Reactive Oxygen Species

mitogen-activated protein kinase 8 ; Homo sapiens







484 Article(s)
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351 20144638 Involvement of p38 MAPK- and JNK-modulated expression of Bcl-2 and Bax in Naja nigricollis CMS-9-induced apoptosis of human leukemia K562 cells. 2010 Jun 15 1
352 20185286 Allicin protects against cardiac hypertrophy and fibrosis via attenuating reactive oxygen species-dependent signaling pathways. 2010 Dec 1
353 20227042 Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation. 2010 Mar 16 1
354 20230822 Hepatitis C virus regulates transforming growth factor beta1 production through the generation of reactive oxygen species in a nuclear factor kappaB-dependent manner. 2010 Jun 2
355 20381862 The effect of carboxydextran-coated superparamagnetic iron oxide nanoparticles on c-Jun N-terminal kinase-mediated apoptosis in human macrophages. 2010 Jul 2
356 20398386 Oxidative stress in NSC-741909-induced apoptosis of cancer cells. 2010 Apr 16 5
357 20435848 Resistin decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells. 2010 Jul 1
358 20438840 Enhanced cytotoxicity and activation of ROS-dependent c-Jun NH2-terminal kinase and caspase-3 by low doses of tetrandrine-loaded nanoparticles in Lovo cells--a possible Trojan strategy against cancer. 2010 Aug 4
359 20446899 Protein tyrosine kinase pathway-derived ROS/NO productions contribute to G2/M cell cycle arrest in evodiamine-treated human cervix carcinoma HeLa cells. 2010 Jul 1
360 20534739 Induction of B-chronic lymphocytic leukemia cell apoptosis by arsenic trioxide involves suppression of the phosphoinositide 3-kinase/Akt survival pathway via c-jun-NH2 terminal kinase activation and PTEN upregulation. 2010 Sep 1 1
361 20580989 Reactive oxygen species-mitochondria pathway involved in LYG-202-induced apoptosis in human hepatocellular carcinoma HepG(2) cells. 2010 Oct 1 2
362 20590610 Activation of c-Jun N-terminal kinase is essential for mitochondrial membrane potential change and apoptosis induced by doxycycline in melanoma cells. 2010 Jul 2
363 20647313 The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways. 2010 Sep 24 2
364 20652490 Reactive oxygen species in TNFalpha-induced signaling and cell death. 2010 Jul 1
365 20696242 Different altered pattern expression of genes related to apoptosis in isolated methylmalonic aciduria cblB type and combined with homocystinuria cblC type. 2010 Nov 1
366 20727582 Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-kappaB pathways. 2010 Nov 1
367 20736062 SOD1 and MitoTEMPO partially prevent mitochondrial permeability transition pore opening, necrosis, and mitochondrial apoptosis after ATP depletion recovery. 2010 Nov 30 1
368 20840847 3,6-Dihydroxyflavone induces apoptosis in leukemia HL-60 cell via reactive oxygen species-mediated p38 MAPK/JNK pathway. 2010 Dec 1 1
369 20920557 Irciniastatin A induces JNK activation that is involved in caspase-8-dependent apoptosis via the mitochondrial pathway. 2010 Dec 15 1
370 20932751 CWJ-081, a novel 3-arylisoquinoline derivative, induces apoptosis in human leukemia HL-60 cells partially involves reactive oxygen species through c-Jun NH2-terminal kinase pathway. 2010 Nov 15 1
371 20974135 Inhibition of NF-κB induces a switch from CD95L-dependent to CD95L-independent and JNK-mediated apoptosis in T cells. 2010 Nov 19 2
372 21038848 Diallyl disulfide induces apoptosis in human leukemia HL-60 cells through activation of JNK mediated by reactive oxygen. 2010 Sep 2
373 21078900 Endoplasmic reticulum stress-mediated apoptosis of EBV-transformed B cells by cross-linking of CD70 is dependent upon generation of reactive oxygen species and activation of p38 MAPK and JNK pathway. 2010 Dec 15 1
374 21472273 The MEK inhibitor PD98059 attenuates growth inhibition and death in gallic acid-treated Calu-6 lung cancer cells by preventing glutathione depletion. 2010 May-Jun 1
375 24281075 The role of oxidative stress in carcinogenesis induced by metals and xenobiotics. 2010 Apr 8 1
376 18681908 SIRT1 confers protection against UVB- and H2O2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes. 2009 Sep 1
377 18805632 Nitric oxide-donating aspirin inhibits the growth of pancreatic cancer cells through redox-dependent signaling. 2009 Jan 18 1
378 19037093 AMP kinase signaling determines whether c-Jun N-terminal kinase promotes survival or apoptosis during glucose deprivation. 2009 Mar 1
379 19118896 Gabor Than Award Lecture 2008: pre-eclampsia - from placental oxidative stress to maternal endothelial dysfunction. 2009 Mar 1
380 19277946 The c-Jun N-terminal kinase mediates the induction of oxidative stress and insulin resistance by palmitate and toll-like receptor 2 and 4 ligands in 3T3-L1 adipocytes. 2009 Jul 1
381 19292871 Chronic high-dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway. 2009 Apr 7
382 19325135 PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation. 2009 May 1
383 19361274 Redox regulation of tumor necrosis factor signaling. 2009 Sep 1
384 19429257 Effects of polychlorinated biphenyls on the neutrophil NADPH oxidase system. 2009 Jun 22 1
385 19468286 An agonistic monoclonal antibody against DR5 induces ROS production, sustained JNK activation and Endo G release in Jurkat leukemia cells. 2009 Aug 3
386 19486916 Role of oxidative stress and JNK pathway in apoptotic death induced by potassium deprivation and staurosporine in cerebellar granule neurons. 2009 Dec 2
387 19549704 Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells. 2009 Oct 1
388 19574249 Reactive oxygen species-dependent activation of Bax and poly(ADP-ribose) polymerase-1 is required for mitochondrial cell death induced by triterpenoid pristimerin in human cervical cancer cells. 2009 Oct 3
389 19652370 Berberine protects mesenchymal stem cells against hypoxia-induced apoptosis in vitro. 2009 Aug 1
390 19673930 Erlotinib activates mitochondrial death pathways related to the production of reactive oxygen species in the human non-small cell lung cancer cell line A549. 2009 May 1
391 19751824 ROS inhibit the expression of testicular steroidogenic enzyme genes via the suppression of Nur77 transactivation. 2009 Dec 1 2
392 19801848 Costunolide-induced apoptosis in human leukemia cells: involvement of c-jun N-terminal kinase activation. 2009 Oct 3
393 19846917 The effect of MAPK inhibitors on arsenic trioxide-treated Calu-6 lung cells in relation to cell death, ROS and GSH levels. 2009 Oct 1
394 17939949 Toll-like receptor 9-stimulated monocyte chemoattractant protein-1 is mediated via JNK-cytosolic phospholipase A2-ROS signaling. 2008 Jan 1
395 18068334 Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2. 2008 Feb 1
396 18199537 Glioma pathogenesis-related protein 1 exerts tumor suppressor activities through proapoptotic reactive oxygen species-c-Jun-NH2 kinase signaling. 2008 Jan 15 3
397 18218673 TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species. 2008 Apr 2
398 18219313 NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production. 2008 Mar 1
399 18262755 Amplification of the gamma-irradiation-induced cell death pathway by reactive oxygen species in human U937 cells. 2008 May 7
400 18281123 A combination of sulindac and arsenic trioxide synergistically induces apoptosis in human lung cancer H1299 cells via c-Jun NH2-terminal kinase-dependent Bcl-xL phosphorylation. 2008 Sep 3