arsenite

mitogen-activated protein kinase 8 ; Homo sapiens







36 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34861471 Arsenite-induced cytotoxicity is regulated by p38-SQSTM1/p62 and JNK-BNIP3L/Nix signaling in lung cancer cells. 2022 Jan 8 1
2 32765280 JNK and Autophagy Independently Contributed to Cytotoxicity of Arsenite combined With Tetrandrine via Modulating Cell Cycle Progression in Human Breast Cancer Cells. 2020 1
3 30713663 Arsenite-induced apoptosis can be attenuated via depletion of mTOR activity to restore autophagy. 2019 Jan 1 1
4 26291278 Coordinated regulation of Nrf2 and histone H3 serine 10 phosphorylation in arsenite-activated transcription of the human heme oxygenase-1 gene. 2015 Oct 3
5 24184208 Intracellular mobility and nuclear trafficking of the stress-activated kinase JNK1 are impeded by hyperosmotic stress. 2014 Feb 2
6 25237887 Arsenite-activated JNK signaling enhances CPEB4-Vinexin interaction to facilitate stress granule assembly and cell survival. 2014 1
7 23194660 The accumulations of HIF-1α and HIF-2α by JNK and ERK are involved in biphasic effects induced by different levels of arsenite in human bronchial epithelial cells. 2013 Jan 15 7
8 23219847 Induction of apoptotic death and retardation of neuronal differentiation of human neural stem cells by sodium arsenite treatment. 2013 Apr 1 1
9 23376440 Sodium arsenite induces cyclooxygenase-2 expression in human uroepithelial cells through MAPK pathway activation and reactive oxygen species induction. 2013 Apr 1
10 23469214 Feedback regulations of miR-21 and MAPKs via Pdcd4 and Spry1 are involved in arsenite-induced cell malignant transformation. 2013 3
11 23715767 Increased expression of p21Waf1/Cip1 and JNK with costimulation of prostate cancer cell activation by an siRNA Egr-1 inhibitor. 2013 Aug 1
12 23968725 Arsenic induces the expressions of angiogenesis-related factors through PI3K and MAPK pathways in SV-HUC-1 human uroepithelial cells. 2013 Oct 9 2
13 22100391 Phosphorylation of the M3/6 dual-specificity phosphatase enhances the activation of JNK by arsenite. 2012 Mar 3
14 22366412 DNA-PKcs-mediated stabilization of p53 by JNK2 is involved in arsenite-induced DNA damage and apoptosis in human embryo lung fibroblast cells. 2012 May 5 1
15 21726611 Up-regulation of cyclin D1 by JNK1/c-Jun is involved in tumorigenesis of human embryo lung fibroblast cells induced by a low concentration of arsenite. 2011 Oct 10 4
16 19910486 A novel c-Jun N-terminal kinase (JNK)-binding protein WDR62 is recruited to stress granules and mediates a nonclassical JNK activation. 2010 Jan 1 1
17 19519318 PI3K/Akt/JNK/c-Jun signaling pathway is a mediator for arsenite-induced cyclin D1 expression and cell growth in human bronchial epithelial cells. 2009 Jun 2
18 19808956 Tpl2 is a key mediator of arsenite-induced signal transduction. 2009 Oct 15 6
19 18201741 The contribution of c-Jun N-terminal kinase activation and subsequent Bcl-2 phosphorylation to apoptosis induction in human B-cells is dependent on the mode of action of specific stresses. 2008 Apr 1 2
20 17289100 Biphasic effect of arsenite on cell proliferation and apoptosis is associated with the activation of JNK and ERK1/2 in human embryo lung fibroblast cells. 2007 Apr 1 6
21 17116751 IKKbeta programs to turn on the GADD45alpha-MKK4-JNK apoptotic cascade specifically via p50 NF-kappaB in arsenite response. 2006 Nov 20 3
22 15734884 EGF receptor-dependent JNK activation is involved in arsenite-induced p21Cip1/Waf1 upregulation and endothelial apoptosis. 2005 Jul 2
23 14514659 Opposed arsenite-induced signaling pathways promote cell proliferation or apoptosis in cultured lung cells. 2004 Jan 8
24 14967008 The protective role of intracellular GSH status in the arsenite-induced vascular endothelial dysfunction. 2004 Feb 2
25 15028728 Arsenite sensitizes human melanomas to apoptosis via tumor necrosis factor alpha-mediated pathway. 2004 May 21 1
26 12946653 The protective role of NF-kappaB and AP-1 in arsenite-induced apoptosis in aortic endothelial cells. 2003 Sep 1 1
27 11948422 Differential effects of stress stimuli on a JNK-inactivating phosphatase. 2002 Apr 4 1
28 11983707 The p38 and JNK pathways cooperate to trans-activate vitamin D receptor via c-Jun/AP-1 and sensitize human breast cancer cells to vitamin D(3)-induced growth inhibition. 2002 Jul 19 1
29 12075113 Differential activation of the c-Jun N-terminal kinase pathway in arsenite-induced apoptosis and sensitization of chemically resistant compared to susceptible B-lymphoma cell lines. 2002 Jul 2
30 12426127 The molecular mechanisms of arsenic-induced cell transformation and apoptosis. 2002 Oct 2
31 11429707 Contrasting roles of NF-kappaB and JNK in arsenite-induced p53-independent expression of GADD45alpha. 2001 Jun 14 3
32 10964950 Arsenite-induced apoptosis in cortical neurons is mediated by c-Jun N-terminal protein kinase 3 and p38 mitogen-activated protein kinase. 2000 Sep 1 2
33 11055208 Molecular aspects of arsenic stress. 2000 Oct-Dec 3
34 10082520 Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: a novel pathway controlled by HSP72. 1999 Apr 1
35 10329651 Requirement of Erk, but not JNK, for arsenite-induced cell transformation. 1999 May 21 3
36 10618720 Signal transduction pathways regulated by arsenate and arsenite. 1999 Dec 16 7