Melatonin

mitogen-activated protein kinase 8 ; Homo sapiens







41 Article(s)
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1 33763168 Melatonin Attenuates ox-LDL-Induced Endothelial Dysfunction by Reducing ER Stress and Inhibiting JNK/Mff Signaling. 2021 3
2 34074034 Melatonin Induces Apoptosis and Modulates Cyclin Expression and MAPK Phosphorylation in Pancreatic Stellate Cells Subjected to Hypoxia. 2021 May 24 1
3 34343226 Melatonin regulates proliferation and apoptosis of endometrial stromal cells via MT1. 2021 Oct 12 2
4 31959998 Melatonin triggers the anticancer potential of phenylarsine oxide via induction of apoptosis through ROS generation and JNK activation. 2020 Mar 1 1
5 31982774 Effects of miR-34b/miR-892a Upregulation and Inhibition of ABCB1/ABCB4 on Melatonin-Induced Apoptosis in VCR-Resistant Oral Cancer Cells. 2020 Mar 6 2
6 32918860 Melatonin as a potential inhibitor of kidney cancer: A survey of the molecular processes. 2020 Nov 1
7 32973495 A Potent Antioxidant Endogenous Neurohormone Melatonin, Rescued MCAO by Attenuating Oxidative Stress-Associated Neuroinflammation. 2020 1
8 31081481 Melatonin attenuates expression of cyclooxygenase-2 (COX-2) in activated microglia induced by lipopolysaccharide (LPS). 2019 1
9 31579126 Different Effects of Melatonin on X-Rays-Irradiated Cancer Cells in a Dose-Dependent Manner. 2019 Jul-Sep 4
10 32063713 The Therapeutic Effect of Melatonin on GC by Inducing Cell Apoptosis and Autophagy Induced by Endoplasmic Reticulum Stress. 2019 1
11 29071589 Melatonin increases human cervical cancer HeLa cells apoptosis induced by cisplatin via inhibition of JNK/Parkin/mitophagy axis. 2018 Jan 4
12 29207036 Periostin has a protective role in melatonin‑induced cell apoptosis by inhibiting the eIF2α‑ATF4 pathway in human osteoblasts. 2018 Feb 1
13 29363570 Melatonin reduces oxidative damage in mouse granulosa cells via restraining JNK-dependent autophagy. 2018 Mar 5
14 29766567 Melatonin attenuates osteosarcoma cell invasion by suppression of C-C motif chemokine ligand 24 through inhibition of the c-Jun N-terminal kinase pathway. 2018 Oct 7
15 28178378 Melatonin promotes sorafenib-induced apoptosis through synergistic activation of JNK/c-jun pathway in human hepatocellular carcinoma. 2017 Apr 3
16 28387244 The apoptotic mechanisms of MT-6, a mitotic arrest inducer, in human ovarian cancer cells. 2017 Apr 7 2
17 28454460 Melatonin treatment induces apoptosis through regulating the nuclear factor-κB and mitogen-activated protein kinase signaling pathways in human gastric cancer SGC7901 cells. 2017 Apr 2
18 28912098 Melatonin-mediated upregulation of Sirt3 attenuates sodium fluoride-induced hepatotoxicity by activating the MT1-PI3K/AKT-PGC-1α signaling pathway. 2017 Nov 1
19 26607805 Melatonin enhances arsenic trioxide-induced cell death via sustained upregulation of Redd1 expression in breast cancer cells. 2016 Feb 15 2
20 26639427 Targeting different pathophysiological events after traumatic brain injury in mice: Role of melatonin and memantine. 2016 Jan 26 1
21 26732239 Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB DNA-binding activity. 2016 Apr 1
22 27271323 Melatonin Inhibits CXCL10 and MMP-1 Production in IL-1β-Stimulated Human Periodontal Ligament Cells. 2016 Aug 2
23 27666165 Melatonin induces cell apoptosis in Mia PaCa-2 cells via the suppression of nuclear factor-κB and activation of ERK and JNK: A novel therapeutic implication for pancreatic cancer. 2016 Nov 1
24 27832629 Inhibition of ERK1/2 Signaling Pathway is Involved in Melatonin's Antiproliferative Effect on Human MG-63 Osteosarcoma Cells. 2016 1
25 25975536 Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells. 2015 Sep 1
26 26645893 Melatonin Induces Cell Apoptosis in AGS Cells Through the Activation of JNK and P38 MAPK and the Suppression of Nuclear Factor-Kappa B: a Novel Therapeutic Implication for Gastric Cancer. 2015 6
27 24720799 Melatonin inhibits MUC5AC production via suppression of MAPK signaling in human airway epithelial cells. 2014 May 1
28 24992189 Melatonin inhibits the migration of human lung adenocarcinoma A549 cell lines involving JNK/MAPK pathway. 2014 3
29 25033992 A review of melatonin in hepatic ischemia/reperfusion injury and clinical liver disease. 2014 Nov 2
30 24008433 2-Aminophenoxazine-3-one-induced apoptosis via generation of reactive oxygen species followed by c-jun N-terminal kinase activation in the human glioblastoma cell line LN229. 2013 Nov 1
31 21988060 Prevention of ERK activation involves melatonin-induced G(1) and G(2) /M phase arrest in the human osteoblastic cell line hFOB 1.19. 2012 Aug 1
32 22348531 Melatonin suppresses proinflammatory mediators in lipopolysaccharide-stimulated CRL1999 cells via targeting MAPK, NF-κB, c/EBPβ, and p300 signaling. 2012 Sep 1
33 22507555 Cytoprotective and anti-inflammatory effects of melatonin in hydrogen peroxide-stimulated CHON-001 human chondrocyte cell line and rabbit model of osteoarthritis via the SIRT1 pathway. 2012 Oct 1
34 20964705 Melatonin attenuates apoptotic liver damage in fulminant hepatic failure induced by the rabbit hemorrhagic disease virus. 2011 Jan 2
35 21718361 Melatonin modulation of intracellular signaling pathways in hepatocarcinoma HepG2 cell line: role of the MT1 receptor. 2011 Nov 1
36 20082663 The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin receptors. 2010 Mar 1
37 20738755 The mechanism for the neuroprotective effect of melatonin against methamphetamine-induced autophagy. 2010 Nov 1
38 21311676 Melatonin Induces Apoptotic Cell Death via p53 in LNCaP Cells. 2010 Dec 2
39 18930812 ERK MAPK activation mediates the antiapoptotic signaling of melatonin in UVB-stressed U937 cells. 2009 Feb 1 1
40 19522739 Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer. 2009 Aug 6
41 19012662 Melatonin induces cell cycle arrest and apoptosis in hepatocarcinoma HepG2 cell line. 2008 Nov 1