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mitogen-activated protein kinase 8 ; Homo sapiens







130 Article(s)
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101 23933736 Myc inhibition impairs autophagosome formation. 2013 Dec 20 1
102 23973637 Comparative analysis of ER stress response into HIV protease inhibitors: lopinavir but not darunavir induces potent ER stress response via ROS/JNK pathway. 2013 Dec 2
103 24386346 Ginsenoside Rg-1 protects retinal pigment epithelium (RPE) cells from cobalt chloride (CoCl2) and hypoxia assaults. 2013 2
104 21882190 High glucose-induced repression of RAR/RXR in cardiomyocytes is mediated through oxidative stress/JNK signaling. 2012 Jun 1
105 22285910 Vinca alkaloids cause aberrant ROS-mediated JNK activation, Mcl-1 downregulation, DNA damage, mitochondrial dysfunction, and apoptosis in lung adenocarcinoma cells. 2012 May 1 3
106 22288910 Cyclooxygenase-2 expression is up-regulated by 2-aminobiphenyl in a ROS and MAPK-dependent signaling pathway in a bladder cancer cell line. 2012 Mar 19 1
107 22472731 Activation of c-Jun NH(2)-terminal kinase is required for porcine reproductive and respiratory syndrome virus-induced apoptosis but not for virus replication. 2012 Jun 2
108 22881126 The tyrphostin AG1478 augments oridonin-induced A431 cell apoptosis by blockage of JNK MAPK and enhancement of oxidative stress. 2012 Nov 2
109 20940027 Codonopsis lanceolata extract induces G0/G1 arrest and apoptosis in human colon tumor HT-29 cells--involvement of ROS generation and polyamine depletion. 2011 Jan 2
110 21453688 Vitamin K3-2,3-epoxide induction of apoptosis with activation of ROS-dependent ERK and JNK protein phosphorylation in human glioma cells. 2011 Aug 15 1
111 21998736 β-lapachone significantly increases the effect of ionizing radiation to cause mitochondrial apoptosis via JNK activation in cancer cells. 2011 2
112 19700217 Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone-mediated apoptosis in human non-small cell lung cancer cells. 2010 Jun 1
113 19780038 Calcium-stimulated mitogen-activated protein kinase activation elicits Bcl-xL downregulation and Bak upregulation in notexin-treated human neuroblastoma SK-N-SH cells. 2010 Jan 1
114 20360613 Role of endothelin-1 receptor blockers on hemodynamic parameters and oxidative stress. 2010 Jan-Feb 1
115 20368806 Simultaneous induction of non-canonical autophagy and apoptosis in cancer cells by ROS-dependent ERK and JNK activation. 2010 Apr 2 2
116 18767140 Activation of JNK and PAK2 is essential for citrinin-induced apoptosis in a human osteoblast cell line. 2009 Aug 1
117 18695917 Role of p38 MAPK and JNK in enhanced cervical cancer cell killing by the combination of arsenic trioxide and ionizing radiation. 2008 Sep 1
118 18983820 Nuclear-factor-kappaB (NF-kappaB) and radical oxygen species play contrary roles in transforming growth factor-beta1 (TGF-beta1)-induced apoptosis in hepatocellular carcinoma (HCC) cells. 2008 Dec 26 3
119 17005604 Advanced glycation end products induce apoptosis in fibroblasts through activation of ROS, MAP kinases, and the FOXO1 transcription factor. 2007 Feb 1
120 17707342 Mixed lineage kinase 3 connects reactive oxygen species to c-Jun NH2-terminal kinase-induced mitochondrial apoptosis in genipin-treated PC3 human prostate cancer cells. 2007 Oct 19 2
121 15908180 Synergistic activation of JNK/SAPK induced by TNF-alpha and IFN-gamma: apoptosis of pancreatic beta-cells via the p53 and ROS pathway. 2005 Dec 5
122 15130759 Tetrandrine-induced apoptosis is mediated by activation of caspases and PKC-delta in U937 cells. 2004 May 15 1
123 15197348 MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells. 2004 Aug 1
124 15581626 NF-kappaB activation prevents apoptotic oxidative stress via an increase of both thioredoxin and MnSOD levels in TNFalpha-treated Ewing sarcoma cells. 2004 Dec 3 1
125 12599206 Characterization of apoptosis signal transduction pathways in HL-5 cardiomyocytes exposed to ischemia/reperfusion oxidative stress model. 2003 Apr 1
126 12663441 Oxidative stress is a critical mediator of the angiotensin II signal in human neutrophils: involvement of mitogen-activated protein kinase, calcineurin, and the transcription factor NF-kappaB. 2003 Jul 15 1
127 14614324 Induction of apoptosis in BCR/ABL+ cells by histone deacetylase inhibitors involves reciprocal effects on the RAF/MEK/ERK and JNK pathways. 2003 Sep-Oct 1
128 12151316 Proteasome inhibitors stimulate interleukin-8 expression via Ras and apoptosis signal-regulating kinase-dependent extracellular signal-related kinase and c-Jun N-terminal kinase activation. 2002 Aug 1
129 11360927 Pyrrolidine dithiocarbamate inhibits serum-induced NF-kappaB activation and induces apoptosis in ROS 17/2.8 osteoblasts. 2001 Feb 1
130 10531389 Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin. 1999 Nov 1