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mitogen-activated protein kinase 8 ; Homo sapiens







130 Article(s)
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51 27181592 JNK Activation Contributes to Oxidative Stress-Induced Parthanatos in Glioma Cells via Increase of Intracellular ROS Production. 2017 Jul 3
52 27899257 Juglanin induces apoptosis and autophagy in human breast cancer progression via ROS/JNK promotion. 2017 Jan 1
53 28103509 3',5-dihydroxy-3,4',7-trimethoxyflavone-induces ER-stress-associated HCT-116 programmed cell death via redox signaling. 2017 Apr 1
54 28488794 Apoptotic Activity of Lactobacillus plantarum DGK-17-Fermented Soybean Seed Extract in Human Colon Cancer Cells via ROS-JNK Signaling Pathway. 2017 Jun 1
55 28518151 Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2. 2017 May 18 2
56 28662515 TRAIL Enhances Shikonin Induced Apoptosis through ROS/JNK Signaling in Cholangiocarcinoma Cells. 2017 2
57 28712866 Cell-free methemoglobin drives platelets to apoptosis via mitochondrial ROS-mediated activation of JNK and p38 MAP kinase. 2017 Sep 9 1
58 29088756 trans-4,4'-Dihydroxystilbene (DHS) inhibits human neuroblastoma tumor growth and induces mitochondrial and lysosomal damages in neuroblastoma cell lines. 2017 Sep 26 1
59 29348836 Vitexin confers HSF-1 mediated autophagic cell death by activating JNK and ApoL1 in colorectal carcinoma cells. 2017 Dec 22 1
60 26086416 Selective killing of gastric cancer cells by a small molecule targeting ROS-mediated ER stress activation. 2016 Jun 1
61 26468015 ROS-mediated activation of JNK/p38 contributes partially to the pro-apoptotic effect of ajoene on cells of lung adenocarcinoma. 2016 Mar 2
62 26472167 PM2.5 induces embryonic growth retardation: Potential involvement of ROS-MAPKs-apoptosis and G0/G1 arrest pathways. 2016 Dec 1
63 26502273 The Molecular Influence of Graphene and Graphene Oxide on the Immune System Under In Vitro and In Vivo Conditions. 2016 Jun 1
64 26511233 Dexamethasone promotes hypertrophy of H9C2 cardiomyocytes through calcineurin B pathway, independent of NFAT activation. 2016 Jan 1
65 26707143 Curcumin enhances the antitumor effect of ABT-737 via activation of the ROS-ASK1-JNK pathway in hepatocellular carcinoma cells. 2016 Feb 1
66 26716417 Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. 2016 Feb 2 2
67 27108344 Apoptosis and autophagy induced by pyropheophorbide-α methyl ester-mediated photodynamic therapy in human osteosarcoma MG-63 cells. 2016 Jun 2
68 27392019 Correction: Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation. 2016 1
69 27563337 The Natural Occurring Compounds Targeting Endoplasmic Reticulum Stress. 2016 1
70 25529445 Eicosapentaenoic acid (EPA) induced apoptosis in HepG2 cells through ROS-Ca(2+)-JNK mitochondrial pathways. 2015 Jan 24 4
71 25611379 Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells: an in vitro and in vivo study. 2015 Jan 22 1
72 25615876 Pretreatment with pPolyHb attenuates H2O2-induced endothelial cell injury through inhibition of JNK/p38 MAPK pathway by upregulation of heme oxygenase-1. 2015 Jun 1
73 25791820 Synergistic anticancer potential of dichloroacetate and estradiol analogue exerting their effect via ROS-JNK-Bcl-2-mediated signalling pathways. 2015 2
74 25832424 C-reactive protein stimulates RAGE expression in human coronary artery endothelial cells in vitro via ROS generation and ERK/NF-κB activation. 2015 Apr 1
75 25909160 IL-32α suppresses colorectal cancer development via TNFR1-mediated death signaling. 2015 Apr 20 1
76 26001727 c-Jun N-terminal kinase attenuates TNFα signaling by reducing Nox1-dependent endosomal ROS production in vascular smooth muscle cells. 2015 Sep 2
77 26002468 Palmitate promotes autophagy and apoptosis through ROS-dependent JNK and p38 MAPK. 2015 Jul 31 2
78 26086160 Reactive oxygen species mediate nitric oxide production through ERK/JNK MAPK signaling in HAPI microglia after PFOS exposure. 2015 Oct 15 1
79 26089952 Polypeptide Fraction from Arca subcrenata Induces Apoptosis and G2/M Phase Arrest in HeLa Cells via ROS-Mediated MAPKs Pathways. 2015 1
80 26180584 Protocatechuic Acid Prevents oxLDL-Induced Apoptosis by Activating JNK/Nrf2 Survival Signals in Macrophages. 2015 1
81 26203587 Tanshinone IIA Facilitates TRAIL Sensitization by Up-regulating DR5 through the ROS-JNK-CHOP Signaling Axis in Human Ovarian Carcinoma Cell Lines. 2015 Aug 17 2
82 26235743 New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway. 2015 Sep 2
83 26642060 bFGF-Regulating MAPKs Are Involved in High Glucose-Mediated ROS Production and Delay of Vascular Endothelial Cell Migration. 2015 1
84 24122234 Amsacrine suppresses matrix metalloproteinase-2 (MMP-2)/MMP-9 expression in human leukemia cells. 2014 May 1
85 24366007 Nutlin-3 induces HO-1 expression by activating JNK in a transcription-independent manner of p53. 2014 Mar 2
86 24465942 Targeting cancer cells with reactive oxygen and nitrogen species generated by atmospheric-pressure air plasma. 2014 4
87 24812029 Induction of ROS-independent JNK-activation-mediated apoptosis by a novel coumarin-derivative, DMAC, in human colon cancer cells. 2014 Jul 25 1
88 24915933 Disulfiram targeting lymphoid malignant cell lines via ROS-JNK activation as well as Nrf2 and NF-kB pathway inhibition. 2014 Jun 11 2
89 25044446 Oxidized HDL induces cytotoxic effects: implications for atherogenic mechanism. 2014 Nov 1
90 25064608 Induction of hepatoma carcinoma cell apoptosis through activation of the JNK-nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-ROS self-driven death signal circuit. 2014 Oct 28 8
91 25175743 c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells. 2014 Aug 30 2
92 25305377 Abrus precatorius agglutinin-derived peptides induce ROS-dependent mitochondrial apoptosis through JNK and Akt/P38/P53 pathways in HeLa cells. 2014 Oct 5 3
93 25321472 Medicarpin, a legume phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis through the induction of DR5 and activation of the ROS-JNK-CHOP pathway. 2014 Oct 16 2
94 25341038 JNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stress. 2014 Oct 23 2
95 22627996 Xanthorrhizol induces apoptosis through ROS-mediated MAPK activation in human oral squamous cell carcinoma cells and inhibits DMBA-induced oral carcinogenesis in hamsters. 2013 Apr 1
96 23220614 MAPK signaling pathways regulate mitochondrial-mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells. 2013 Mar 1
97 23353183 Crosstalk from survival to necrotic death coexists in DU-145 cells by curcumin treatment. 2013 May 2
98 23416140 JNK and p38 MAPK regulate oxidative stress and the inflammatory response in chlorpyrifos-induced apoptosis. 2013 Apr 26 1
99 23667638 Apoptosis of bone marrow mesenchymal stem cells caused by homocysteine via activating JNK signal. 2013 1
100 23696052 Biomarkers of sensitivity to potent and selective antitumor 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F203) in ovarian cancer. 2013 Oct 1