crystal structure of the human dual specificity phosphatase 1 catalytic domain. 2018 Feb 1
2 26705936 Tumor associated macrophages provide the survival resistance of tumor cells to hypoxic microenvironmental condition through IL-6 receptor-mediated signals. 2017 Jan 1
3 28011403 Cyanidin-3-O-glucoside ameliorates palmitate-induced insulin resistance by modulating IRS-1 phosphorylation and release of endothelial derived vasoactive factors. 2017 Mar 1
4 25708150 OGD induced modification of FAK- and PYK2-coupled pathways in organotypic hippocampal slice cultures. 2015 May 5 3
5 26429914 Phosphorylation of Glutathione S-Transferase P1 (GSTP1) by Epidermal Growth Factor Receptor (EGFR) Promotes Formation of the GSTP1-c-Jun N-terminal kinase (JNK) Complex and Suppresses JNK Downstream Signaling and Apoptosis in Brain Tumor Cells. 2015 Dec 25 6
6 22833523 Cigarette smoke disrupts the integrity of airway adherens junctions through the aberrant interaction of p120-catenin with the cytoplasmic tail of MUC1. 2013 Jan 1
7 24002526 Receptor-like protein tyrosine phosphatase κ negatively regulates the apoptosis of prostate cancer cells via the JNK pathway. 2013 Nov 2
8 21660049 A critical step for JNK activation: isomerization by the prolyl isomerase Pin1. 2012 Jan 2
9 22006247 Endoplasmic reticulum stress does not mediate palmitate-induced insulin resistance in mouse and human muscle cells. 2012 Jan 1
10 22433870 Tyrosine-phosphorylated caveolin-1 (Tyr-14) increases sensitivity to paclitaxel by inhibiting BCL2 and BCLxL proteins via c-Jun N-terminal kinase (JNK). 2012 May 18 4
11 23185569 Protein tyrosine phosphatase µ (PTP µ or PTPRM), a negative regulator of proliferation and invasion of breast cancer cells, is associated with disease prognosis. 2012 1
12 21737448 CaV1.3 channels and intracellular calcium mediate osmotic stress-induced N-terminal c-Jun kinase activation and disruption of tight junctions in Caco-2 CELL MONOLAYERS. 2011 Aug 26 1
13 22161830 c-Jun N-terminal kinase activity supports multiple phases of 3D-mammary epithelial acinus formation. 2011 1
14 20156194 Filamin associates with stress signalling kinases MKK7 and MKK4 and regulates JNK activation. 2010 Mar 29 3
15 20649571 2-Phenyl-5-(pyrrolidin-1-yl)-1-(3,4,5-trimethoxybenzyl)-1H-benzimidazole, a benzimidazole derivative, inhibits growth of human prostate cancer cells by affecting tubulin and c-Jun N-terminal kinase. 2010 Aug 1
16 17654528 c-jun-NH2JNK mediates invasive potential and EGFR activation by regulating the expression of HB-EGF in a urokinase-stimulated pathway. 2008 Feb 15 1
17 18460189 Diesel exhaust increases EGFR and phosphorylated C-terminal Tyr 1173 in the bronchial epithelium. 2008 May 6 1
18 18713649 JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin. 2008 Nov 8
19 17239858 Critical role of PTEN in the coupling between PI3K/Akt and JNK1/2 signaling in ischemic brain injury. 2007 Feb 6 1
20 17242197 Src family kinases directly regulate JIP1 module dynamics and activation. 2007 Apr 1
21 17392283 Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance. 2007 Jun 1 1
22 17488712 Distinct sensor pathways in the hierarchical control of SNAT2, a putative amino acid transceptor, by amino acid availability. 2007 Jul 6 1
23 17637928 Acquisition of apoptotic resistance in cadmium-transformed human prostate epithelial cells: Bcl-2 overexpression blocks the activation of JNK signal transduction pathway. 2007 Jul 1
24 17827708 Role of phosphatidylinositol 3-kinase activation on insulin action and its alteration in diabetic conditions. 2007 Sep 1
25 17848570 Role of MAPK phosphatase-1 in sustained activation of JNK during ethanol-induced apoptosis in hepatocyte-like VL-17A cells. 2007 Nov 2 1
26 17875416 Hyperosmotic activation of the CD95 system. 2007 1
27 15935618 Oncostatin M-induced activation of stress-activated MAP kinases depends on tyrosine 861 in the OSM receptor and requires Jak1 but not Src kinases. 2006 Jan 2
28 16150868 Interleukin-1alpha inhibits insulin signaling with phosphorylating insulin receptor substrate-1 on serine residues in 3T3-L1 adipocytes. 2006 Jan 1
29 16442502 Cloning and expression of human mitogen-activated protein kinase kinase 7gamma1. 2006 Mar 17 2
30 16734756 Hyperosmotic activation of the CD95 death receptor system. 2006 May-Jun 1
31 16099885 Mechanism and effect of thrombospondin-4 polymorphisms on neutrophil function. 2005 Dec 1 2
32 16123438 Establishment of effective methods for transducing genes into iris pigment epithelial cells by using adeno-associated virus type 2. 2005 Sep 1
33 16153436 Direct phosphorylation of proliferative and survival pathway proteins by RET. 2005 Aug 2
34 16186332 Mitomycin-C induces the apoptosis of human Tenon's capsule fibroblast by activation of c-Jun N-terminal kinase 1 and caspase-3 protease. 2005 Oct 1
35 14607833 Structural basis for the specific recognition of RET by the Dok1 phosphotyrosine binding domain. 2004 Feb 6 4
36 15001544 Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells. 2004 Jun 1
37 15271995 Reverse two-hybrid screening identifies residues of JNK required for interaction with the kinase interaction motif of JNK-interacting protein-1. 2004 Oct 8 1
38 12514174 JNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosis. 2003 Mar 14 1
39 12554784 Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes. 2003 Mar 1
40 12624093 Different properties of SEK1 and MKK7 in dual phosphorylation of stress-induced activated protein kinase SAPK/JNK in embryonic stem cells. 2003 May 9 6
41 12755958 Cell signalling and gene expression mediated by RET tyrosine kinase. 2003 Jun 1
42 12758252 Detection of JNK and p38 activation by flow cytometry analysis. 2003 Jun 15 1
43 11971192 Dual-specificity protein tyrosine phosphatase VHR down-regulates c-Jun N-terminal kinase (JNK). 2002 Apr 11 2
44 12087092 Role of Dok1 in cell signaling mediated by RET tyrosine kinase. 2002 Sep 6 1
45 12119061 A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signaling. 2002 Jul 15 1
46 11278622 MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression. 2001 May 4 1
47 11418587 Impaired synergistic activation of stress-activated protein kinase SAPK/JNK in mouse embryonic stem cells lacking SEK1/MKK4: different contribution of SEK2/MKK7 isoforms to the synergistic activation. 2001 Aug 17 3
48 10602026 TCR antagonist peptides induce formation of APC-T cell conjugates and activate a Rac signaling pathway. 2000 Jan 1
49 10849438 Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription. 2000 Jun 16 1
50 9891090 The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases. 1999 Feb 1