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mitogen-activated protein kinase 8 ; Homo sapiens







130 Article(s)
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1 34634178 Antitumour effect of odoroside A and its derivative on human leukaemia cells through the ROS/JNK pathway. 2022 Jan 1
2 34863979 Docetaxel-triggered SIDT2/NOX4/JNK/HuR signaling axis is associated with TNF-α-mediated apoptosis of cancer cells. 2022 Jan 1
3 34896468 Curcin C inhibit osteosarcoma cell line U2OS proliferation by ROS induced apoptosis, autophagy and cell cycle arrest through activating JNK signal pathway. 2022 Jan 15 1
4 34902437 Pancreastatin inhibitor PSTi8 prevents free fatty acid-induced oxidative stress and insulin resistance by modulating JNK pathway: In vitro and in vivo findings. 2022 Jan 15 2
5 35052632 Activity-Dependent Neuroprotective Protein (ADNP)-Derived Peptide (NAP) Counteracts UV-B Radiation-Induced ROS Formation in Corneal Epithelium. 2022 Jan 7 1
6 35100653 Antiproliferative and Microtubule-stabilizing Activities of Two Iboga-vobasine Bisindoles Alkaloids from Tabernaemontana corymbosa in Colorectal Adenocarcinoma HT-29 Cells. 2022 Jan 31 1
7 35198445 Indole Hydrazide Compound IHZ-1 Induces Apoptosis and Autophagy via Activation of ROS/JNK Pathway in Hepatocellular Carcinoma. 2022 2
8 35204104 Hyperoside and Quercitrin in Houttuynia cordata Extract Attenuate UVB-Induced Human Keratinocyte Cell Damage and Oxidative Stress via Modulation of MAPKs and Akt Signaling Pathway. 2022 Jan 24 1
9 35583119 Reverse anti-breast cancer drug resistance effects by a novel two-step assembled nano-celastrol medicine. 2022 Jun 1 1
10 35594653 Design, synthesis and antitumour activity of novel 5(6)-amino-benzimidazolequinones containing a fused morpholine. 2022 Aug 5 2
11 32640963 Periplogenin Activates ROS-ER Stress Pathway to Trigger Apoptosis via BIP-eIF2α- CHOP and IRE1α-ASK1-JNK Signaling Routes. 2021 1
12 33189448 Bisphenol AF induces apoptosis via estrogen receptor beta (ERβ) and ROS-ASK1-JNK MAPK pathway in human granulosa cell line KGN. 2021 Feb 1 1
13 33792698 The disulfiram/copper complex induces apoptosis and inhibits tumour growth in human osteosarcoma by activating the ROS/JNK signalling pathway. 2021 Oct 11 2
14 33932472 Intestinal guard: Human CXCL17 modulates protective response against mycotoxins and CXCL17-mimetic peptides development. 2021 Jun 1
15 33939975 A new synthetic antitumor naphthoquinone induces ROS-mediated apoptosis with activation of the JNK and p38 signaling pathways. 2021 Jul 1 1
16 34274415 Cisplatin induces autophagy-associated apoptosis in human oral squamous cell carcinoma (OSCC) mediated in part through reactive oxygen species. 2021 Sep 15 1
17 34332981 Dichloroacetate enhances the anti-tumor effect of sorafenib via modulating the ROS-JNK-Mcl-1 pathway in liver cancer cells. 2021 Sep 1 2
18 34369076 Caspase-3-mediated GSDME induced Pyroptosis in breast cancer cells through the ROS/JNK signalling pathway. 2021 Sep 1
19 34681736 OSMI-1 Enhances TRAIL-Induced Apoptosis through ER Stress and NF-κB Signaling in Colon Cancer Cells. 2021 Oct 14 2
20 34715512 Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade. 2021 Dec 1
21 34940569 AMPK-Mediated Metabolic Switching Is High Effective for Phytochemical Levo-Tetrahydropalmatine (l-THP) to Reduce Hepatocellular Carcinoma Tumor Growth. 2021 Nov 29 1
22 31629709 Schisantherin A induces cell apoptosis through ROS/JNK signaling pathway in human gastric cancer cells. 2020 Mar 1
23 32092796 Increased miR-34c mediates synaptic deficits by targeting synaptotagmin 1 through ROS-JNK-p53 pathway in Alzheimer's Disease. 2020 Mar 1
24 32121012 Activation of JNK and p38 in MCF-7 Cells and the In Vitro Anticancer Activity of Alnus hirsuta Extract. 2020 Feb 27 1
