Folic Acid

folate hydrolase 1 ; Homo sapiens







56 Article(s)
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Pub. Year
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1 34167925 Prostate-specific Membrane Antigen Biology in Lethal Prostate Cancer and its Therapeutic Implications. 2021 Jun 21 1
2 31492214 9,10-(Divinyl) Anthracene Based Bright Aggregation-Induced Emission Organic Dots for HeLa Cells Imaging. 2020 Apr 1 1
3 30844704 GCPII and its close homolog GCPIII: from a neuropeptidase to a cancer marker and beyond. 2019 Mar 1 1
4 31099011 Bioconjugated Gold Nanoparticles Enhance siRNA Delivery in Prostate Cancer Cells. 2019 2
5 29141866 Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors. 2018 Jan 2 2
6 29680672 Targeting of folate-conjugated liposomes with co-entrapped drugs to prostate cancer cells via prostate-specific membrane antigen (PSMA). 2018 Jun 2
7 30120883 Association of FOLH1, DHFR, and MTHFR gene polymorphisms with susceptibility of Neural Tube Defects: A case control study from Eastern India. 2018 Aug 15 2
8 28885600 A Cross-Sectional Study of Dietary and Genetic Predictors of Blood Folate Levels in Healthy Young Adults. 2017 Sep 8 3
9 27183249 Synthesis and characterization of a pH responsive folic acid functionalized polymeric drug delivery system. 2016 Jul-Aug 2
10 27188645 Bioconjugated gold nanoparticles enhance cellular uptake: A proof of concept study for siRNA delivery in prostate cancer cells. 2016 Jul 25 2
11 27378204 Ligand-targeted bacterial minicells: Futuristic nano-sized drug delivery system for the efficient and cost effective delivery of shRNA to cancer cells. 2016 Nov 1
12 27387982 Prostate-specific membrane antigen (PSMA)-mediated laminin proteolysis generates a pro-angiogenic peptide. 2016 Oct 3
13 27389146 Folate-targeted amphiphilic cyclodextrin.siRNA nanoparticles for prostate cancer therapy exhibit PSMA mediated uptake, therapeutic gene silencing in vitro and prolonged circulation in vivo. 2016 Nov 6
14 27917408 Prostate-Specific Membrane Antigen Targeted Polymersomes for Delivering Mocetinostat and Docetaxel to Prostate Cancer Cell Spheroids. 2016 Nov 30 1
15 26028103 Genetic Variation in Glutamate Carboxypeptidase II and Interaction with Dietary Natural Vitamin C May Predict Risk for Adenomatous Polyp Occurrence. 2015 3
16 26471812 Clinical utility of genetic variants of glutamate carboxypeptidase II in predicting breast cancer and prostate cancer risk. 2015 Nov 1
17 24863754 Structural and biochemical characterization of the folyl-poly-γ-l-glutamate hydrolyzing activity of human glutamate carboxypeptidase II. 2014 Jul 8
18 22918695 The maternal folate hydrolase gene polymorphism is associated with neural tube defects in a high-risk Chinese population. 2013 Mar 2
19 23266799 Association of glutamate carboxypeptidase II (GCPII) haplotypes with breast and prostate cancer risk. 2013 Mar 1 1
20 23777916 PSA-responsive and PSMA-mediated multifunctional liposomes for targeted therapy of prostate cancer. 2013 Sep 1
21 22310383 Paradoxical role of C1561T glutamate carboxypeptidase II (GCPII) genetic polymorphism in altering disease susceptibility. 2012 Apr 15 1
22 19830782 Expression of prostate-specific membrane antigen (PSMA), increases cell folate uptake and proliferation and suggests a novel role for PSMA in the uptake of the non-polyglutamated folate, folic acid. 2010 Feb 15 12
23 18234225 Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs. 2008 Mar 7 2
24 18842806 Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations. 2008 Oct 3
