Reactive Oxygen Species

mitogen-activated protein kinase 8 ; Homo sapiens







484 Article(s)
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401 18305405 Low energy proton beam induces tumor cell apoptosis through reactive oxygen species and activation of caspases. 2008 Feb 29 3
402 18324519 Involvement of ROS/ASMase/JNK signalling pathway in inhibiting UVA-induced apoptosis of HaCaT cells by polypeptide from Chlamys farreri. 2008 Jan 1
403 18374381 Involvement of reactive oxygen species/c-Jun NH(2)-terminal kinase pathway in kotomolide A induces apoptosis in human breast cancer cells. 2008 Jun 1 1
404 18398104 Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation. 2008 Apr 16 5
405 18403484 Dexamethasone-induced expression of endothelial mitogen-activated protein kinase phosphatase-1 involves activation of the transcription factors activator protein-1 and 3',5'-cyclic adenosine 5'-monophosphate response element-binding protein and the generation of reactive oxygen species. 2008 Jul 1
406 18412143 The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells. 2008 Oct 1
407 18566239 Arsenic trioxide decreases AKT protein in a caspase-dependent manner. 2008 Jun 1
408 18569013 Chromium (VI) induces insulin resistance in 3T3-L1 adipocytes through elevated reactive oxygen species generation. 2008 Jun 1
409 18569016 Chronic insulin treatment causes insulin resistance in 3T3-L1 adipocytes through oxidative stress. 2008 Jun 1
410 18606492 The novel isoflavone 7-hydroxy-3',4'-benzoisoflavone induces cell apoptosis in human osteosarcoma cells. 2008 Nov 18 1
411 18618576 Novel 2-step synthetic indole compound 1,1,3-tri(3-indolyl)cyclohexane inhibits cancer cell growth in lung cancer cells and xenograft models. 2008 Aug 15 3
412 18663379 Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells. 2008 Aug 1
413 18691550 Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis. 2008 Aug 12 1
414 18692129 Superoxide dismutase attenuates hyperoxia-induced interleukin-8 induction via AP-1. 2008 Oct 15 1
415 18703135 Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5. 2008 Oct 1 2
416 18728404 The JNK signaling pathway is involved in sodium-selenite-induced apoptosis mediated by reactive oxygen in HepG2 cells. 2008 May 2
417 18840412 Glibenclamide exerts an antitumor activity through reactive oxygen species-c-jun NH2-terminal kinase pathway in human gastric cancer cell line MGC-803. 2008 Dec 15 2
418 18923045 Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand. 2008 Oct 15 1
419 16963249 Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage. 2007 May 1
420 17121845 Sustained JNK activation in response to tumor necrosis factor is mediated by caspases in a cell type-specific manner. 2007 Jan 26 1
421 17296806 A critical role of luteolin-induced reactive oxygen species in blockage of tumor necrosis factor-activated nuclear factor-kappaB pathway and sensitization of apoptosis in lung cancer cells. 2007 May 3
422 17308059 17-Allylamino-17-demethoxygeldanamycin enhances the lethality of deoxycholic acid in primary rodent hepatocytes and established cell lines. 2007 Feb 2
423 17360708 Cyanidin-3-rutinoside, a natural polyphenol antioxidant, selectively kills leukemic cells by induction of oxidative stress. 2007 May 4 2
424 17390063 Ionizing radiation-induced micronucleus formation is mediated by reactive oxygen species that are produced in a manner dependent on mitochondria, Nox1, and JNK. 2007 May 2
425 17400550 Hypoxia-inducible factor-1alpha, a key factor in the keratinocyte response to UVB exposure. 2007 Jun 1 1
426 17576159 Lipid rafts and oxidative stress-induced cell death. 2007 Sep 1
427 17603935 Tumor necrosis factor-alpha-induced reactive oxygen species formation is mediated by JNK1-dependent ferritin degradation and elevation of labile iron pool. 2007 Jul 15 4
428 17647244 Garlic compounds generate reactive oxygen species leading to activation of stress kinases and cysteine proteases for apoptosis in human glioblastoma T98G and U87MG cells. 2007 Sep 1 1
429 17875416 Hyperosmotic activation of the CD95 system. 2007 2
430 17881465 ANG II induces c-Jun NH2-terminal kinase activation and proliferation of human mesangial cells via redox-sensitive transactivation of the EGFR. 2007 Dec 1
431 18481208 Differential role of reactive oxygen species in the activation of mitogen-activated protein kinases and Akt by key receptors on B-lymphocytes: CD40, the B cell antigen receptor, and CXCR4. 2007 Jun 5
432 16341124 Reactive oxygen species mediate crosstalk between NF-kappaB and JNK. 2006 May 4
433 16387755 Mitochondrial localization of catalase provides optimal protection from H2O2-induced cell death in lung epithelial cells. 2006 May 2
434 16407847 N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells. 2006 May 4 1
435 16412424 Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line (HuH-7) through the activation of JNK1/2 and the downregulation of Akt. 2006 Jan 23 1
436 16456579 The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease. 2006 May 3
437 16515547 Critical role of ASK1 in the 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells. 2006 Apr 3
438 16540388 JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species. 2006 Mar 15 4
439 16651444 3,3'-Diindolylmethane is a novel mitochondrial H(+)-ATP synthase inhibitor that can induce p21(Cip1/Waf1) expression by induction of oxidative stress in human breast cancer cells. 2006 May 1 1
440 16707465 c-Jun NH(2)-terminal kinase signaling axis regulates diallyl trisulfide-induced generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells. 2006 May 15 5
441 16734756 Hyperosmotic activation of the CD95 death receptor system. 2006 May-Jun 1
442 16787235 Signaling mechanisms underlying Abeta toxicity: potential therapeutic targets for Alzheimer's disease. 2006 Jun 3
443 16873882 TNF receptor superfamily-induced cell death: redox-dependent execution. 2006 Aug 1
444 16973888 Ginsenoside-Rh2-induced mitochondrial depolarization and apoptosis are associated with reactive oxygen species- and Ca2+-mediated c-Jun NH2-terminal kinase 1 activation in HeLa cells. 2006 Dec 5
445 17023263 Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes. 2006 Nov 1 2
446 17072325 Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance. 2006 Oct 30 3
447 17110930 An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway. 2006 Nov 29 4
448 15592360 Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation. 2005 Jan 1
449 15701637 Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation. 2005 Apr 15 1
450 15705601 Epigallocatechin-3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells. 2005 May 1