25 32157127 Downregulation of respiratory complex I mediates major signalling changes triggered by TOR activation. 2020 Mar 10 1
26 32370057 Curcumin Sensitizes Kidney Cancer Cells to TRAIL-Induced Apoptosis via ROS Mediated Activation of JNK-CHOP Pathway and Upregulation of DR4. 2020 May 1 1
27 32451640 Photobiomodulation with 808-nm diode laser enhances gingival wound healing by promoting migration of human gingival mesenchymal stem cells via ROS/JNK/NF-κB/MMP-1 pathway. 2020 Oct 1
28 32619557 Synergistic therapy with tangeretin and 5-fluorouracil accelerates the ROS/JNK mediated apoptotic pathway in human colorectal cancer cell. 2020 Sep 1
29 32708333 Compound Prunetin Induces Cell Death in Gastric Cancer Cell with Potent Anti-Proliferative Properties: In Vitro Assay, Molecular Docking, Dynamics, and ADMET Studies. 2020 Jul 21 1
30 32738660 Hierarchically constructed selenium-doped bone-mimetic nanoparticles promote ROS-mediated autophagy and apoptosis for bone tumor inhibition. 2020 Oct 1
31 32985606 Annurca apple polyphenol extract promotes mesenchymal-to-epithelial transition and inhibits migration in triple-negative breast cancer cells through ROS/JNK signaling. 2020 Sep 28 2
32 33013353 Inhibition of JNK-Mediated Autophagy Promotes Proscillaridin A- Induced Apoptosis via ROS Generation, Intracellular Ca+2 Oscillation and Inhibiting STAT3 Signaling in Breast Cancer Cells. 2020 1
33 33035517 Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells. 2020 Nov 1 1
34 33097606 Mitochondrial dysfunction triggers a catabolic response in chondrocytes via ROS-mediated activation of the JNK/AP1 pathway. 2020 Nov 30 1
35 33193889 Surfactin from Bacillus subtilis induces apoptosis in human oral squamous cell carcinoma through ROS-regulated mitochondrial pathway. 2020 2
36 33194716 Costunolide Induces Autophagy and Apoptosis by Activating ROS/MAPK Signaling Pathways in Renal Cell Carcinoma. 2020 1
37 33243299 Correction to: Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells. 2020 Nov 26 1
38 33364504 The efficacy of the anticancer 3-bromopyruvate is potentiated by antimycin and menadione by unbalancing mitochondrial ROS production and disposal in U118 glioblastoma cells. 2020 Dec 1
39 30447254 RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via JNK-dependent but p53-independent mechanism. 2019 Feb 1 1
40 31172987 A curcumin derivative, WZ35, suppresses hepatocellular cancer cell growth via downregulating YAP-mediated autophagy. 2019 Jun 19 1
41 31401057 ROS-mediated JNK pathway critically contributes to PFOS-triggered apoptosis in SH-SY5Y cells. 2019 Sep - Oct 8
42 31695327 Polyphyllin VI induces apoptosis and autophagy in human osteosarcoma cells by modulation of ROS/JNK activation. 2019 1
43 31776986 Oxidative Stress and Autophagy. 2019 1
44 29552311 MiR-29b reverses oxaliplatin-resistance in colorectal cancer by targeting SIRT1. 2018 Feb 23 1
45 29649125 Bavachinin Induces Oxidative Damage in HepaRG Cells through p38/JNK MAPK Pathways. 2018 Apr 12 1
46 29655083 Design, synthesis, anti-lung cancer activity, and chemosensitization of tumor-selective MCACs based on ROS-mediated JNK pathway activation and NF-κB pathway inhibition. 2018 May 10 2
47 29754474 Oxymatrine Causes Hepatotoxicity by Promoting the Phosphorylation of JNK and Induction of Endoplasmic Reticulum Stress Mediated by ROS in LO2 Cells. 2018 May 31 1
48 29766185 The curcumin derivative WZ35 activates ROS-dependent JNK to suppress hepatocellular carcinoma metastasis. 2018 May 23 2
49 30169763 Transcription Factor FOXO3a Is a Negative Regulator of Cytotoxicity of Fusarium mycotoxin in GES-1 Cells. 2018 Dec 1 2
50 30584464 High Glucose-Induced ROS Production Stimulates Proliferation of Pancreatic Cancer via Inactivating the JNK Pathway. 2018 2