25 18974153 Moderate expression of prostate-specific membrane antigen, a tissue differentiation antigen and folate hydrolase, facilitates prostate carcinogenesis. 2008 Nov 1 3
26 19172696 The reduced folate carrier (RFC1) 80G > A and folate hydrolase 1 (FOLH1) 1561C > T polymorphisms and the risk of colorectal cancer: a nested case-referent study. 2008 3
27 17684227 Relations of glutamate carboxypeptidase II (GCPII) polymorphisms to folate and homocysteine concentrations and to scores of cognition, anxiety, and depression in a homogeneous Norwegian population: the Hordaland Homocysteine Study. 2007 Aug 4
28 16496414 Prostate specific membrane antigen (PSMA) expression gives prostate cancer cells a growth advantage in a physiologically relevant folate environment in vitro. 2006 Jun 1 3
29 15588157 Genetic determinants of folate status in Central Bohemia. 2005 2
30 15837926 Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase. 2005 Apr 26 2
31 15147814 Enhanced in vitro DNA transfection efficiency by novel folate-linked nanoparticles in human prostate cancer and oral cancer. 2004 May 31 2
32 15321811 Bioavailability of polyglutamyl folic acid relative to that of monoglutamyl folic acid in subjects with different genotypes of the glutamate carboxypeptidase II gene. 2004 Sep 2
33 15337665 Folate, homocysteine, and negative symptoms in schizophrenia. 2004 Sep 2
34 20641246 Quantum dot-prostate-specific membrane antigen antibody J591 2004 1
35 20641248 N-[N-[(S)-1,3-Dicarboxypropyl]carbamoyl]-S-[11C]methyl-L-cysteine 2004 1
36 20641404 64Cu-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-anti-prostate-specific membrane antigen 3/A12 monoclonal antibody 2004 1
37 20641595 N-[N-[(S)-1,3-Dicarboxypropyl]carbamoyl]-4-[18F]fluorobenzyl-L-cysteine 2004 1
38 20662139 IRDye800-2-(3-{5-[7-(5-amino-1-carboxy-pentylcarbamoyl)-heptanoylamino]-1-carboxy-pentyl}-ureido)-pentanedioic acid 2004 1
39 21634075 Quantum dot 800–prostate-specific membrane antigen antibody J591 2004 1
40 22379638 89Zr-Desferrioxamine B-7E11 anti-prostate-specific membrane antigen monoclonal antibody 2004 1
41 22400137 Quenched indocyanine green-anti-prostate-specific membrane antigen antibody J591 2004 1
42 23256224 2-(3-{1-Carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid 2004 1
43 23256225 111In-Labeled (7S)-26-(4-((1-((1-carboxy-5-(2-(4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetamido)pentyl)amino)-1-oxo-6-(1-((7S)-1,3,7,22-tetracarboxy-5,13,20-trioxo-4,6,12,21-tetraazahexacosan-26-yl)-1H-1,2,3-triazole-4-carboxamido)hexan-2-yl)carbamoyl)-1H-1,2,3-triazol-5-yl)-5,13,20-trioxo-4,6,12,21-tetraazahexacosane-1,3,7,22-tetracarboxylic acid 2004 1
44 23586109 Cy7-(3S,7S)-26-Amino-5,13,20-trioxo-4,6,12,21-tetraazahexacosane-1,3,7,22-tetracarboxylic acid 2004 1
45 12514270 The H475Y polymorphism in the glutamate carboxypeptidase II gene increases plasma folate without affecting the risk for neural tube defects in humans. 2003 Jan 8
46 12707400 Effect of glutamate carboxypeptidase II and reduced folate carrier polymorphisms on folate and total homocysteine concentrations in dialysis patients. 2003 May 6
47 12753319 Effects of the glutamate carboxypeptidase II (GCP2 1561C>T) and reduced folate carrier (RFC1 80G>A) allelic variants on folate and total homocysteine levels in kidney transplant patients. 2003 Jun 2
48 12855225 Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk. 2003 Jul 2
49 12949938 Effect of carbohydrate moieties on the folate hydrolysis activity of the prostate specific membrane antigen. 2003 Oct 1 1
50 12042430 The glutamate carboxypeptidase gene II (C>T) polymorphism does not affect folate status in the Framingham Offspring cohort. 2002 Jun 1